PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000825749

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

bHLH

Protein Properties

Length: 225aa MW: 25014.2 Da PI: 5.4401

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000825749	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	33.3	8.7e-11	70	117	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 a+ rE+ RR+r+N++f eL +l + +K +Ka+iL Av+ +++L MDP0000825749 70 AKACREKLRRERLNDRFVELSGVLEPG---XXPKTDKAAILDDAVRVLNQL 117 6778********************8...8***************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.487	66	117	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.5E-8	70	117	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	9.22E-9	70	122	No hit	No description
SMART	SM00353	5.7E-10	72	123	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	7.3E-11	72	139	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.15E-12	72	140	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 225 aa Download sequence Send to blast
MGEWIEYLDY IDETQPTDFL WPNDTPSFGD FEFSAVDVPA AAASSASQSQ EKECPRKRGR 60 TDSCSGGSGA KACREKLRRE RLNDRFVELS GVLEPGXXPK TDKAAILDDA VRVLNQLRAE 120 AQELTETNQK LLEEVKSLKA EKNELRXEKL VLKADKERLE QQLKGMAISP SGFVPTHPAV 180 PAAYHPGANK MAVYPSYSLV PMWHYIPPSX RDTSRDHELR PPAA*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	54	60	PRKRGRT

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.11570	0.0	bud\| cell culture\| fruit

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00102	PBM	Transfer from AT4G14410	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008351308.2	1e-163	transcription factor bHLH104-like
Swissprot	Q8L467	2e-82	BH104_ARATH; Transcription factor bHLH104
TrEMBL	A0A251QS62	1e-137	A0A251QS62_PRUPE; Uncharacterized protein
TrEMBL	M5XEQ1	1e-137	M5XEQ1_PRUPE; Uncharacterized protein
STRING	XP_008351308.1	1e-162	(Malus domestica)
STRING	XP_008391189.1	1e-162	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8179	25	37

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.2	3e-84	bHLH family protein

Link Out ? help Back to Top
Phytozome	MDP0000825749

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]