PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000420192

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

bHLH

Protein Properties

Length: 275aa MW: 30572.7 Da PI: 9.9303

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000420192	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26	1.6e-08	187	227	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L MDP0000420192 187 ARHRRERISEKIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 227 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.294	178	227	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.2E-13	179	236	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.78E-11	180	232	No hit	No description
SuperFamily	SSF47459	4.32E-14	182	236	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.8E-14	184	233	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	7.3E-6	188	227	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010500	Biological Process	transmitting tissue development
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0048462	Biological Process	carpel formation
GO:2000012	Biological Process	regulation of auxin polar transport
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 275 aa Download sequence Send to blast
MDVDMLKSLS SSSAAGGDHH HHHMDMMTMM MQMQQQQHSP DHFCNDSYPN NNNPTFPEID 60 FNWVSNPNPN NLESISPLPM FHNPNPNAVP QQPTLLNPAL XSSVSFMGNP VQEPVTPRLI 120 KPSGISLTGL AVPSSTSPYE KRNSMAAMRE MIFRIAAMQP IQIDPEAVKP PKRRNVKISK 180 DPQSVAARHR RERISEKIRI LQRLVPGGTK MDTASMLDEA IHYVKFLKKQ VQTLERAGAD 240 RLDGVGFQGS GSQLGNVNYS SFRSQLVGSM QMLR*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed in the developing septum, transmitting tract and stigma. {ECO:0000269\|PubMed:17855426}.
Uniprot	TISSUE SPECIFICITY: Flowers, especially in gynoecium. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:17855426}.

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008340184.2	0.0	transcription factor HEC2
Swissprot	Q9FHA7	2e-45	HEC1_ARATH; Transcription factor HEC1
TrEMBL	M5VUU4	1e-124	M5VUU4_PRUPE; Uncharacterized protein
STRING	XP_008340184.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF651	34	141

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G67060.1	3e-48	bHLH family protein

Link Out ? help Back to Top
Phytozome	MDP0000420192

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Vercruyssen L, et al. ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development. Plant Cell, 2014. 26(1): p. 210-29 [PMID:24443518] Sparks EE,Benfey PN HEC of a job regulating stem cells. Dev. Cell, 2014. 28(4): p. 349-50 [PMID:24576420] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656] Gaillochet C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. Elife, 2018. [PMID:29058667]