PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000314227
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MYB_related
Protein Properties Length: 1131aa    MW: 128782 Da    PI: 6.0467
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000314227genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding322.9e-1010541107146
                       TSSS-HHHHHHHHHHHHHTTTT....-HHHHHHHHT....TTS-HHHHHHHHHH CS
  Myb_DNA-binding    1 rgrWTteEdellvdavkqlGgg....tWktIartmg....kgRtlkqcksrwqk 46  
                       r+ WT eE+e+l+++v+ +++     +Wk+I +       k Rt+++++++w k
    MDP0000314227 1054 RLYWTREEEEKLKELVNSFPTTgkyrCWKKILENGRdvfhKDRTPNDLRNKWGK 1107
                       788*************************************************66 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.40.850.102.3E-10112353IPR001752Kinesin motor domain
SMARTSM001298.4E-11413356IPR001752Kinesin motor domain
SuperFamilySSF525408.78E-9313351IPR027417P-loop containing nucleoside triphosphate hydrolase
CDDcd013746.52E-14815348No hitNo description
PROSITE profilePS50067100.66315348IPR001752Kinesin motor domain
PfamPF002253.1E-8922348IPR001752Kinesin motor domain
PRINTSPR003808.1E-3691112IPR001752Kinesin motor domain
PRINTSPR003808.1E-36201218IPR001752Kinesin motor domain
PROSITE patternPS004110234245IPR019821Kinesin motor domain, conserved site
PRINTSPR003808.1E-36235253IPR001752Kinesin motor domain
PRINTSPR003808.1E-36298319IPR001752Kinesin motor domain
SuperFamilySSF579036.87E-6785843IPR011011Zinc finger, FYVE/PHD-type
Gene3DG3DSA:3.30.40.105.7E-6798843IPR013083Zinc finger, RING/FYVE/PHD-type
PROSITE profilePS500907.80510491109IPR017877Myb-like domain
SuperFamilySSF466898.22E-710511110IPR009057Homeodomain-like
SMARTSM007171.4E-510531111IPR001005SANT/Myb domain
PfamPF002496.4E-810551107IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.7E-810561107IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007018Biological Processmicrotubule-based movement
GO:0003677Molecular FunctionDNA binding
GO:0003777Molecular Functionmicrotubule motor activity
GO:0005524Molecular FunctionATP binding
GO:0008017Molecular Functionmicrotubule binding
Sequence ? help Back to Top
Protein Sequence    Length: 1131 aa     Download sequence    Send to blast
MASRTPGTPR AKKEKIVVLV CLRPLSKREE LAKEQVSWDC LGDNTIVYKP PPHERSAQST  60
SFTFDKVFGP GSTEAVYEEG VRNVALSSLM GINATIFAYG QSGSGKTYTM RRIMEKAVDD  120
IYNHMIKTPE REFAIKISGL EIYNENVRDL LNTESVGNLK LLDDPEKGIV VEKLVEEAAS  180
SHQHLRSLIG ICEAQREVGE TALNENSSRS HQIIRLTIES TVRESLDCRT SFVASLNFVD  240
LAGSERAPDT HADGVRLREG CHINLSLMTL TNVIRKLSQF GCSLFDLIIS AGKLSGXIPY  300
RDSKLTRILQ HSLGGNARTA IICTLSPALS HAEQSRNTLF FATQAKEVVS DKQLVKHLQK  360
QVAKLEAELY TLYPLRERIQ QMEMEMEDLR SERXXARSQA DELRHKLEVX VVSDKXLVKR  420
LQMEVLRRET EVPTVSREED LRIQKVLNQL ELPHPYVKKL IFCIGVLPAT FYAEELGGGD  480
RARNTMIXHS MRLSSFAPFT LNHEILRLEV LLVQLGEGPS RALEIXXQKE VLENHDRARN  540
TMIRHPMRLS SFAPFMLNRE ILKLEVLLAQ LGEGPSRALE IVLQKEVAWQ GLENQDAGET  600
FCNLQAEIKE THYTSSRPKE FEVGSLVPVN KXEIPRLHSQ GSAIANLEEQ FPKVQYFTDK  660
LVSLPCIQLL XLRFLEDLFR PREVTGDVLE QIKNEPVKHN IVPLLGCWQE DEAEVDGGFH  720
LEPGTSNAAS PDVSAVEYDH ISEHVFHVKV EHPADRYEKK AISDEAKELM DCHRETSDSG  780
AFRNGKIDVS ENRDFLGFLC SNGGQLLICN TSNCPFVFHQ NFLDSDLICY KKGKYYCPIC  840
SYSLAYENRL GEIEEKLRRK AVAFDEVFSG CTDGCTVNEQ MNARNENGYG CDCQFDDAQV  900
HNQFVGVEDN EIKEGTEFED EETAVEENSG XNEEDEGGKR AFVEXEDEIE NAELMQPESM  960
EVPSNTIVLS DTESPVVXKT MKKRQRVLPS FCLIPRNLML QILGLLPWNR KFQILGLLYW  1020
ARYSLNIKLS IVNQLFLLTC SSNLPLPRXR RRMRLYWTRE EEEKLKELVN SFPTTGKYRC  1080
WKKILENGRD VFHKDRTPND LRNKWGKMRV KGAVDHFLTL RENICSIRKM N
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1t5c_A4e-70113461326Centromeric protein E
1t5c_B4e-70113461326Centromeric protein E
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable plus end-directed motor protein that functions in the NACK-PQR (NPK1-NQK1/MEK1-NRK1) MAP kinase signaling pathway, which is essential for somatic cell cytokinesis, especially for the cell-plate formation and its expansion. Regulates the activity and the localization of NPK1 by association through the non-catalytic region of the kinase. {ECO:0000269|PubMed:11955449, ECO:0000269|PubMed:22006334}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: During the M phase of the cell cycle (at protein level). {ECO:0000269|PubMed:11955449}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028950255.10.0uncharacterized protein LOC103431402
SwissprotQ8S9500.0KN7A_TOBAC; Kinesin-like protein NACK1
TrEMBLA0A498HN640.0A0A498HN64_MALDO; Kinesin-like protein
STRINGXP_008361127.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF2282324
Publications ? help Back to Top
  1. Ito M, et al.
    G2/M-phase-specific transcription during the plant cell cycle is mediated by c-Myb-like transcription factors.
    Plant Cell, 2001. 13(8): p. 1891-905
    [PMID:11487700]
  2. Nishihama R, et al.
    Expansion of the cell plate in plant cytokinesis requires a kinesin-like protein/MAPKKK complex.
    Cell, 2002. 109(1): p. 87-99
    [PMID:11955449]
  3. Ishikawa M,Soyano T,Nishihama R,Machida Y
    The NPK1 mitogen-activated protein kinase kinase kinase contains a functional nuclear localization signal at the binding site for the NACK1 kinesin-like protein.
    Plant J., 2002. 32(5): p. 789-98
    [PMID:12472693]
  4. Sasabe M, et al.
    Phosphorylation of a mitotic kinesin-like protein and a MAPKKK by cyclin-dependent kinases (CDKs) is involved in the transition to cytokinesis in plants.
    Proc. Natl. Acad. Sci. U.S.A., 2011. 108(43): p. 17844-9
    [PMID:22006334]