PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C011837P1
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family C2H2
Protein Properties Length: 379aa    MW: 43589.5 Da    PI: 9.6986
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C011837P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.0005179101323
                     ET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                     C+   Cgk+F +   L++H   H
  MELO3C011837P1  79 CSyeGCGKTFIDAGALRKHSHIH 101
                     77779**************7766 PP
2zf-C2H216.42.5e-05106130123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     y+C+   Cgk F ++s LkrH   H
  MELO3C011837P1 106 YVCHyeGCGKKFLDSSKLKRHFLIH 130
                     9********************8877 PP
3zf-C2H221.75.4e-07136160123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     ++Cp   Cgk Fs   nL++H++tH
  MELO3C011837P1 136 FVCPheGCGKAFSLDFNLRSHMKTH 160
                     89**********************9 PP
4zf-C2H218.84.3e-06166190123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     + Cp  dCgk+F + + Lk+Hi +H
  MELO3C011837P1 166 HICPyaDCGKRFAHEYKLKNHITSH 190
                     68*********************96 PP
5zf-C2H213.80.00017229254123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     y Cp   C k + + + Lk H+r+ H
  MELO3C011837P1 229 YACPyeGCEKAYIHEYKLKLHLRReH 254
                     89**********************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.609.4E-1472103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.003277101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.78377106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576673.17E-880130No hitNo description
Gene3DG3DSA:3.30.160.602.4E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0024106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.921106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576673.03E-14117170No hitNo description
Gene3DG3DSA:3.30.160.603.6E-20127160IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003553.1E-4136160IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.695136165IPR007087Zinc finger, C2H2
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
SuperFamilySSF576675.62E-5160193No hitNo description
Gene3DG3DSA:3.30.160.601.2E-8161192IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0013166190IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.097166195IPR007087Zinc finger, C2H2
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.2E-9223252IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576679.29E-6224252No hitNo description
SMARTSM003550.0089229254IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.328229256IPR007087Zinc finger, C2H2
PROSITE patternPS000280231254IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 379 aa     Download sequence    Send to blast
METHFNHNLF DRRPIVKNKS PPVKWIKEWV PQDVVATGGK CFLLKWVTED TLKALKEKAK  60
QSEAPEPEPE PTTEVLFLCS YEGCGKTFID AGALRKHSHI HGERQYVCHY EGCGKKFLDS  120
SKLKRHFLIH TGERDFVCPH EGCGKAFSLD FNLRSHMKTH SQENYHICPY ADCGKRFAHE  180
YKLKNHITSH HEKNVTAEVV KYTPPSEKQT KVSKPSGGAY ASASSDRPYA CPYEGCEKAY  240
IHEYKLKLHL RREHPGHLVE DNGNAQHNGE NEVEASDQDV YGGKRANVKN QKQNKPKPNL  300
KLPPSKISQR KGTTPSPAPM SVVKKSWPVK EENYEEEDSE ETRRRRTVRT WRRDGDMLKT  360
KKMMRKQNMK IKIHKNGY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C3e-35701902119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818960.0LN681896.1 Cucumis melo genomic scaffold, anchoredscaffold00016.
GenBankLN7132640.0LN713264.1 Cucumis melo genomic chromosome, chr_10.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008445997.10.0PREDICTED: uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L31e-153YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A1S3BE040.0A0A1S3BE04_CUCME; uncharacterized zinc finger protein At4g06634
STRINGXP_008445997.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-144C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]