PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000664576

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

DBB

Protein Properties

Length: 244aa MW: 26662.9 Da PI: 4.7158

Description

DBB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000664576	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-B_box	20.6	9.4e-07	4	34	5	35
zf-B_box 5 kCpeHeekelqlfCedCqqllCedClleeHk 35 C+ +e+ +++ C ++ lC++C +e H MDP0000664576 4 QCDACEKAPAKVICCADEAALCAKCDVEVHA 34 7***************************994 PP
2	zf-B_box	29.2	1.9e-09	55	96	2	37
zf-B_box 2 eerkCpeHeekelqlfCedCqqllCedClleeHkg......H 37 + ++C+ +++k + +fC +++ l+C+dC + +H+ H MDP0000664576 55 KLPTCDICQDKAAFIFCVEDRALVCQDCDELIHSXnsrsanH 96 789******************************545566666 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50119	8.802	1	47	IPR000315	B-box-type zinc finger
CDD	cd00021	7.29E-6	3	35	No hit	No description
SMART	SM00336	8.6E-6	4	47	IPR000315	B-box-type zinc finger
SMART	SM00336	1.3E-13	54	101	IPR000315	B-box-type zinc finger
PROSITE profile	PS50119	9.229	54	101	IPR000315	B-box-type zinc finger
Pfam	PF00643	2.3E-8	55	97	IPR000315	B-box-type zinc finger
CDD	cd00021	2.00E-7	59	100	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009640	Biological Process	photomorphogenesis
GO:0009651	Biological Process	response to salt stress
GO:0048573	Biological Process	photoperiodism, flowering
GO:0080167	Biological Process	response to karrikin
GO:0090351	Biological Process	seedling development
GO:1902448	Biological Process	positive regulation of shade avoidance
GO:0005634	Cellular Component	nucleus
GO:0003712	Molecular Function	transcription cofactor activity
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 244 aa Download sequence Send to blast
MKIQCDACEK APAKVICCAD EAALCAKCDV EVHAANKLAS KNQRLLLECL SKSNKLPTCD 60 ICQDKAAFIF CVEDRALVCQ DCDELIHSXN SRSANHQRFL ATGIRVALST GCSNDTEPSS 120 LEPPSSHSSH KIVSTKIPTP QASGISSPWG VDDLLQLSDF ESSDKKESFE FGELEWIADM 180 GVFGEEQFPQ KAMAAVAEVP KLLVSQSTNF TSYRPAKLNN PYKKPRIEML EDDDDHFTVP 240 DLG*

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.1717	0.0	bud\| fruit\| leaf

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: High expression in leaves and lower in roots and flowers.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of seedling photomorphogenesis and light-regulated inhibition of hypocotyl elongation (PubMed:17605755, PubMed:18540109, PubMed:21685177). BBX24/STO and BBX25/STH function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression. BBX24/STO acts additively with BBX25/STH during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715). Functions as negative regulator of photomorphogenic UV-B responses by interacting with both COP1 and HY5 (PubMed:22410790). May act as a transcription factor in the salt-stress response (PubMed:12909688). {ECO:0000269\|PubMed:12909688, ECO:0000269\|PubMed:17605755, ECO:0000269\|PubMed:18540109, ECO:0000269\|PubMed:21685177, ECO:0000269\|PubMed:22410790, ECO:0000269\|PubMed:23624715}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian regulation with a peak before dawn. {ECO:0000269\|PubMed:17605755}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JQ027697	0.0	JQ027697.1 Malus zumi STO mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028963367.1	1e-179	B-box zinc finger protein 24-like
Swissprot	Q96288	1e-89	BBX24_ARATH; B-box zinc finger protein 24
TrEMBL	A0A498J729	1e-178	A0A498J729_MALDO; Uncharacterized protein
STRING	XP_009342646.1	1e-160	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3438	31	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G06040.1	7e-89	DBB family protein

Link Out ? help Back to Top
Phytozome	MDP0000664576

Publications ? help Back to Top
Gangappa SN,Holm M,Botto JF Molecular interactions of BBX24 and BBX25 with HYH, HY5 HOMOLOG, to modulate Arabidopsis seedling development. Plant Signal Behav, 2014. [PMID:23733077] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Imtiaz M, et al. Identification and functional characterization of the BBX24 promoter and gene from chrysanthemum in Arabidopsis. Plant Mol. Biol., 2015. 89(1-2): p. 1-19 [PMID:26253592] Job N,Yadukrishnan P,Bursch K,Datta S,Johansson H Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains. Plant Physiol., 2018. 176(4): p. 2963-2976 [PMID:29439209]