PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000316055
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family E2F/DP
Protein Properties Length: 390aa    MW: 43204.3 Da    PI: 6.1449
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000316055genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP87.11.3e-27127210271
        E2F_TDP   2 keksLrlltqkflklleksee.givtlnevakeLvse.................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                    ++++Lr++++k   ++ek+e+ g++t+neva+eLv+e                 d+kn+rRR+YD+lNVL+a+++i+k +k+ei+wkg
  MDP0000316055 127 NGRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfadpsnavtspdqqqqdDEKNIRRRVYDALNVLMAMDIISK-DKKEIQWKG 210
                    789********...*****999********************************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0094044.0E-12538387IPR015648Transcription factor DP
Gene3DG3DSA:1.10.10.109.8E-46122215IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-33126210IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.6E-25128210IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.94E-20129211IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd144582.13E-42215324IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440741.26E-39216336No hitNo description
SMARTSM011381.4E-68217385IPR014889Transcription factor DP, C-terminal
PfamPF087816.7E-39218337IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 390 aa     Download sequence    Send to blast
MTGELFTNSH ISAEFFSQSR SVTVDHIPVV WCGVVGIRMG TRSQQQPGRE RAGQDDDEMA  60
GGQSVSMSGS VGSPSSRSEQ TMATPAGDNS FLRLNHPDVH GDDAGSQGAV GSKKKKRGQR  120
AVAGDKNGRG LRQFSMKVCE KVESKGRTTY NEVADELVAE FADPSNAVTS PDQQQQDDEK  180
NIRRRVYDAL NVLMAMDIIS KDKKEIQWKG LPRTSLNDIE ELKTERMGLR NRIEKKSAYL  240
QELEEQYVGL QNLIQRNEEL YHTGDAPSGG VALPFILVQA SFLLKTRPHA TVEVEISEDM  300
QLVHFDFNST PFELHDDNYV LKAMNFCNRQ QSDDATQNLT VDGGEGCSMS GMYQPQIPLA  360
SMNTPVRAPP MSPPRPGILK SRVKHEHHGQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B9e-35120215193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during the whole cell cycle. {ECO:0000269|PubMed:11669580}.
UniprotTISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankFQ3817571e-42FQ381757.1 Vitis vinifera clone SS0ABG85YD15.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008362813.10.0transcription factor-like protein DPB isoform X4
SwissprotQ9FNY21e-151DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A498JIJ40.0A0A498JIJ4_MALDO; Uncharacterized protein
TrEMBLA0A498KT320.0A0A498KT32_MALDO; Uncharacterized protein
STRINGXP_009351833.10.0(Pyrus x bretschneideri)
STRINGXP_008362811.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33213366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.11e-143Transcription factor DP