PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000269641

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 253aa MW: 28566.9 Da PI: 10.0402

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000269641	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14	0.00015	43	65	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+ F r nL+ H r H MDP0000269641 43 FVCEICNNGFQRDQNLQLHRRGH 65 89*******************88 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.62E-6	42	65	No hit	No description
Gene3D	G3DSA:3.30.160.60	7.6E-4	43	65	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.18	43	65	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	45	65	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.62E-6	114	139	No hit	No description
SuperFamily	SSF53474	5.91E-6	167	235	IPR029058	Alpha/Beta hydrolase fold
Gene3D	G3DSA:3.40.50.1820	8.9E-7	196	235	IPR029058	Alpha/Beta hydrolase fold

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 253 aa Download sequence Send to blast
MPRLTLKFGV VEMQTMVKKY QQRFSKADVI ALSLTTLLAT NHFVCEICNN GFQRDQNLQL 60 HRRGHNLPWK LQQRSGKEVK KRVYVCPETS CVHHDPSRAL SDLTGIKKCF CKKHGEKKWK 120 CDKCSKKYAV QSDWNAHPKI CGTREYKCDC GTLSSRRDSF ITHRVFFSHL LSSLIRFTSD 180 GEQKINPKIN GVDGSEANPL NPTSYSILHL VGDLVGLLDH FGGQQAFVVG HGHGALGKEK 240 GDNQKKAKAN LCR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	6e-28	115	179	3	67	Zinc finger protein JACKDAW
5b3h_F	6e-28	115	179	3	67	Zinc finger protein JACKDAW
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Observed in vegetative tissues. Mainly expressed in hypocotyls, petioles, shoot apices, root tips, and trichomes, and, at low levels, in leaves, stems and flowers. {ECO:0000269\|PubMed:25035403}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017622160.1	2e-90	PREDICTED: protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	8e-89	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A498I9V5	1e-136	A0A498I9V5_MALDO; Uncharacterized protein
STRING	Gorai.003G016200.1	5e-89	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	9e-72	indeterminate(ID)-domain 2

Link Out ? help Back to Top
Phytozome	MDP0000269641

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]