PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MELO3C019813P1

Organism

Cucumis melo

Taxonomic ID

3656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 1371aa MW: 152945 Da PI: 6.5654

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C019813P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.7	0.00082	1256	1280	2	23
EET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 2 kCp..dCgksFsrksnLkrHirt.H 23 kC C +sF++k +L+ H r+ + MELO3C019813P1 1256 KCDleGCRMSFKTKAELTLHKRNqC 1280 78899****************9876 PP
2	zf-C2H2	10.6	0.0018	1279	1302	2	23
EET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCp..dCgksFsrksnLkrHirtH 23 +Cp Cgk+Fs++ + + H+r+H MELO3C019813P1 1279 QCPheGCGKRFSSHKYAMFHQRVH 1302 69999*****************99 PP
3	zf-C2H2	11.4	0.001	1338	1364	1	23
EEET..TTTEEESSHHHHHHHHHH..T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt..H 23 ykC+ Cg sF+ s++ rH r+ H MELO3C019813P1 1338 YKCKieGCGLSFRFVSDYSRHRRKtgH 1364 99*********************9777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00545	3.5E-13	15	55	IPR003349	JmjN domain
PROSITE profile	PS51183	13.661	16	57	IPR003349	JmjN domain
Pfam	PF02375	1.3E-14	17	50	IPR003349	JmjN domain
SuperFamily	SSF51197	1.98E-27	141	354	No hit	No description
SMART	SM00558	5.6E-46	187	356	IPR003347	JmjC domain
PROSITE profile	PS51184	34.989	190	356	IPR003347	JmjC domain
Pfam	PF02373	2.0E-35	220	339	IPR003347	JmjC domain
SMART	SM00355	27	1255	1277	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	9.96E-6	1277	1315	No hit	No description
PROSITE profile	PS50157	12.009	1278	1307	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.51	1278	1302	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.6E-4	1279	1306	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	1280	1302	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	5.9E-10	1307	1332	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.946	1308	1337	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0016	1308	1332	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	1310	1332	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.79E-10	1318	1360	No hit	No description
Gene3D	G3DSA:3.30.160.60	5.1E-11	1333	1361	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.949	1338	1369	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.27	1338	1364	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	1340	1364	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009741	Biological Process	response to brassinosteroid
GO:0009826	Biological Process	unidimensional cell growth
GO:0033169	Biological Process	histone H3-K9 demethylation
GO:0048577	Biological Process	negative regulation of short-day photoperiodism, flowering
GO:0048579	Biological Process	negative regulation of long-day photoperiodism, flowering
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 1371 aa Download sequence Send to blast
MGSLEIPKWL KGLPYAPEFR PTDTEFADPI AYISKIEKEA SAFGICKIIP PFPKPSKKYV 60 VSNLNKSLLR STELSRDLNG AKEGDVRAVF TTRHQELGQS VRKTKGVVQN PQFGVHKQVW 120 QSGEIYTLEQ FESKSKVFAR SVLSGIKEPS PLVVESLFWK AASDKPIYVE YANDVPGSAF 180 GEPEGWRLSN SPWNLQVIAR SPGSLTRYMP DDIPGVTSPM VYIGMLFSWF AWHVEDHELH 240 SMNFLHVGSP KTWYSIPGDQ AFAFEEVVRT QAYGGSVDHL AALTLLGEKT TLLSPEIVIA 300 SGIPCCRLIQ NPGEFVVTFP RAYHVGFSHG FNCGEAANFG TPQWLSVAKD AAVRRAAMNY 360 LPMLSHQQLL YLLTMSFVSR VPRSLLPGVR SSRLRDRQKE ERELMVKKGF VEDILRENNM 420 LSVLLEKESS CRAVLWNPDM LSYSSNSQVA NTNSAVATSP RENVSCNHVE SLDNKVKNMQ 480 NFIDEMTLDL ETMNDIYLES DDLSCDFQVD SGTLACVACG ILGFPFMSVV QPSEKASKEL 540 YVDHLAIHKR GGDFGSKDAH CSSVPDVTCL SENLSVASVP KFENGWNAFS KFLRPRSFCL 600 QHAVDIVELL QKKGGANILV ICHSDYHKIK ANAVAIAEEI GNNFVYNDVR LDIASEEDLR 660 LIDLAVDEDR DECREDWTSR LGINLRHCIK VRKSSPTKQV QHALALGGLF LTRDQGFNLS 720 ALNWLSKRSR SKKMNHLQHR KPFQSMPLKD EVGREKSDCR IVKSEEKFFR YYRRNKKLGG 780 STGVGSVTQP ASSGDSSDLC NVRSVRSNTA ESVIPDSSGT SSQQDVVLQD KSEPNKKTVL 840 PSDTNNGPLV NAIDISSDMH QEQEIIESCN KTNQERDITS EGQSHAGADV CLDEVNLAES 900 SGLHSSNHPE SSKAMCNEDI KSSCGEACDD MAEDGNVGEE IEIANRIKDK EEDSCISIPI 960 KLQHCSAIPI HSQFSHLDDR TEREMNSTSR SNGSEPILTN TGTPDVATSN SRDRTPEVSK 1020 VVCEATNLCN AVTSNEAEVE ILSVSGVDVQ LKAHHSSCLA DEKSIKYLGS QEDRDGFSDT 1080 LIPSTRVEDT PTEPRSPMNE PVSNTCILGE SCPMDVEASG EACDRENLTG EKTSDDDIEC 1140 ADMSINRHIE NLPIQSETGD STEICSSKHK SRLDVVKKRK RKREEELLIE NEFSSFDFIR 1200 SPCEGLRPRV VKNLTNRSGT DVNVAVQEKP ERNRVKKRSD SVTPKPKKET KKGSCKCDLE 1260 GCRMSFKTKA ELTLHKRNQC PHEGCGKRFS SHKYAMFHQR VHDDDRPLKC PWKGCSMSFK 1320 WAWARTEHIR VHTGERPYKC KIEGCGLSFR FVSDYSRHRR KTGHYVDQPA *

