PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000468411
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family NAC
Protein Properties Length: 87aa    MW: 10028.9 Da    PI: 10.4553
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000468411genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM38.43.8e-1226783894
            NAM 38 diykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevls 94
                   di+ +  +d+      +ekewyfFs+rd+ky++g+r+n a+ +gyWk tg dk++ +
  MDP0000468411 26 DINASPGSDMA---LYGEKEWYFFSSRDRKYPNGSRPNWAAGTGYWK-TGVDKHIGK 78
                   55555556664...23689***************************9.899999876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5100512.989187IPR003441NAC domain
SuperFamilySSF1019413.27E-123476IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 87 aa     Download sequence    Send to blast
MSVKYHHMIG FRAHFQQVVS RSVQDDINAS PGSDMALYGE KEWYFFSSRD RKYPNGSRPN  60
WAAGTGYWKT GVDKHIGKPR ALXIKKX
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A2e-16367666107NO APICAL MERISTEM PROTEIN
1ut4_B2e-16367666107NO APICAL MERISTEM PROTEIN
1ut7_A2e-16367666107NO APICAL MERISTEM PROTEIN
1ut7_B2e-16367666107NO APICAL MERISTEM PROTEIN
3swm_A1e-16367669110NAC domain-containing protein 19
3swm_B1e-16367669110NAC domain-containing protein 19
3swm_C1e-16367669110NAC domain-containing protein 19
3swm_D1e-16367669110NAC domain-containing protein 19
3swp_A1e-16367669110NAC domain-containing protein 19
3swp_B1e-16367669110NAC domain-containing protein 19
3swp_C1e-16367669110NAC domain-containing protein 19
3swp_D1e-16367669110NAC domain-containing protein 19
4dul_A2e-16367666107NAC domain-containing protein 19
4dul_B2e-16367666107NAC domain-containing protein 19
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.80391e-48bud| leaf| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in germinating seeds, roots, leaf veins, open flowers and silique stalks. {ECO:0000269|PubMed:27388337}.
UniprotTISSUE SPECIFICITY: Expressed in root cortex, root caps and sepals. Not detected in imbibed seeds. {ECO:0000269|PubMed:19176720}.
Functional Description ? help Back to Top
Source Description
UniProtMay be involved in regulation of seed germination under flooding. {ECO:0000269|PubMed:19176720}.
UniProtTranscriptional activator that positively regulates age-dependent senescence, dark-induced leaf senescence and stress-induced senescence. Regulates leaf senescence through the modulation of the expression of senescence-associated genes SGR1/NYE1, SAG113 and SAUR36/SAG201, which are involved in chlorophyll degradation, and abscisic acid (ABA) and auxin promotion of senescence, respectively. Promotes reactive oxygen species (ROS) production during age-dependent and stress-induced senescence. Regulates positively auxin-mediated responses in roots (PubMed:27388337). Stress-responsive NAC transcription factor involved in ABA-inducible leaf senescence signaling (PubMed:26518251). Required for normal seed development and morphology (PubMed:18849494). {ECO:0000269|PubMed:18849494, ECO:0000269|PubMed:26518251, ECO:0000269|PubMed:27388337}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By abscisic acid (ABA) (PubMed:26518251). Induced by salinity and osmotic stress, and during leaf senescence (PubMed:27388337). {ECO:0000269|PubMed:26518251, ECO:0000269|PubMed:27388337}.
UniProtINDUCTION: By low-oxygen stress. {ECO:0000269|PubMed:19176720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF1981295e-45KF198129.1 Malus hupehensis NAC domain protein (NAC143) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021829844.12e-25NAC domain-containing protein 2-like
SwissprotQ8H1151e-23NA102_ARATH; NAC domain-containing protein 102
SwissprotQ9CAR01e-23NAC32_ARATH; NAC transcription factor 32
TrEMBLA0A498KQ275e-30A0A498KQ27_MALDO; Uncharacterized protein
STRINGEMJ129509e-25(Prunus persica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G77450.15e-26NAC domain containing protein 32
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y
    Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress.
    Plant Cell, 2014. 26(12): p. 4656-79
    [PMID:25549671]
  3. Takasaki H, et al.
    SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence.
    Plant J., 2015. 84(6): p. 1114-23
    [PMID:26518251]
  4. Mahmood K,El-Kereamy A,Kim SH,Nambara E,Rothstein SJ
    ANAC032 Positively Regulates Age-Dependent and Stress-Induced Senescence in Arabidopsis thaliana.
    Plant Cell Physiol., 2016. 57(10): p. 2029-2046
    [PMID:27388337]
  5. Allu AD,Brotman Y,Xue GP,Balazadeh S
    Transcription factor ANAC032 modulates JA/SA signalling in response to Pseudomonas syringae infection.
    EMBO Rep., 2016. 17(11): p. 1578-1589
    [PMID:27632992]
  6. Mahmood K,Xu Z,El-Kereamy A,Casaretto JA,Rothstein SJ
    The Arabidopsis Transcription Factor ANAC032 Represses Anthocyanin Biosynthesis in Response to High Sucrose and Oxidative and Abiotic Stresses.
    Front Plant Sci, 2016. 7: p. 1548
    [PMID:27790239]
  7. Song L, et al.
    A transcription factor hierarchy defines an environmental stress response network.
    Science, 2017.
    [PMID:27811239]
  8. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]