PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000418900
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family WRKY
Protein Properties Length: 159aa    MW: 17428.7 Da    PI: 8.7352
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000418900genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY92.24.1e-29463159
                   ---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
           WRKY  1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59
                   ++Dgy+WrKYGqK+ ++++ pr+YY+C++a +Cpvkkkv++sae+p v++ tYegeHnh 
  MDP0000418900  4 VKDGYQWRKYGQKVTRDNPSPRAYYKCSFApSCPVKKKVQKSAENPCVLVATYEGEHNHM 63
                   58***************************99****************************5 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5081126.544165IPR003657WRKY domain
Gene3DG3DSA:2.20.25.807.1E-28265IPR003657WRKY domain
SuperFamilySSF1182901.57E-24365IPR003657WRKY domain
SMARTSM007742.4E-31464IPR003657WRKY domain
PfamPF031067.2E-24562IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 159 aa     Download sequence    Send to blast
MQIVKDGYQW RKYGQKVTRD NPSPRAYYKC SFAPSCPVKK KVQKSAENPC VLVATYEGEH  60
NHMHPESRAE VTLIAPVSPN QNQPPISVSP SMAKRSAPPT FSCDINRISP NTTMCPQETE  120
AATFQQFLVQ QMASSLTQDP NFTSALAAAI SGRISDHS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-211651477Probable WRKY transcription factor 4
2lex_A2e-211651477Probable WRKY transcription factor 4
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.257179e-79leaf
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.
UniProtTranscription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity). Modulates plant innate immunity against X.oryzae pv. oryzae (Xoo) (By similarity). {ECO:0000250|UniProtKB:Q6EPZ2, ECO:0000250|UniProtKB:Q6QHD1}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by biotic elicitors (e.g. fungal chitin oligosaccharide) (By similarity). Induced by pathogen infection (e.g. M.grisea and X.oryzae pv. oryzae (Xoo)) (PubMed:16528562). Accumulates after treatment with benzothiadiazole (BTH) and salicylic acid (SA) (By similarity). {ECO:0000250|UniProtKB:Q6EPZ2, ECO:0000269|PubMed:16528562}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB6273010.0AB627301.1 Malus x domestica mRNA, microsatellite: MEST165, clone: SAM01_21_E10.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017189732.11e-113probable WRKY transcription factor 40 isoform X1
SwissprotQ6IEK58e-48WRK76_ORYSI; WRKY transcription factor WRKY76
SwissprotQ9SK334e-48WRK60_ARATH; Probable WRKY transcription factor 60
TrEMBLA0A498HUB31e-112A0A498HUB3_MALDO; Uncharacterized protein
STRINGXP_008365552.11e-115(Malus domestica)
STRINGXP_008378959.11e-113(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF97334115
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G25000.12e-50WRKY DNA-binding protein 60
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Zhang Y, et al.
    Regulation of oncogene expression in T-DNA-transformed host plant cells.
    PLoS Pathog., 2015. 11(1): p. e1004620
    [PMID:25615824]
  4. Geilen K,Böhmer M
    Dynamic subnuclear relocalisation of WRKY40 in response to Abscisic acid in Arabidopsis thaliana.
    Sci Rep, 2015. 5: p. 13369
    [PMID:26293691]
  5. Geilen K,Böhmer M
    Dynamic subnuclear relocalization of WRKY40, a potential new mechanism of ABA-dependent transcription factor regulation.
    Plant Signal Behav, 2015. 10(11): p. e1106659
    [PMID:26479147]
  6. Lu K, et al.
    Overexpression of an Arabidopsis cysteine-rich receptor-like protein kinase, CRK5, enhances abscisic acid sensitivity and confers drought tolerance.
    J. Exp. Bot., 2016. 67(17): p. 5009-27
    [PMID:27406784]