PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MELO3C016876P2

Organism

Cucumis melo

Taxonomic ID

3656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 322aa MW: 36712.2 Da PI: 10.4829

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C016876P2	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16	3.3e-05	82	104	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C++C+k F r nL+ H r H MELO3C016876P2 82 FICEICKKGFQRDQNLQLHRRGH 104 89*******************88 PP
2	zf-C2H2	13.3	0.00025	158	180	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k++ +s+ k H + + MELO3C016876P2 158 WKCEKCSKRYAVQSDWKAHSKIC 180 58*****************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	4.77E-6	81	104	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.5E-5	81	104	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.05	82	104	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.533	82	104	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	84	104	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	1.3E-4	146	179	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	4.77E-6	153	178	No hit	No description
SMART	SM00355	130	158	178	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 322 aa Download sequence Send to blast
MVDENLSVLT CASGETVTRT EISTTTTPMY SHQSSSSINQ PTPPLPPLPP PSKKKRNLPG 60 NPDPEAEVIA LSPKSLLATN RFICEICKKG FQRDQNLQLH RRGHNLPWKL KQRGNKEVRK 120 KVYVCPELTC VHHHPSRALG DLTGIKKHFC RKHGEKKWKC EKCSKRYAVQ SDWKAHSKIC 180 GTREYRCDCG TLFSRRDSFI THRAFCNALA QESTNFNNNP TPKLTSHLFP SINFPLKFEH 240 QDPFFFSLLL FLLPLLLIKT LVTLLLQSVR VIFLLLLALH GKLITTTTAI IIHVQLKLLH 300 FSITWLVLKR LPHLKKLLMG Y*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	4e-35	154	219	3	72	Zinc finger protein JACKDAW
5b3h_F	4e-35	154	219	3	72	Zinc finger protein JACKDAW
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	108	120	KLKQRGNKEVRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269\|PubMed:17785527, ECO:0000269\|PubMed:21935722, ECO:0000269\|PubMed:24821766, ECO:0000269\|PubMed:25829440}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269\|PubMed:21935722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681861	0.0	LN681861.1 Cucumis melo genomic scaffold, anchoredscaffold00029.
GenBank	LN713261	0.0	LN713261.1 Cucumis melo genomic chromosome, chr_7.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008452730.1	0.0	PREDICTED: protein indeterminate-domain 7-like
Refseq	XP_008452731.1	0.0	PREDICTED: protein indeterminate-domain 7-like
Refseq	XP_016901351.1	0.0	PREDICTED: protein indeterminate-domain 7-like
Swissprot	Q9ZWA6	1e-111	IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBL	A0A1S3BVB6	0.0	A0A1S3BVB6_CUCME; protein indeterminate-domain 7-like
STRING	XP_008452730.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.1	1e-106	C2H2 family protein

Publications ? help Back to Top
Muñoz-Strale D,León G Identification of two highly specific pollen promoters using transcriptomic data. Plant Physiol. Biochem., 2014. 83: p. 292-9 [PMID:25208507] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]