PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000823458
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MYB
Protein Properties Length: 291aa    MW: 32932 Da    PI: 4.6593
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000823458genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding55.41.4e-173582148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g+WT+eEd +l d+v+ +G g+W++ a + g++Rt+k+c++rw++yl
    MDP0000823458 35 KGPWTAEEDSILNDYVNIHGEGRWNSLACHAGLKRTGKSCRLRWLNYL 82
                     79********************************************97 PP
2Myb_DNA-binding47.73.6e-1588131146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      rg+ T +E++++++++ ++G++ W++Ia++++ gRt++++k++w++
    MDP0000823458  88 RGNITLQEQLIILQLHSRWGNR-WSKIAEYLP-GRTDNEIKNYWRT 131
                      7899******************.*********.***********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129415.7083082IPR017930Myb domain
SuperFamilySSF466891.65E-3032129IPR009057Homeodomain-like
SMARTSM007172.1E-133484IPR001005SANT/Myb domain
PfamPF002491.1E-153582IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.607.5E-233689IPR009057Homeodomain-like
CDDcd001671.09E-103782No hitNo description
PROSITE profilePS5129422.3683137IPR017930Myb domain
SMARTSM007171.7E-1387135IPR001005SANT/Myb domain
PfamPF002495.5E-1488131IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.1E-2190136IPR009057Homeodomain-like
CDDcd001672.38E-1092131No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009651Biological Processresponse to salt stress
GO:0009723Biological Processresponse to ethylene
GO:0009737Biological Processresponse to abscisic acid
GO:0009751Biological Processresponse to salicylic acid
GO:0016036Biological Processcellular response to phosphate starvation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0046686Biological Processresponse to cadmium ion
GO:0005634Cellular Componentnucleus
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0005516Molecular Functioncalmodulin binding
Sequence ? help Back to Top
Protein Sequence    Length: 291 aa     Download sequence    Send to blast
MDINNVHDQM RSARYGSLAA AATHDQPIEG LDLRKGPWTA EEDSILNDYV NIHGEGRWNS  60
LACHAGLKRT GKSCRLRWLN YLRPNVQRGN ITLQEQLIIL QLHSRWGNRW SKIAEYLPGR  120
TDNEIKNYWR TRVQKQAKQL KCDVNSKQFQ DAMRYVWIPR LIERIGSLPE AVPEQPSTCI  180
TTTSESECQY LVDPNFVPET SXSTSSESYD QVQVCSIPAD PTSSGDEFMT YPSSGQYGSE  240
NGSGCSQNGI NSDIDGFEQS NYWSTGGDTS VENLWTEENI WFLQQQLSDD *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C3e-262613718128MYB TRANSFORMING PROTEIN
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Highly expressed in leaves. Expressed in roots and shoots. Expressed at low levels in flowers. {ECO:0000269|PubMed:22301384}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in abiotic stress responses. Plays a regulatory role in tolerance to salt, cold, and drought stresses. Regulates positively the expression of genes involved in proline synthesis and transport, and genes involved in reactive oxygen species (ROS) scavenging such as peroxidase, superoxide dismutase and catalase during salt stress. Transactivates stress-related genes, including LEA3, RAB16A and DREB2A during salt stress. {ECO:0000269|PubMed:22301384}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by salt, cold and osmotic stresses, and abscisic acid (ABA). Down-regulated by salicylic acid (SA). {ECO:0000269|PubMed:22301384}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008343185.20.0transcription factor MYB108-like
SwissprotQ10MB42e-79MYB2_ORYSJ; Transcription factor MYB2
TrEMBLA0A498HAA40.0A0A498HAA4_MALDO; Uncharacterized protein
STRINGXP_008343185.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF87534125
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G47190.11e-75myb domain protein 2
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang A,Dai X,Zhang WH
    A R2R3-type MYB gene, OsMYB2, is involved in salt, cold, and dehydration tolerance in rice.
    J. Exp. Bot., 2012. 63(7): p. 2541-56
    [PMID:22301384]
  3. Chen X, et al.
    The NAC family transcription factor OsNAP confers abiotic stress response through the ABA pathway.
    Plant Cell Physiol., 2014. 55(3): p. 604-19
    [PMID:24399239]
  4. Lv Y, et al.
    New insights into the genetic basis of natural chilling and cold shock tolerance in rice by genome-wide association analysis.
    Plant Cell Environ., 2016. 39(3): p. 556-70
    [PMID:26381647]
  5. Hong Y,Zhang H,Huang L,Li D,Song F
    Overexpression of a Stress-Responsive NAC Transcription Factor Gene ONAC022 Improves Drought and Salt Tolerance in Rice.
    Front Plant Sci, 2016. 7: p. 4
    [PMID:26834774]