PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000321735

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

DBB

Protein Properties

Length: 187aa MW: 20499 Da PI: 7.5675

Description

DBB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000321735	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-B_box	21.2	6.2e-07	4	34	5	35
zf-B_box 5 kCpeHeekelqlfCedCqqllCedClleeHk 35 C+ +e+ +++ C ++ lC++C +e H MDP0000321735 4 QCDACEKAPAKVICCADEAALCAKCDVEVHA 34 7***************************994 PP
2	zf-B_box	19.3	2.4e-06	91	119	16	38
zf-B_box 16 lfCedCqqllCedClleeHkg......Ht 38 +fC +++ l+C+dC + +H+ H+ MDP0000321735 91 IFCVEDRALVCQDCDELIHSAnsrsanHQ 119 6******************5556666665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50119	8.802	1	47	IPR000315	B-box-type zinc finger
CDD	cd00021	6.53E-5	3	35	No hit	No description
SMART	SM00336	8.6E-6	4	47	IPR000315	B-box-type zinc finger
SMART	SM00336	0.011	85	123	IPR000315	B-box-type zinc finger
CDD	cd00021	0.00252	92	114	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005622	Cellular Component	intracellular
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 187 aa Download sequence Send to blast
MKIQCDACEK APAKVICCAD EAALCAKCDV EVHAANKLAS KNQRLLLECL SKSNKLPTCD 60 ICQCLKFQSR FVSLFLSHKH LVIPRTRQSF IFCVEDRALV CQDCDELIHS ANSRSANHQR 120 FLATGIRVAL STGCSNDTEP SXLEPPSSHS SHKIVSTKIP TPQASGISSP WGVXDLLQLS 180 DFESSDK

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.1717	1e-118	bud\| fruit\| leaf

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: High expression in leaves and lower in roots and flowers.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of seedling photomorphogenesis and light-regulated inhibition of hypocotyl elongation (PubMed:17605755, PubMed:18540109, PubMed:21685177). BBX24/STO and BBX25/STH function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression. BBX24/STO acts additively with BBX25/STH during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715). Functions as negative regulator of photomorphogenic UV-B responses by interacting with both COP1 and HY5 (PubMed:22410790). May act as a transcription factor in the salt-stress response (PubMed:12909688). {ECO:0000269\|PubMed:12909688, ECO:0000269\|PubMed:17605755, ECO:0000269\|PubMed:18540109, ECO:0000269\|PubMed:21685177, ECO:0000269\|PubMed:22410790, ECO:0000269\|PubMed:23624715}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian regulation with a peak before dawn. {ECO:0000269\|PubMed:17605755}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JQ027697	1e-113	JQ027697.1 Malus zumi STO mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028963367.1	1e-107	B-box zinc finger protein 24-like
Swissprot	Q96288	4e-56	BBX24_ARATH; B-box zinc finger protein 24
TrEMBL	A0A498J729	1e-105	A0A498J729_MALDO; Uncharacterized protein
STRING	XP_009342646.1	3e-96	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3438	31	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G06040.2	7e-56	DBB family protein

Link Out ? help Back to Top
Phytozome	MDP0000321735

Publications ? help Back to Top
Gangappa SN,Holm M,Botto JF Molecular interactions of BBX24 and BBX25 with HYH, HY5 HOMOLOG, to modulate Arabidopsis seedling development. Plant Signal Behav, 2014. [PMID:23733077] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Imtiaz M, et al. Identification and functional characterization of the BBX24 promoter and gene from chrysanthemum in Arabidopsis. Plant Mol. Biol., 2015. 89(1-2): p. 1-19 [PMID:26253592] Job N,Yadukrishnan P,Bursch K,Datta S,Johansson H Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains. Plant Physiol., 2018. 176(4): p. 2963-2976 [PMID:29439209]