PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000537324
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MYB
Protein Properties Length: 226aa    MW: 25772 Da    PI: 7.2533
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000537324genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding54.92e-17956148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g WT+eEde+l+d+++ +G g+W++I++  g++R++k+c++rw+++l
    MDP0000537324  9 KGLWTKEEDEILLDYIRVHGRGRWNRIPKVTGLRRSGKSCRLRWLNHL 56
                     678*******************************************97 PP
2Myb_DNA-binding57.72.6e-1862107148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      rg +++eE++l+++++++lG++ W++Ia +++ gRt++q+k++w+++l
    MDP0000537324  62 RGDFSEEEEDLIIRLHNLLGNR-WSLIAGRVP-GRTDNQVKNYWNTHL 107
                      899*******************.*********.************996 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129416.83156IPR017930Myb domain
SuperFamilySSF466893.4E-307103IPR009057Homeodomain-like
SMARTSM007172.3E-15858IPR001005SANT/Myb domain
PfamPF002491.6E-15956IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.9E-231063IPR009057Homeodomain-like
CDDcd001675.03E-121256No hitNo description
PROSITE profilePS5129426.22557111IPR017930Myb domain
SMARTSM007176.5E-1761109IPR001005SANT/Myb domain
PfamPF002492.3E-1762107IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.2E-2564111IPR009057Homeodomain-like
CDDcd001674.05E-1265107No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 226 aa     Download sequence    Send to blast
MEAEYEYKKG LWTKEEDEIL LDYIRVHGRG RWNRIPKVTG LRRSGKSCRL RWLNHLSPNV  60
KRGDFSEEEE DLIIRLHNLL GNRWSLIAGR VPGRTDNQVK NYWNTHLYKK LNAIKKQQTS  120
GKVAVVSTSK TTTHSSSAAQ ELAGDKLVHQ HKMLKAPDSD SNSVTKSNDQ NPNMDIVAAE  180
DSNAEEEEIE WMAKHCTELL SCSSYGNMIS WDTVEFLQGY PLDLL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C7e-28611124128MYB TRANSFORMING PROTEIN
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: First expressed in leaf primordia. Later confined to developing trichome cells where it persists at high levels throughout all stages of trichome development. {ECO:0000269|PubMed:11437443, ECO:0000269|PubMed:15728674}.
UniprotTISSUE SPECIFICITY: Expressed in roots, seed coats, leaves, stems and flowers. Detected specifically in trichomes, and in the cell division and differentiation zone of the root. {ECO:0000269|PubMed:11437443}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator, when associated with BHLH2/EGL3/MYC146 or BHLH12/MYC1. Regulates the epidermal cell fate specification. Mediates the formation of columellae and accumulation of mucilages on seed coats. Controls the elongation of epidermal cells positively in roots but negatively in stems, leading to the promotion of primary roots elongation and repression of leaves and stems elongation, respectively. Ovoids ectopic root-hair formation, probably by inducing GL2 in roots. Controls trichome initiation and branching. {ECO:0000269|PubMed:11437443, ECO:0000269|PubMed:15361138, ECO:0000269|PubMed:15668208, ECO:0000269|PubMed:15728674}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008389647.11e-168transcription factor WER-like
SwissprotQ962763e-63MYB23_ARATH; Transcription factor MYB23
TrEMBLA0A498IER51e-165A0A498IER5_MALDO; Uncharacterized protein
STRINGXP_008389647.11e-168(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF3134817
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G14750.11e-62myb domain protein 66
Publications ? help Back to Top
  1. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  2. Yu D, et al.
    RPN1a, a subunit of the 26S proteasome, controls trichome development in Arabidopsis.
    Plant Physiol. Biochem., 2015. 88: p. 82-8
    [PMID:25676129]
  3. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  4. Kohanová J, et al.
    Root hair abundance impacts cadmium accumulation in Arabidopsis thaliana shoots.
    Ann. Bot., 2018. 122(5): p. 903-914
    [PMID:29394308]