PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000256621
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ARF
Protein Properties Length: 957aa    MW: 106507 Da    PI: 8.6839
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000256621genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B376.23.7e-24224325199
                    EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSE CS
             B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrse 89 
                    f k+ltpsd+++ g +++p+ +a+++         ++ +  +l+++d++g +We+++iyr++++r++lt+GW++Fv+ + L +gD+vvF+  ++ +
  MDP0000256621 224 FAKILTPSDANNGGGFSVPRFCADSIfpplnyqADPPVQ--MLSVTDLHGVVWEFRHIYRGTPRRHLLTTGWSKFVNHKMLVAGDSVVFM--RNGR 315
                    89*********************999****995444444..8************************************************..4578 PP

                    E..EEEEE-S CS
             B3  90 felvvkvfrk 99 
                    +e++++v+r+
  MDP0000256621 316 GEMFIGVRRA 325
                    9999***996 PP
2Auxin_resp873.6e-29372455183
     Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrl.sGtvvgvsdldpvrWpnSkWrsLk 83 
                    +a+ a+++ +FevvY+P+a++s+Fvvk+e vekalkv +++GmR+k+a+etedss+ ++ +Gt +  s  ++  W+ S+Wr+Lk
  MDP0000256621 372 VAEMAAEGRPFEVVYYPKAGWSDFVVKAEVVEKALKVFWTAGMRVKLAMETEDSSRMTWfQGTLSTASVPENGPWQSSPWRMLK 455
                    578899****************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.96E-30215353IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.109.6E-36218335IPR015300DNA-binding pseudobarrel domain
CDDcd100175.72E-20223320No hitNo description
SMARTSM010197.1E-21224326IPR003340B3 DNA binding domain
PROSITE profilePS5086312.605224326IPR003340B3 DNA binding domain
PfamPF023629.3E-22224325IPR003340B3 DNA binding domain
PfamPF065075.2E-26373455IPR010525Auxin response factor
HamapMF_0115116.831719937IPR000740GrpE nucleotide exchange factor
Gene3DG3DSA:3.90.20.202.6E-22780878IPR013805GrpE nucleotide exchange factor, coiled-coil
PfamPF010251.2E-40781936IPR000740GrpE nucleotide exchange factor
SuperFamilySSF580146.41E-20785878No hitNo description
CDDcd004461.63E-41802935IPR000740GrpE nucleotide exchange factor
PRINTSPR007731.9E-21806822IPR000740GrpE nucleotide exchange factor
PRINTSPR007731.9E-21834849IPR000740GrpE nucleotide exchange factor
Gene3DG3DSA:2.30.22.101.5E-19882939IPR009012GrpE nucleotide exchange factor, head
SuperFamilySSF510641.02E-14883938IPR009012GrpE nucleotide exchange factor, head
PRINTSPR007731.9E-21889904IPR000740GrpE nucleotide exchange factor
PROSITE patternPS010710892935IPR000740GrpE nucleotide exchange factor
PRINTSPR007731.9E-21916935IPR000740GrpE nucleotide exchange factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0006457Biological Processprotein folding
GO:0009725Biological Processresponse to hormone
GO:0010208Biological Processpollen wall assembly
GO:0048830Biological Processadventitious root development
GO:0052543Biological Processcallose deposition in cell wall
GO:0005634Cellular Componentnucleus
GO:0000774Molecular Functionadenyl-nucleotide exchange factor activity
