PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000226701

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

NAC

Protein Properties

Length: 320aa MW: 36821.3 Da PI: 7.0281

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000226701	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	154.5	4.6e-48	7	125	1	118
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 +ppGfrFhPtdeelv++yL+kkv++++++l +vik+vd+yk+ePwdL++ ++ + e++ewyfFs++dkky+tg+r+nrat++g+Wkatg+dk+++ MDP0000226701 7 VPPGFRFHPTDEELVDYYLRKKVTSRRIDL-DVIKDVDLYKIEPWDLQElcRIGTeEQNEWYFFSHKDKKYPTGTRTNRATAAGFWKATGRDKAIY 101 69**************************.9***********954555442556*********************************** PP NAM 94 skkgelvglkktLvfykgrapkgek 118 s k+ l+g++ktLvfykgrap+g+k MDP0000226701 102 S-KHDLIGMRKTLVFYKGRAPNGQK 125 .8899****************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	7.19E-51	5	155	IPR003441	NAC domain
PROSITE profile	PS51005	49.16	7	155	IPR003441	NAC domain
Pfam	PF02365	7.6E-23	8	127	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 320 aa Download sequence Send to blast
METFSHVPPG FRFHPTDEEL VDYYLRKKVT SRRIDLDVIK DVDLYKIEPW DLQELCRIGT 60 EEQNEWYFFS HKDKKYPTGT RTNRATAAGF WKATGRDKAI YSKHDLIGMR KTLVFYKGRA 120 PNGQKEHTLN GQCSYSILVQ LKQEEGWVVC RVFKKKIASM RIKMSENESP CWYDDQVSFM 180 PELDSPGHNS SSMNMNMVPY HHLPNYPCKK ELDHLPFQVP QEHFFQLPLL GSPKLVQSSS 240 ATAVSSSNSM APHAYSIDIN HTCTFQSSDQ DQNFHGVVYG NSSNDDHQRA VDQLTDWRAL 300 DKFVASQLSQ DDASKGNSYS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	1e-41	2	156	10	169	Stress-induced transcription factor NAC1
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Up-regulated during xylem vessel element formation. Expressed preferentially in procambial cells adjacent to root meristem. {ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:25148240}.
Uniprot	TISSUE SPECIFICITY: Expressed in root, shoot and hypocotyl vascular elements, columella root caps, epidermal and cortex root cells and root-hypocotyl junctions. Observed predominantly in root imature xylem vessels (PubMed:18445131). Present in root developing xylems (PubMed:16103214, PubMed:17565617). Specifically expressed in vessels in the secondary xylem of the root-hypocotyl region, and in vessels but not in interfascicular fibers in stems (PubMed:25148240). {ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:17565617, ECO:0000269\|PubMed:18445131, ECO:0000269\|PubMed:25148240}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:16103214, PubMed:25148240). {ECO:0000250\|UniProtKB:Q9LVA1, ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:25148240}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008376439.1	0.0	NAC domain-containing protein 7-like
Swissprot	Q9FWX2	1e-113	NAC7_ARATH; NAC domain-containing protein 7
TrEMBL	M5X778	0.0	M5X778_PRUPE; Uncharacterized protein
STRING	XP_008376439.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1269	33	106

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12260.1	1e-102	NAC 007

Link Out ? help Back to Top
Phytozome	MDP0000226701

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469]