PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000219488

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

NAC

Protein Properties

Length: 199aa MW: 23276.7 Da PI: 6.5255

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000219488	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	132.9	2.2e-41	18	133	2	128
NAM 2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk 95 +pGfrFhPtdeelv +yLk+k+ +kkl++ +vi+e+d+yk++P++Lp+ +k+++++w+fFs+rd+ky+ g r++rat++g Wk tgkd++++ MDP0000219488 18 TPGFRFHPTDEELVLYYLKRKICKKKLKI-DVIAETDVYKWDPEELPElsPLKTGDRQWFFFSPRDRKYPXGXRSSRATRHGXWKXTGKDRTIT-- 110 69*************************.99**********9445778899*******************************995.. PP NAM 96 kgelvglkktLvfykgrapkgektdWvmheyrl 128 L +ykgrap+ge+tdWvmhey+l MDP0000219488 111 ----------LXYYKGRAPSGERTDWVMHEYTL 133 ..........69*****************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	3.01E-50	12	156	IPR003441	NAC domain
PROSITE profile	PS51005	33.424	17	156	IPR003441	NAC domain
Pfam	PF02365	3.7E-22	19	133	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 199 aa Download sequence Send to blast
MMTEDDSAAL FCDGHFATPG FRFHPTDEEL VLYYLKRKIC KKKLKIDVIA ETDVYKWDPE 60 ELPELSPLKT GDRQWFFFSP RDRKYPXGXR SSRATRHGXW KXTGKDRTIT LXYYKGRAPS 120 GERTDWVMHE YTLXEEELKR CENVQQYYAL YKVFQKSGPG PKNGEQYGAP FSEEDWVDDE 180 SPVIKTAADR QISVKQAVD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	3e-38	19	133	17	140	Stress-induced transcription factor NAC1
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.15056	3e-57	bud\| fruit\| leaf\| stem

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, rosette leaves, cauline leaves, shoot apex, stems and flowers. {ECO:0000269\|PubMed:17158162}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Transcriptional activator that acts as positive regulator of AOX1A during mitochondrial dysfunction. Binds directly to AOX1A promoter. Mediates mitochondrial retrograde signaling. {ECO:0000269\|PubMed:24045017}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold and drought stresses. {ECO:0000269\|PubMed:17158162}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028965254.1	1e-128	NAC domain-containing protein 17-like
Swissprot	Q9XIC5	3e-88	NAC17_ARATH; NAC domain-containing protein 17
TrEMBL	A0A498J057	1e-128	A0A498J057_MALDO; Uncharacterized protein
STRING	XP_009339761.1	1e-127	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF6131	34	51

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34190.1	8e-78	NAC domain containing protein 17

Link Out ? help Back to Top
Phytozome	MDP0000219488

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Van Aken O, et al. Mitochondrial and Chloroplast Stress Responses Are Modulated in Distinct Touch and Chemical Inhibition Phases. Plant Physiol., 2016. 171(3): p. 2150-65 [PMID:27208304] Van Aken O,Ford E,Lister R,Huang S,Millar AH Retrograde signalling caused by heritable mitochondrial dysfunction is partially mediated by ANAC017 and improves plant performance. Plant J., 2016. 88(4): p. 542-558 [PMID:27425258] Hu Z, et al. Mitochondrial Defects Confer Tolerance against Cellulose Deficiency. Plant Cell, 2016. 28(9): p. 2276-2290 [PMID:27543091] Chi YH, et al. The membrane-tethered NAC transcription factor, AtNTL7, contributes to ER-stress resistance in Arabidopsis. Biochem. Biophys. Res. Commun., 2017. 488(4): p. 641-647 [PMID:28088515] Van Aken O,Pogson BJ Convergence of mitochondrial and chloroplastic ANAC017/PAP-dependent retrograde signalling pathways and suppression of programmed cell death. Cell Death Differ., 2017. 24(6): p. 955-960 [PMID:28498364] Cheng P, et al. The ERA-Related GTPase AtERG2 Associated with Mitochondria 18S RNA Is Essential for Early Embryo Development in Arabidopsis. Front Plant Sci, 2018. 9: p. 182 [PMID:29497438]