PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000239523
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family NF-X1
Protein Properties Length: 821aa    MW: 92163.9 Da    PI: 8.4848
Description NF-X1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000239523genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-NF-X122.72.1e-07231249119
       zf-NF-X1   1 CGkHkCqklCHeGpCppCp 19 
                    CG+H+C+++CH GpC pC+
  MDP0000239523 231 CGIHRCSEICHQGPCLPCR 249
                    ******************6 PP
2zf-NF-X118.44.6e-06285303119
       zf-NF-X1   1 CGkHkCqklCHeGpCppCp 19 
                    CG+HkC k CH+G+C+pCp
  MDP0000239523 285 CGQHKCTKGCHLGECGPCP 303
                    ******************9 PP
3zf-NF-X118.15.7e-06392411120
       zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                    CG+H C++ C+ G+CppC++
  MDP0000239523 392 CGRHACKRRCCDGDCPPCSE 411
                    ******************85 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF578505.42E-661138No hitNo description
PROSITE patternPS01359066132IPR019786Zinc finger, PHD-type, conserved site
CDDcd060087.14E-7167215No hitNo description
PfamPF014220.066179196IPR000967Zinc finger, NF-X1-type
SMARTSM004380.072179197IPR000967Zinc finger, NF-X1-type
CDDcd060081.22E-5221256No hitNo description
PfamPF014222.3E-5231249IPR000967Zinc finger, NF-X1-type
SMARTSM004382.9E-4231250IPR000967Zinc finger, NF-X1-type
CDDcd060087.29E-10275315No hitNo description
PfamPF014220.0057285303IPR000967Zinc finger, NF-X1-type
SMARTSM004380.0059285304IPR000967Zinc finger, NF-X1-type
CDDcd060081.35E-9329378No hitNo description
PfamPF014220.0024339358IPR000967Zinc finger, NF-X1-type
SMARTSM004380.042339359IPR000967Zinc finger, NF-X1-type
CDDcd060085.58E-5382430No hitNo description
PfamPF014227.9E-4392410IPR000967Zinc finger, NF-X1-type
SMARTSM004380.0092392411IPR000967Zinc finger, NF-X1-type
SMARTSM00438100449470IPR000967Zinc finger, NF-X1-type
PfamPF01422100459469IPR000967Zinc finger, NF-X1-type
PfamPF01422110478487IPR000967Zinc finger, NF-X1-type
SMARTSM00438140478523IPR000967Zinc finger, NF-X1-type
SMARTSM004380.027586604IPR000967Zinc finger, NF-X1-type
PfamPF014220.55588603IPR000967Zinc finger, NF-X1-type
SMARTSM0043814649670IPR000967Zinc finger, NF-X1-type
PfamPF014225.7651668IPR000967Zinc finger, NF-X1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007623Biological Processcircadian rhythm
GO:0009651Biological Processresponse to salt stress
GO:0009908Biological Processflower development
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0042335Biological Processcuticle development
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000037Biological Processregulation of stomatal complex patterning
GO:0005634Cellular Componentnucleus
GO:0000987Molecular Functioncore promoter proximal region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 821 aa     Download sequence    Send to blast
MPSNHSDSDT DSDQSQSGSG PVRHSDLSDS IFRTYLEFTG KSTATTADLS KIQSFLTSSS  60
SGALSCLICL ERIRPADPTW SCTSVCFSVF HLICIQSWAR QASDLSALRA STRLPISAQK  120
AAEVSVWNCP KCRIEYPHSQ IPKNYYCFCG KLENPPSDDP WVLPHSCGEV CNRPLKHGCG  180
HHCLLLCHPG PCPSCPKLVE SRCFCGSVKD VRRCGFKYFS CNNACKKVLA CGIHRCSEIC  240
HQGPCLPCRV RGVYRCQCGK KEEEKECCER LDFRCEEPCE KVLGCGQHKC TKGCHLGECG  300
PCPSQGKRTC PCGKRMHEGL SCKASVPLCG STCDKMLSCG YHRCPERCHR GECIETCRTV  360
VIKYCRCGSL KKEVPCHQDL ACERKCQRLR DCGRHACKRR CCDGDCPPCS EVCVPRSASD  420
FRSILVPCGT EMDQKPPRCR KPCPITPLCR HGPNSKPHKC HYGACHPCRL LCEEEYPCGH  480
NCKLRCHGPK PPPNPEFTLK PKKKKSFHQS ESTPGSPCPP CPELVWRSCV GQHIGADKMI  540
KHYFPAKTCA EILYLVVITF AQKLVTPSRI KRCHQSDKQE EREPACPHPC PLPCHPGDCP  600
PCKVLVKRSC HCGSMVHVFE CIYFNSLSEK EQMAARSCKG PCHRKLPYCT HLCPEICHPG  660
QCSSPEKCSK KVTVRCGCQS LKKEWLCHNV QAAYRDAGSD PKDVFKNQFG LGLIPCNSDC  720
KSKQKVNDSE LQLRRPKSVE VKESDNDRQG PKRKKRRERL QQVTQTSTLQ KIISNVKRCL  780
LVFTLLVVLV AVSYYGYKGL LRLNDWMNEV EENRQRRYPR I
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1750756PKRKKRR
2752758RKKRRER
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.158611e-151fruit| leaf
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Constitutively expressed in mesophyll and guard cells. {ECO:0000269|PubMed:22073231}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcriptional regulator. May mediate E2- or E3-dependent ubiquitination. Required to gate light sensitivity during the night. Regulates the speed of the clock by acting in the feedback loop between CCA1, LHY and APRR1/TOC1. Promotes the expression of CCA1 at night but not by days. This activational effect is enhanced by interaction with ADO1/ZTL. Association with ADO1/ZTL is not leading to the degradation of NFXL2. Confers sensitivity to osmotic stress such as high salinity. Prevents H(2)O(2) production and abscisic acid accumulation. Part of a regulatory network that integrates the biosynthesis and action of abscisic acid, reactive oxygen species and cuticle components. {ECO:0000269|PubMed:16905136, ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:21429190, ECO:0000269|PubMed:22073231, ECO:0000269|PubMed:22516817}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with a peak of expression at or before dawn. Not regulated by biotic and abiotic stresses, by light and nutrient conditions or upon treatment with elicitors, chemicals, abscisic acid or phytohormones. {ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:22073231}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028954530.10.0LOW QUALITY PROTEIN: NF-X1-type zinc finger protein NFXL2-like
SwissprotQ9FFK80.0NFXL2_ARATH; NF-X1-type zinc finger protein NFXL2
TrEMBLA0A498JHU00.0A0A498JHU0_MALDO; Uncharacterized protein
STRINGXP_008369256.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF102253237
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G05660.10.0sequence-specific DNA binding transcription factors;zinc ion binding;sequence-specific DNA binding transcription factors