PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000242612
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MYB_related
Protein Properties Length: 193aa    MW: 22380.9 Da    PI: 6.3931
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000242612genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding39.81e-123388145
                     TSSS-HHHHHHHHHHHHHTTTT............-HHHHHHHHTTTS-HHHHHHHHH CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGgg............tWktIartmgkgRtlkqcksrwq 45
                     rg+ ++eE++l++++ k+lG++            +W++Ia +++ g t++++k++w+
    MDP0000242612 33 RGNISPEEEDLIIRLQKLLGNRydiflhinsvnpRWSLIAGRLP-GQTDNEIKNFWN 88
                     7999****************************************.***********7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.2E-111339IPR009057Homeodomain-like
PROSITE profilePS500904.3791327IPR017877Myb-like domain
SuperFamilySSF466892.79E-161396IPR009057Homeodomain-like
PROSITE profilePS5129415.6132895IPR017930Myb domain
SMARTSM007172.3E-93293IPR001005SANT/Myb domain
PfamPF002491.3E-103388IPR001005SANT/Myb domain
CDDcd001673.05E-73788No hitNo description
Gene3DG3DSA:1.10.10.601.7E-154090IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 193 aa     Download sequence    Send to blast
MTEVQQGCVV GLNRSGKSCR LRWLNYLKPD IKRGNISPEE EDLIIRLQKL LGNRYDIFLH  60
INSVNPRWSL IAGRLPGQTD NEIKNFWNIS LSKRIQEERP RRGTNSSQAP NDGDNRHQLS  120
NYCSNPSKDD DDQSNPVFED LVLREESHIE AAKWKYWCAT SDHLLFQPNH EDVDLHAISA  180
FLNSQDGYHP WIN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3zqc_A1e-13139534103MYB3
3zqc_D1e-13139534103MYB3
3zqc_G1e-13139534103MYB3
3zqc_J1e-13139534103MYB3
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Highly expressed from the very early stages of embryogenesis to the globular stage, decreases rapidly from the late heart-torpedo stage and did not persist after the completion of embryogenesis.
UniprotTISSUE SPECIFICITY: Expressed at a high level in immature siliques and at a lower level in flowers. Undetected in young seedlings, roots, leaves and inflorescence stems.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator, when associated with BHLH2/EGL3/MYC146, BHLH12/MYC1, or BHLH42/TT8. Involved in the control of flavonoid late metabolism in developing siliques. Plays a key role in determining the tissue-specific activation of leucoanthocyanidin reductase (BANYULS). {ECO:0000269|PubMed:15361138}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028944735.14e-79transcription factor WER-like
SwissprotQ9FJA23e-30TT2_ARATH; Transcription factor TT2
TrEMBLA0A498HVH41e-122A0A498HVH4_MALDO; Uncharacterized protein
STRINGXP_009361730.18e-78(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF1785547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G35550.11e-32MYB family protein
Publications ? help Back to Top
  1. Coego A, et al.
    The TRANSPLANTA collection of Arabidopsis lines: a resource for functional analysis of transcription factors based on their conditional overexpression.
    Plant J., 2014. 77(6): p. 944-53
    [PMID:24456507]
  2. Liu C,Jun JH,Dixon RA
    MYB5 and MYB14 Play Pivotal Roles in Seed Coat Polymer Biosynthesis in Medicago truncatula.
    Plant Physiol., 2014. 165(4): p. 1424-1439
    [PMID:24948832]
  3. Zhu Z, et al.
    Characterization of the cis elements in the proximal promoter regions of the anthocyanin pathway genes reveals a common regulatory logic that governs pathway regulation.
    J. Exp. Bot., 2015. 66(13): p. 3775-89
    [PMID:25911741]
  4. Liu Y,Shi Z,Maximova SN,Payne MJ,Guiltinan MJ
    Tc-MYBPA an Arabidopsis TT2-like transcription factor and functions in the regulation of proanthocyanidin synthesis in Theobroma cacao.
    BMC Plant Biol., 2015. 15: p. 160
    [PMID:26109181]
  5. Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN
    The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors.
    Plant Physiol. Biochem., 2016. 102: p. 70-9
    [PMID:26913794]
  6. Li Y, et al.
    Two IIIf Clade-bHLHs from Freesia hybrida Play Divergent Roles in Flavonoid Biosynthesis and Trichome Formation when Ectopically Expressed in Arabidopsis.
    Sci Rep, 2016. 6: p. 30514
    [PMID:27465838]
  7. Li C,Zhang B,Chen B,Ji L,Yu H
    Site-specific phosphorylation of TRANSPARENT TESTA GLABRA1 mediates carbon partitioning in Arabidopsis seeds.
    Nat Commun, 2018. 9(1): p. 571
    [PMID:29422671]