GO:0000987Molecular Functioncore promoter proximal region sequence-specific DNA binding
GO:0042803Molecular Functionprotein homodimerization activity
GO:0051087Molecular Functionchaperone binding
Sequence ? help Back to Top
Protein Sequence    Length: 957 aa     Download sequence    Send to blast
MEVVDGFRRN RVNHNVILVD RLGRWRATDQ KWXEEVVGRP RVMGHGGERL IVRWHRRDVR  60
RQVADRWEGR RRRKKTTGXX SPGRRDRSQL KISNMPPPRQ PHSHSHRRSI DPKIWRACAG  120
NSVQIPSLHS RVYYFPQGHL EQSSTSSSSS AALLSPLLLS KPLILCRISA LHFLAVPTTD  180
EVFAKXLLVP IPQEFPNREQ PNGEEFDADD GGDSERQDDK VVSFAKILTP SDANNGGGFS  240
VPRFCADSIF PPLNYQADPP VQMLSVTDLH GVVWEFRHIY RGTPRRHLLT TGWSKFVNHK  300
MLVAGDSVVF MRNGRGEMFI GVRRAVRSTA SSDCARLSSQ IGGGVTYSTR LNTEDQDCSG  360
GKVMSAEAVT EVAEMAAEGR PFEVVYYPKA GWSDFVVKAE VVEKALKVFW TAGMRVKLAM  420
ETEDSSRMTW FQGTLSTASV PENGPWQSSP WRMLKVTWDE PEVLQNAKRV SPWEVEFVGP  480
TPSIHTTFSP TKRFRAPLSH GLLTNAEGEF FFPMMGAANS AMVPFSASLL NYNNFPAGMQ  540
GARQDTFCVS NLSHLLSENT PQMCTFNSIG KNEGQKLKRV CTELNIGSSQ SDELSPDSQS  600
SVQSFGMELD GNRLQTKVGR SSFQLFGKII YMNQPVEGGF DDVGCTEDSG NKGYNETEEG  660
HSQLDLSFTK LIDVQCQKSS AVEAWFINFS LTSNSSSSII NPSSRRRAAS SFKSRLAPQD  720
SVPPTNSRKE SSKSNAGPSG SGGDEEQLPS LKTLLKVYKE AIFNGDGKTV SEVEAIIQVI  780
ENEKKELVEK VSSASAEITS GKEKLIRLQA DFDNCRKRFD KERLTVRTDA QGEVIESLLP  840
MVDNFERARQ YLKPETEQEK KIDASYQGIY KQFVEIMRSL DVAVVPTVGK PFDPSLHEAI  900
AREESQELKE GIIIQEIRRG FLLGGRLLRP ATVKVSSGPG SXKSPVATEK TTAGVEK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A4e-6511347622353Auxin response factor 1
4ldw_A4e-6511347622353Auxin response factor 1
4ldw_B4e-6511347622353Auxin response factor 1
4ldx_A5e-6511347622353Auxin response factor 1
4ldx_B5e-6511347622353Auxin response factor 1
4ldy_A5e-6511347622353Auxin response factor 1
4ldy_B5e-6511347622353Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008347772.20.0auxin response factor 17-like
SwissprotQ84WU61e-178ARFQ_ARATH; Auxin response factor 17
TrEMBLA0A498HYG70.0A0A498HYG7_MALDO; Multifunctional fusion protein
STRINGXP_008347772.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40303056
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G77850.11e-162auxin response factor 17
Publications ? help Back to Top
  1. Shi ZH, et al.
    Overexpression of AtTTP affects ARF17 expression and leads to male sterility in Arabidopsis.
    PLoS ONE, 2015. 10(3): p. e0117317
    [PMID:25822980]
  2. de Lucas M, et al.
    Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.
    Plant Cell, 2016. 28(10): p. 2616-2631
    [PMID:27650334]
  3. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  4. Wang B, et al.
    Fine regulation of ARF17 for anther development and pollen formation.
    BMC Plant Biol., 2017. 17(1): p. 243
    [PMID:29258431]
  5. Wójcik AM,Nodine MD,Gaj MD
    miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 2024
    [PMID:29321785]
  6. Lin JS, et al.
    MicroRNA160 Modulates Plant Development and Heat Shock Protein Gene Expression to Mediate Heat Tolerance in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 68
    [PMID:29449855]