PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000929655
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ARF
Protein Properties Length: 565aa    MW: 62812.3 Da    PI: 6.2077
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000929655genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B369.64.1e-2269169198
                    EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSE CS
             B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrse 89 
                    f+k+lt sd++++g +++ +++a+++       ++++ +  +l+  d++g++W +++i+r++++r++lt+GW+ Fv++++L +gD ++F   + ++
  MDP0000929655  69 FCKTLTASDTSTHGGFSVLRRHADDClppldmtQQPPWQ--ELVASDLHGNEWHFRHIFRGQPRRHLLTTGWSVFVSSKKLVAGDAFIFL--RGEN 160
                    99****************************975444444..8************************************************..4499 PP

                    E..EEEEE- CS
             B3  90 felvvkvfr 98 
                    +el+v+v+r
  MDP0000929655 161 GELRVGVRR 169
                    99*****97 PP
2Auxin_resp106.72.6e-35195277183
     Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                    a+ha++t++ F+v+Y+Pr+s+seF v+v+k+ +a ++k+svGmRfkm+fe+e+++err+sGt+vgv d     W nS+WrsLk
  MDP0000929655 195 ASHAIATGTLFSVFYKPRTSRSEFLVSVNKYIEARSQKLSVGMRFKMRFEGEEVPERRFSGTIVGVGDNTAPGWANSEWRSLK 277
                    789*******************************************************************99*********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.96E-4358198IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.104.2E-4065184IPR015300DNA-binding pseudobarrel domain
CDDcd100172.44E-2067169No hitNo description
PfamPF023624.4E-2069169IPR003340B3 DNA binding domain
SMARTSM010192.9E-2069171IPR003340B3 DNA binding domain
PROSITE profilePS5086311.1869171IPR003340B3 DNA binding domain
PfamPF065071.3E-33195277IPR010525Auxin response factor
PfamPF023095.2E-7489564IPR033389AUX/IAA domain
PROSITE profilePS5174524.683496564IPR000270PB1 domain
SuperFamilySSF542773.38E-9498564No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009733Biological Processresponse to auxin
GO:0010150Biological Processleaf senescence
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0042802Molecular Functionidentical protein binding
Sequence ? help Back to Top
Protein Sequence    Length: 565 aa     Download sequence    Send to blast
MHQGSEQQMP SFNLPSKILC KVVNVQLRAE PETDEVYAQV TLLPEADQSE VTSPDPPLPE  60
TPQCTVHSFC KTLTASDTST HGGFSVLRRH ADDCLPPLDM TQQPPWQELV ASDLHGNEWH  120
FRHIFRGQPR RHLLTTGWSV FVSSKKLVAG DAFIFLRGEN GELRVGVRRL MRQPSNMPSS  180
VISSHSMHLG VLATASHAIA TGTLFSVFYK PRTSRSEFLV SVNKYIEARS QKLSVGMRFK  240
MRFEGEEVPE RRFSGTIVGV GDNTAPGWAN SEWRSLKVQW DEPSSILRPD RVSPWDLEPL  300
VATTPQNSQP ALRNKRARPP VLPSPSPDLS ALGEWKSKAE SPXAFSYSDS QRGRDIYPSP  360
KYNSASKPNS LCFTGNNSLA AVSGNSMFWP NRVDGVTEPF SPVMNKDCGE RRQSTGNGCR  420
LFGIQLLENS NLEETSPVVT VSGKLGDTLP VSSFDAESDQ HSEPSNLNRS DLPSGSCDAE  480
KSCLRSPQES QSRQIRSCTK VHMQGIAVGR AVDLTRFERY EDLLKKLEEM FDIEGELCGS  540
TKKWQVVYTD DEDDMMMVGD DPWQ*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A0.0130056355Auxin response factor 1
4ldw_A0.0130056355Auxin response factor 1
4ldw_B0.0130056355Auxin response factor 1
4ldx_A0.0130056355Auxin response factor 1
4ldx_B0.0130056355Auxin response factor 1
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in the sepals and carpels of young flower buds. At stage 10 of flower development, expression in the carpels becomes restricted to the style. Also expressed in anthers and filaments. At stage 13, expressed in the region at the top of the pedicel, including the abscission zone. {ECO:0000269|PubMed:16176952}.
UniprotTISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269|PubMed:10476078}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16176952}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00097PBMTransfer from AT1G59750Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008378943.20.0auxin response factor 1
RefseqXP_008378944.20.0auxin response factor 1
SwissprotQ8L7G00.0ARFA_ARATH; Auxin response factor 1
TrEMBLM5XJV30.0M5XJV3_PRUPE; Auxin response factor
STRINGXP_008378943.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF68022638
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G59750.40.0auxin response factor 1
Publications ? help Back to Top
  1. Montesinos JC,Pastor-Cantizano N,Robinson DG,Marcote MJ,Aniento F
    Arabidopsis p24δ5 and p24δ9 facilitate Coat Protein I-dependent transport of the K/HDEL receptor ERD2 from the Golgi to the endoplasmic reticulum.
    Plant J., 2014. 80(6): p. 1014-30
    [PMID:25312353]
  2. Marais C, et al.
    The Qb-SNARE Memb11 interacts specifically with Arf1 in the Golgi apparatus of Arabidopsis thaliana.
    J. Exp. Bot., 2015. 66(21): p. 6665-78
    [PMID:26208648]
  3. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  4. Zhang M,Hu X,Zhu M,Xu M,Wang L
    Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    Sci Rep, 2017. 7(1): p. 1395
    [PMID:28469131]