PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000485895

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

HSF

Protein Properties

Length: 85aa MW: 9631.98 Da PI: 10.2853

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000485895	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	42	2.5e-13	17	58	40	90
THHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXX CS HSF_DNA-bind 40 vLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgk 90 +Lpk+Fk +nf+SF+ QLn+YgF kv+ ++ weF+++ F+ k MDP0000485895 17 LLPKHFKDNNFSSFILQLNTYGFIKVDPDR---------WEFANERFQGRK 58 79***********************999.........******8654 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00415	4.3E-5	1	66	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	5.2E-7	17	29	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	1.63E-10	17	56	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	3.5E-10	17	58	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	4.0E-14	17	56	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	5.2E-7	30	42	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 85 aa Download sequence Send to blast
MLGKASLFRT CTNSPGLLPK HFKDNNFSSF ILQLNTYGFI KVDPDRWEFA NERFQGRKRW 60 ATIIRAQGES EVAKFISDAT TRCG*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: DNA-binding capacity is reduced by HSBP in vitro. {ECO:0000269\|PubMed:20388662}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009361628.1	3e-19	PREDICTED: heat stress transcription factor A-2-like
Refseq	XP_009361629.1	3e-19	PREDICTED: heat stress transcription factor A-2-like
Swissprot	O81821	1e-16	HFA1B_ARATH; Heat stress transcription factor A-1b
TrEMBL	A0A498KFB6	2e-17	A0A498KFB6_MALDO; Uncharacterized protein
STRING	XP_009361628.1	1e-18	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1612	33	93

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G16820.2	5e-19	heat shock factor 3

Link Out ? help Back to Top
Phytozome	MDP0000485895

Publications ? help Back to Top
Hsu SF,Jinn TL AtHSBP functions in seed development and the motif is required for subcellular localization and interaction with AtHSFs. Plant Signal Behav, 2010. 5(8): p. 1042-4 [PMID:20657173] Bechtold U, et al. Arabidopsis HEAT SHOCK TRANSCRIPTION FACTORA1b overexpression enhances water productivity, resistance to drought, and infection. J. Exp. Bot., 2013. 64(11): p. 3467-81 [PMID:23828547] Guan Q,Yue X,Zeng H,Zhu J The protein phosphatase RCF2 and its interacting partner NAC019 are critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis. Plant Cell, 2014. 26(1): p. 438-53 [PMID:24415771]