PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000232116
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ARF
Protein Properties Length: 587aa    MW: 64643.8 Da    PI: 6.004
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000232116genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B376.82.4e-24122223199
                    EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE CS
             B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsef 90 
                    f k+ltpsd+++ g +++pk +a+++      + +++ +  l l+d++g +We+++iyr++++r++lt+GW++Fv+ + L +gD+vvF+  ++ ++
  MDP0000232116 122 FAKILTPSDAHNGGGFSVPKFCADTIfpplnfQADPPIQ-ALFLTDLHGVVWEFRHIYRGTPRRHLLTTGWSKFVNHKMLVAGDSVVFM--RNGRG 214
                    89******************999999*****96666775.8************************************************..45789 PP

                    ..EEEEE-S CS
             B3  91 elvvkvfrk 99 
                    e++++v+r+
  MDP0000232116 215 EMFIGVRRA 223
                    999***996 PP
2Auxin_resp83.93.4e-28270353183
     Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrl.sGtvvgvsdldpvrWpnSkWrsLk 83 
                    +a+ a+++++FevvY+P+a++ +Fvvk e vekalkv +++GmR+k+a+etedss+ ++ +Gt +  s  d+  W++S+Wr+L+
  MDP0000232116 270 VAEMAAEGKPFEVVYYPKAGWWDFVVKSEVVEKALKVFWTAGMRVKLAMETEDSSRMTWfQGTLSMASVPDNGPWQGSPWRMLQ 353
                    578899****************************************************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019366.28E-29112242IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.107.5E-35116232IPR015300DNA-binding pseudobarrel domain
CDDcd100171.41E-20120218No hitNo description
PfamPF023622.3E-22122223IPR003340B3 DNA binding domain
SMARTSM010193.8E-20122224IPR003340B3 DNA binding domain
PROSITE profilePS5086312.605122224IPR003340B3 DNA binding domain
PfamPF065071.4E-25271353IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 587 aa     Download sequence    Send to blast
MPPPHGRSID PKVWRACAGN SVQIPTLNSR VYYFPQGHLE QSSPSSAAPV LLSPLLLSKP  60
LILCRISDLR FLADPTTDEV FAKLLLVPIP NEFPSIEPPN GDKLDADGNG DLERQDDRVF  120
SFAKILTPSD AHNGGGFSVP KFCADTIFPP LNFQADPPIQ ALFLTDLHGV VWEFRHIYRG  180
TPRRHLLTTG WSKFVNHKML VAGDSVVFMR NGRGEMFIGV RRAVRASASS DCARWSYHIG  240
GGATNSMRLK TEDQDCSGRK VXSAEAVAEV AEMAAEGKPF EVVYYPKAGW WDFVVKSEVV  300
EKALKVFWTA GMRVKLAMET EDSSRMTWFQ GTLSMASVPD NGPWQGSPWR MLQVTWDEPE  360
ALHNAKRVSP WQVEFVGSTP SIHTTFCPTK RFRAPLSHGL LINAEEEFFF PMTGAANLAM  420
GPFSASLLNY NFPAGMQGAR QDTFSVSNLS HLLSENSPQA CTYNSFGNNE VPKLKRVCTE  480
LNIGSSQSDE LSPDSQSSVA SFGMELDGNR LQTKVGTSSF QLFGKIIHTN QSVEGGSDDV  540
GCTEDSGNKE YNVAEGGHNH LDLNFTELLD RIDIKCQKTS AVDSCTL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldx_A1e-661237822357Auxin response factor 1
4ldx_B1e-661237822357Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008338805.20.0auxin response factor 17
SwissprotQ84WU61e-176ARFQ_ARATH; Auxin response factor 17
TrEMBLA0A498HYG70.0A0A498HYG7_MALDO; Multifunctional fusion protein
STRINGXP_008338805.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40303056
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G77850.11e-169auxin response factor 17
Publications ? help Back to Top
  1. Shi ZH, et al.
    Overexpression of AtTTP affects ARF17 expression and leads to male sterility in Arabidopsis.
    PLoS ONE, 2015. 10(3): p. e0117317
    [PMID:25822980]
  2. de Lucas M, et al.
    Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.
    Plant Cell, 2016. 28(10): p. 2616-2631
    [PMID:27650334]
  3. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  4. Wang B, et al.
    Fine regulation of ARF17 for anther development and pollen formation.
    BMC Plant Biol., 2017. 17(1): p. 243
    [PMID:29258431]
  5. Wójcik AM,Nodine MD,Gaj MD
    miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 2024
    [PMID:29321785]
  6. Lin JS, et al.
    MicroRNA160 Modulates Plant Development and Heat Shock Protein Gene Expression to Mediate Heat Tolerance in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 68
    [PMID:29449855]