PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000254112
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family NAC
Protein Properties Length: 356aa    MW: 41421.9 Da    PI: 6.5071
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000254112genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM175.81.2e-5471361129
            NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 
                    +ppGfrFhPtdeelv++yL+kk+++k++++ +v+++vd+yk+ePwdL+   k+ + +++ewyfFs++dkky+tg+r+nratk+g+Wkatg+dk+++
  MDP0000254112   7 VPPGFRFHPTDEELVDYYLRKKTASKPIDF-DVVRDVDLYKIEPWDLEDlcKIGSgDQNEWYFFSHKDKKYPTGHRSNRATKAGFWKATGRDKAIY 101
                    69****************************.99**************943466553556************************************* PP

            NAM  94 skkgelvglkktLvfykgrapkgektdWvmheyrle 129
                    + ++ lvg++ktLvfykgrap+g+k+dW+mheyrle
  MDP0000254112 102 R-GKFLVGMRKTLVFYKGRAPNGQKSDWIMHEYRLE 136
                    *.999*****************************85 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.19E-565140IPR003441NAC domain
PROSITE profilePS5100554.2197152IPR003441NAC domain
PfamPF023653.4E-288135IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 356 aa     Download sequence    Send to blast
MDTLSHVPPG FRFHPTDEEL VDYYLRKKTA SKPIDFDVVR DVDLYKIEPW DLEDLCKIGS  60
GDQNEWYFFS HKDKKYPTGH RSNRATKAGF WKATGRDKAI YRGKFLVGMR KTLVFYKGRA  120
PNGQKSDWIM HEYRLETSEN GTPQAMKRMG DYESPNCYDQ VPFXQQLDNS PRTSISHTYV  180
SSQYQQQLHY SQCKPELDLQ YNMPHHHHDS FLQLPQLESP KVPHQPAXPY GNYVIQSSTV  240
LTQEEQLHYF CQQNPFNSSA SSSGHXHYNN TDYLQAVDQV KDWQALDKYV ASQLSHDQQD  300
ASKEVTNYSN AEETFHVAEH INMLANEASR RPDYNNNGQE YYASTSTSSC QIDLWK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ulx_A1e-44613514140Stress-induced transcription factor NAC1
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Up-regulated during xylem vessel element formation. Expressed preferentially in procambial cells adjacent to root meristem. {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:25148240}.
UniprotTISSUE SPECIFICITY: Expressed in root, shoot and hypocotyl vascular elements, columella root caps, epidermal and cortex root cells and root-hypocotyl junctions. Observed predominantly in root imature xylem vessels (PubMed:18445131). Present in root developing xylems (PubMed:16103214, PubMed:17565617). Specifically expressed in vessels in the secondary xylem of the root-hypocotyl region, and in vessels but not in interfascicular fibers in stems (PubMed:25148240). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17565617, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:25148240}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:16103214, PubMed:25148240). {ECO:0000250|UniProtKB:Q9LVA1, ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:25148240}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008385273.20.0NAC domain-containing protein 7-like
SwissprotQ9FWX21e-115NAC7_ARATH; NAC domain-containing protein 7
TrEMBLA0A498JU370.0A0A498JU37_MALDO; Uncharacterized protein
STRINGXP_008385273.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF126933106
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12260.11e-116NAC 007
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]