Sequence ? help Back to Top

Protein Sequence Length: 1371 aa Download sequence Send to blast

MGSLEIPKWL KGLPYAPEFR PTDTEFADPI AYISKIEKEA SAFGICKIIP PFPKPSKKYV  60
VSNLNKSLLR STELSRDLNG AKEGDVRAVF TTRHQELGQS VRKTKGVVQN PQFGVHKQVW  120
QSGEIYTLEQ FESKSKVFAR SVLSGIKEPS PLVVESLFWK AASDKPIYVE YANDVPGSAF  180
GEPEGWRLSN SPWNLQVIAR SPGSLTRYMP DDIPGVTSPM VYIGMLFSWF AWHVEDHELH  240
SMNFLHVGSP KTWYSIPGDQ AFAFEEVVRT QAYGGSVDHL AALTLLGEKT TLLSPEIVIA  300
SGIPCCRLIQ NPGEFVVTFP RAYHVGFSHG FNCGEAANFG TPQWLSVAKD AAVRRAAMNY  360
LPMLSHQQLL YLLTMSFVSR VPRSLLPGVR SSRLRDRQKE ERELMVKKGF VEDILRENNM  420
LSVLLEKESS CRAVLWNPDM LSYSSNSQVA NTNSAVATSP RENVSCNHVE SLDNKVKNMQ  480
NFIDEMTLDL ETMNDIYLES DDLSCDFQVD SGTLACVACG ILGFPFMSVV QPSEKASKEL  540
YVDHLAIHKR GGDFGSKDAH CSSVPDVTCL SENLSVASVP KFENGWNAFS KFLRPRSFCL  600
QHAVDIVELL QKKGGANILV ICHSDYHKIK ANAVAIAEEI GNNFVYNDVR LDIASEEDLR  660
LIDLAVDEDR DECREDWTSR LGINLRHCIK VRKSSPTKQV QHALALGGLF LTRDQGFNLS  720
ALNWLSKRSR SKKMNHLQHR KPFQSMPLKD EVGREKSDCR IVKSEEKFFR YYRRNKKLGG  780
STGVGSVTQP ASSGDSSDLC NVRSVRSNTA ESVIPDSSGT SSQQDVVLQD KSEPNKKTVL  840
PSDTNNGPLV NAIDISSDMH QEQEIIESCN KTNQERDITS EGQSHAGADV CLDEVNLAES  900
SGLHSSNHPE SSKAMCNEDI KSSCGEACDD MAEDGNVGEE IEIANRIKDK EEDSCISIPI  960
KLQHCSAIPI HSQFSHLDDR TEREMNSTSR SNGSEPILTN TGTPDVATSN SRDRTPEVSK  1020
VVCEATNLCN AVTSNEAEVE ILSVSGVDVQ LKAHHSSCLA DEKSIKYLGS QEDRDGFSDT  1080
LIPSTRVEDT PTEPRSPMNE PVSNTCILGE SCPMDVEASG EACDRENLTG EKTSDDDIEC  1140
ADMSINRHIE NLPIQSETGD STEICSSKHK SRLDVVKKRK RKREEELLIE NEFSSFDFIR  1200
SPCEGLRPRV VKNLTNRSGT DVNVAVQEKP ERNRVKKRSD SVTPKPKKET KKGSCKCDLE  1260
GCRMSFKTKA ELTLHKRNQC PHEGCGKRFS SHKYAMFHQR VHDDDRPLKC PWKGCSMSFK  1320
WAWARTEHIR VHTGERPYKC KIEGCGLSFR FVSDYSRHRR KTGHYVDQPA *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6ip0_A	4e-80	8	370	7	346	Transcription factor jumonji (Jmj) family protein
6ip4_A	4e-80	8	370	7	346	Arabidopsis JMJ13
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	1176	1181	KKRKRK
2	1176	1182	KKRKRKR

Functional Description ? help Back to Top
Source	Description
UniProt	Acts probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269\|PubMed:15377760, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19946624}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681821	0.0	LN681821.1 Cucumis melo genomic scaffold, anchoredscaffold00040.
GenBank	LN713257	0.0	LN713257.1 Cucumis melo genomic chromosome, chr_3.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008456505.1	0.0	PREDICTED: probable lysine-specific demethylase ELF6
Swissprot	Q6BDA0	0.0	ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBL	A0A1S3C4P0	0.0	A0A1S3C4P0_CUCME; probable lysine-specific demethylase ELF6
STRING	XP_008456504.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8031	30	34

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G04240.1	0.0	C2H2 family protein

Publications ? help Back to Top
Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A. PLoS ONE, 2013. 8(7): p. e67987 [PMID:23976921] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Crevillén P, et al. Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state. Nature, 2014. 515(7528): p. 587-90 [PMID:25219852] Yang H,Howard M,Dean C Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74 [PMID:27482092]