PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000264803

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

bHLH

Protein Properties

Length: 249aa MW: 27570.2 Da PI: 8.7176

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000264803	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	35	2.6e-11	92	139	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE+ RRdr+N++f eL ++l + + +K +Ka+iL Av+ +++L MDP0000264803 92 SKACREKLRRDRLNDKFVELGSILEPG---RPPKTDKAAILVDAVRMVNQL 139 5678********************8...89*************9999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	13.3	88	139	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.70E-8	91	144	No hit	No description
Gene3D	G3DSA:4.10.280.10	7.8E-13	92	162	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.7E-9	92	139	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.66E-13	93	163	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.8E-9	94	145	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 249 aa Download sequence Send to blast
MASPENTNWL FDYGLIDDTP VLDGNFAWPV QPIAGSSSAR LGCVYGCSFI ILWRLYLFCS 60 VELDGSLGDA EGLKESGSKK RVRTESCSGT SSKACREKLR RDRLNDKFVE LGSILEPGRP 120 PKTDKAAILV DAVRMVNQLR GEAQKLKDTN SGLQEKIKEL KAEKNELRDE KQRLKSEKEK 180 LEQQLKSMNX QPGFLPPPPA IPAAFAAQXQ ARGNKMVPFI GYPGVAMWQF MPPAAVDTSQ 240 DHVLRPPVA

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.13146	0.0	bud\| cell culture\| fruit\| leaf\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269\|PubMed:17028341}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP689422	0.0	KP689422.1 Prunus pseudocerasus isolate Unigene14053 bHLH transcription factor mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008365724.1	1e-155	transcription factor ILR3
Swissprot	Q9FH37	1e-109	ILR3_ARATH; Transcription factor ILR3
TrEMBL	D9ZIP0	1e-148	D9ZIP0_MALDO; BHLH domain class transcription factor
STRING	XP_008365724.1	1e-154	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1602	34	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	3e-85	bHLH family protein

Link Out ? help Back to Top
Phytozome	MDP0000264803

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]