PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000518442

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

NF-YC

Protein Properties

Length: 246aa MW: 27462.5 Da PI: 6.3679

Description

NF-YC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000518442	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NF-YC	176.3	3e-55	72	175	1	101
NF-YC 1 qlksfwekq...iekatdfknhelPlarikkilkadedvkmisaeaPvllskacelfileltlrswlhaeenkrrtlkksdiaaavtrtdifdflv 93 ql++fw +q i++++dfknh+lPlarikki+kadedv+misaeaPv++++ace+filelt+rsw+h+eenkrrtl+k+diaaa+trtdifdflv MDP0000518442 72 QLQKFWGEQhkeIDQTNDFKNHSLPLARIKKIMKADEDVRMISAEAPVIFARACEMFILELTMRSWNHTEENKRRTLQKNDIAAAITRTDIFDFLV 167 89**9998889******************************************************************************* PP NF-YC 94 divprdel 101 divpr++l MDP0000518442 168 DIVPREDL 175 ***987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47113	5.7E-34	54	166	IPR009072	Histone-fold
Gene3D	G3DSA:1.10.20.10	5.2E-38	86	158	IPR009072	Histone-fold
Pfam	PF00808	1.9E-21	94	157	IPR003958	Transcription factor CBF/NF-Y/archaeal histone domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046982	Molecular Function	protein heterodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 246 aa Download sequence Send to blast
MDQQGQGHGH PATMGVAGTA AQASYGVNPY GSVGMLQSPT QPAGPSAPSQ LAQHQLAYQH 60 IHQQQQQQLQ QQLQKFWGEQ HKEIDQTNDF KNHSLPLARI KKIMKADEDV RMISAEAPVI 120 FARACEMFIL ELTMRSWNHT EENKRRTLQK NDIAAAITRT DIFDFLVDIV PREDLKDEVL 180 ASIPRGGNLP VGXPSDGVPY YYMPPQHAPQ VGAPGNQNMY GQQTHAYIAQ PTWPHQQQQP 240 HEDIE*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5g49_B	7e-61	80	172	3	95	NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT C-3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	144	150	RRTLQKN

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.13270	0.0	bud\| fruit\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269\|PubMed:11250072}.

Functional Description ? help Back to Top
Source	Description
UniProt	Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008340921.2	0.0	nuclear transcription factor Y subunit C-3-like
Swissprot	Q9ZVL3	1e-76	NFYC3_ARATH; Nuclear transcription factor Y subunit C-3
TrEMBL	A0A498HGB7	0.0	A0A498HGB7_MALDO; Uncharacterized protein
STRING	XP_008340921.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1257	34	108

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G54830.3	2e-75	nuclear factor Y, subunit C3

Link Out ? help Back to Top
Phytozome	MDP0000518442

Publications ? help Back to Top
Hwang YH, et al. Functional conservation of rice OsNF-YB/YC and Arabidopsis AtNF-YB/YC proteins in the regulation of flowering time. Plant Cell Rep., 2016. 35(4): p. 857-65 [PMID:26754793] Liu X, et al. The NF-YC-RGL2 module integrates GA and ABA signalling to regulate seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 12768 [PMID:27624486] Myers ZA, et al. NUCLEAR FACTOR Y, Subunit C (NF-YC) Transcription Factors Are Positive Regulators of Photomorphogenesis in Arabidopsis thaliana. PLoS Genet., 2016. 12(9): p. e1006333 [PMID:27685091] Gnesutta N,Saad D,Chaves-Sanjuan A,Mantovani R,Nardini M Crystal Structure of the Arabidopsis thaliana L1L/NF-YC3 Histone-fold Dimer Reveals Specificities of the LEC1 Family of NF-Y Subunits in Plants. Mol Plant, 2017. 10(4): p. 645-648 [PMID:27871811] Tang Y, et al. Arabidopsis NF-YCs Mediate the Light-Controlled Hypocotyl Elongation via Modulating Histone Acetylation. Mol Plant, 2017. 10(2): p. 260-273 [PMID:27876642] Zhao H, et al. The Arabidopsis thaliana Nuclear Factor Y Transcription Factors. Front Plant Sci, 2016. 7: p. 2045 [PMID:28119722] Gnesutta N, et al. CONSTANS Imparts DNA Sequence Specificity to the Histone Fold NF-YB/NF-YC Dimer. Plant Cell, 2017. 29(6): p. 1516-1532 [PMID:28526714]