PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000277643
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family AP2
Protein Properties Length: 543aa    MW: 60585.4 Da    PI: 6.5494
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000277643genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP233.51e-10243299155
            AP2   1 sgykGVrwdkkrgrWvAeIrd.pseng...krkrfslgkfgtaeeAakaaiaarkkleg 55 
                    s y+GV++++++gr++A+++d  +       rk  + g ++ +++Aa+a++ a++k++g
  MDP0000277643 243 SIYRGVTRHRWTGRYEAHLWDnSCR-RegqARKGRQ-GGYDKEDKAARAYDLAALKYWG 299
                    57*******************4444.2344336655.7799999*************98 PP
2AP249.88.8e-16360411155
            AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    s y+GV++++++grW A+I  +     +k  +lg+f t+eeAa+a++ a+ k++g
  MDP0000277643 360 SIYRGVTRHHQQGRWQARIGRVAG---NKDLYLGTFATEEEAAEAYDIAAIKFRG 411
                    57****************988532...5************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000185.52E-19243308No hitNo description
PfamPF008471.9E-8243299IPR001471AP2/ERF domain
SuperFamilySSF541712.42E-14243308IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.105.4E-12244308IPR001471AP2/ERF domain
PROSITE profilePS5103217.346244307IPR001471AP2/ERF domain
SMARTSM003803.4E-20244313IPR001471AP2/ERF domain
PRINTSPR003671.7E-5245256IPR001471AP2/ERF domain
PRINTSPR003671.7E-5289309IPR001471AP2/ERF domain
CDDcd000181.52E-11360419No hitNo description
PfamPF008473.7E-10360411IPR001471AP2/ERF domain
SuperFamilySSF541719.81E-18360420IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.105.0E-18361419IPR001471AP2/ERF domain
SMARTSM003807.9E-31361425IPR001471AP2/ERF domain
PROSITE profilePS5103219.111361419IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010080Biological Processregulation of floral meristem growth
GO:0010492Biological Processmaintenance of shoot apical meristem identity
GO:0035265Biological Processorgan growth
GO:0048364Biological Processroot development
GO:0060772Biological Processleaf phyllotactic patterning
GO:0060774Biological Processauxin mediated signaling pathway involved in phyllotactic patterning
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 543 aa     Download sequence    Send to blast
MAPASNWLSF SLMSPMEMLR SSESDQSPFV PYDASSAASP HYFLDNFYAS NGWQTNPKSQ  60
VFFTDGEDQS KQQGQSDSPN LSPFVDPQSH TQHIPKLEDF LGDSSSMVRY SNSQTETQDS  120
SSLTHMYDQS STYFGGDHQQ QEDLKAITGF QAFSTNSGSE VEDSASMART TQHQQQLACA  180
EFGGHSIESN GNELGVYNSS CRTNALSLGV TTTQSSSDQK KAIVAVDNDG SKKIADTFGQ  240
RTSIYRGVTR HRWTGRYEAH LWDNSCRREG QARKGRQGGY DKEDKAARAY DLAALKYWGP  300
TATTNFPVMH XELILIFRMF FSTEKVSTYS KELEDMQHMT KQEFIASLRR KSSGFSRGAS  360
IYRGVTRHHQ QGRWQARIGR VAGNKDLYLG TFATEEEAAE AYDIAAIKFR GINAVTNFEM  420
NRYDVEAIGK SSLPVGGAAK RLKLSLEAEE QRPSVNHDQQ HPQCSIGSNI NFTSMQPVQS  480
IPCGIPYDAA AASTYYHHLF HQFQPNYHGA SDSAGLNPNI ATQMSMMPQQ PAEFYIWPNH  540
QSH
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.260300.0bud| root
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Detected in inflorescence and youg floral mersitems, and in stem procambial cells. In floral mersitems, mostly expressed in the central dome. Disappears progressively from sepal primordia, but accumulates in second, third and fourth whorl organ primordia. Later, confined to occasional patches in stamens and in petal before disparearing progressively from flowers. {ECO:0000269|PubMed:15988559}.
UniprotTISSUE SPECIFICITY: Expressed in roots, seedlings, hypocotyl, inflorescence, siliques, and pistils. Also detected at low levels in leaves. {ECO:0000269|PubMed:15988559, ECO:0000269|PubMed:16307362}.
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00504DAPTransfer from AT5G10510Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKJ7844592e-33KJ784459.1 Salvia miltiorrhiza AP8/EREBP Transcription Factors (WRI8) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008338468.20.0AP2-like ethylene-responsive transcription factor AIL6
RefseqXP_017178751.20.0AP2-like ethylene-responsive transcription factor AIL6
SwissprotQ52QU20.0AIL6_ARATH; AP2-like ethylene-responsive transcription factor AIL6
TrEMBLA0A498HV020.0A0A498HV02_MALDO; Uncharacterized protein
STRINGXP_008338468.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF48103149
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G10510.20.0AINTEGUMENTA-like 6
Publications ? help Back to Top
  1. Krizek BA
    Intronic sequences are required for AINTEGUMENTA-LIKE6 expression in Arabidopsis flowers.
    BMC Res Notes, 2015. 8: p. 556
    [PMID:26459062]
  2. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  3. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  4. Du Y,Scheres B
    PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714
    [PMID:29078398]