PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MELO3C010929P1

Organism

Cucumis melo

Taxonomic ID

3656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 462aa MW: 47576.6 Da PI: 8.722

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C010929P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.3	1.3e-05	63	85	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H MELO3C010929P1 63 FVCEICNKGFQRDQNLQLHRRGH 85 89*******************88 PP
2	zf-C2H2	15.9	3.7e-05	139	161	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC+ C+k + +s+ k H++t+ MELO3C010929P1 139 WKCERCSKKYAVQSDWKAHMKTC 161 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.15E-6	62	85	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.5E-5	62	85	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.017	63	85	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	63	85	IPR007087	Zinc finger, C2H2
Pfam	PF12171	7.2E-5	63	85	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	65	85	IPR007087	Zinc finger, C2H2
SMART	SM00355	96	104	134	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	1.15E-6	134	160	No hit	No description
SMART	SM00355	77	139	159	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 462 aa Download sequence Send to blast
MVSAESNSPT AMVTASSPPA VDEVEIIDTV TPAKKKRNLP GMPDPTAEVI ALSPKSLLAT 60 NRFVCEICNK GFQRDQNLQL HRRGHNLPWK LRQRTSNEIR KRVYVCPEPS CVHHNPARAL 120 GDLTGIKKHF SRKHCEKKWK CERCSKKYAV QSDWKAHMKT CGTREYKCDC GTLFSRRDSF 180 ITHRAFCDAL AFASSDTNVI AAAAAAVATA VVASSPLATV PVSPGLSIQS SEPPDIPMGP 240 PPLTPAATSL TSAVASTVNK NSPTNGGGAS FFAGVFSSSP PTVTSAPPNP PHQLTTGVNR 300 SDGGNDPSTT AIEPTSLSLS TSLFLSCRAS ASSGSTSASS IFQDHTPHYS LSPQPAAMSA 360 TALLQKAAQM GVTSSNASSL LRASGLSLSQ SPGPAISMTA GLGLGFGNEP TTRDLLGLGM 420 GGGGGGGGGV SGNGISALFT SFDGCDVETA SPYGGGGSNG L*

Sequence ? help Back to Top

Protein Sequence Length: 462 aa Download sequence Send to blast

MVSAESNSPT AMVTASSPPA VDEVEIIDTV TPAKKKRNLP GMPDPTAEVI ALSPKSLLAT  60
NRFVCEICNK GFQRDQNLQL HRRGHNLPWK LRQRTSNEIR KRVYVCPEPS CVHHNPARAL  120
GDLTGIKKHF SRKHCEKKWK CERCSKKYAV QSDWKAHMKT CGTREYKCDC GTLFSRRDSF  180
ITHRAFCDAL AFASSDTNVI AAAAAAVATA VVASSPLATV PVSPGLSIQS SEPPDIPMGP  240
PPLTPAATSL TSAVASTVNK NSPTNGGGAS FFAGVFSSSP PTVTSAPPNP PHQLTTGVNR  300
SDGGNDPSTT AIEPTSLSLS TSLFLSCRAS ASSGSTSASS IFQDHTPHYS LSPQPAAMSA  360
TALLQKAAQM GVTSSNASSL LRASGLSLSQ SPGPAISMTA GLGLGFGNEP TTRDLLGLGM  420
GGGGGGGGGV SGNGISALFT SFDGCDVETA SPYGGGGSNG L*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-32	136	190	4	58	Zinc finger protein JACKDAW
5b3h_F	2e-32	136	190	4	58	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681823	0.0	LN681823.1 Cucumis melo genomic scaffold, anchoredscaffold00014.
GenBank	LN713257	0.0	LN713257.1 Cucumis melo genomic chromosome, chr_3.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008444696.1	0.0	PREDICTED: protein indeterminate-domain 1-like
Swissprot	Q9SCQ6	1e-121	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A1S3BBP7	0.0	A0A1S3BBP7_CUCME; protein indeterminate-domain 1-like
STRING	XP_008444696.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2218	32	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-106	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]