PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C016876P1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family C2H2
Protein Properties Length: 287aa    MW: 33291.5 Da    PI: 10.3911
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C016876P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.22.9e-054769123
                    EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                    + C++C+k F r  nL+ H r H
  MELO3C016876P1 47 FICEICKKGFQRDQNLQLHRRGH 69
                    89*******************88 PP

2zf-C2H213.50.00022123145123
                     EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                     +kC++C+k++  +s+ k H + +
  MELO3C016876P1 123 WKCEKCSKRYAVQSDWKAHSKIC 145
                     58*****************9876 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576673.95E-64669No hitNo description
Gene3DG3DSA:3.30.160.603.9E-54669IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.054769IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.5334769IPR007087Zinc finger, C2H2
PROSITE patternPS0002804969IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.1E-4111144IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.95E-6118143No hitNo description
SMARTSM00355130123143IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 287 aa     Download sequence    Send to blast
MDRCFDLSCV FKLLCNIKKE KSLNFESDPE AEVIALSPKS LLATNRFICE ICKKGFQRDQ  60
NLQLHRRGHN LPWKLKQRGN KEVRKKVYVC PELTCVHHHP SRALGDLTGI KKHFCRKHGE  120
KKWKCEKCSK RYAVQSDWKA HSKICGTREY RCDCGTLFSR RDSFITHRAF CNALAQESTN  180
FNNNPTPKLT SHLFPSINFP LKFEHQDPFF FSLLLFLLPL LLIKTLVTLL LQSVRVIFLL  240
LLALHGKLIT TTTAIIIHVQ LKLLHFSITW LVLKRLPHLK KLLMGY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C3e-34119184372Zinc finger protein JACKDAW
5b3h_F3e-34119184372Zinc finger protein JACKDAW
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
17385KLKQRGNKEVRKK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818610.0LN681861.1 Cucumis melo genomic scaffold, anchoredscaffold00029.
GenBankLN7132610.0LN713261.1 Cucumis melo genomic chromosome, chr_7.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008452730.11e-137PREDICTED: protein indeterminate-domain 7-like
RefseqXP_008452731.11e-137PREDICTED: protein indeterminate-domain 7-like
RefseqXP_016901351.11e-137PREDICTED: protein indeterminate-domain 7-like
SwissprotQ9ZWA61e-103IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A1S3BVB61e-136A0A1S3BVB6_CUCME; protein indeterminate-domain 7-like
STRINGXP_008452730.11e-137(Cucumis melo)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G03840.11e-105C2H2 family protein
Publications ? help Back to Top
  1. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]