PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MELO3C019813P2

Organism

Cucumis melo

Taxonomic ID

3656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 1192aa MW: 132933 Da PI: 6.3634

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C019813P2	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.8	0.00072	1077	1101	2	23
EET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 2 kCp..dCgksFsrksnLkrHirt.H 23 kC C +sF++k +L+ H r+ + MELO3C019813P2 1077 KCDleGCRMSFKTKAELTLHKRNqC 1101 78899****************9876 PP
2	zf-C2H2	10.8	0.0015	1100	1123	2	23
EET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCp..dCgksFsrksnLkrHirtH 23 +Cp Cgk+Fs++ + + H+r+H MELO3C019813P2 1100 QCPheGCGKRFSSHKYAMFHQRVH 1123 69999*****************99 PP
3	zf-C2H2	11.6	0.00086	1159	1185	1	23
EEET..TTTEEESSHHHHHHHHHH..T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt..H 23 ykC+ Cg sF+ s++ rH r+ H MELO3C019813P2 1159 YKCKieGCGLSFRFVSDYSRHRRKtgH 1185 99*********************9777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00558	5.6E-46	8	177	IPR003347	JmjC domain
PROSITE profile	PS51184	34.989	11	177	IPR003347	JmjC domain
SuperFamily	SSF51197	2.31E-26	11	175	No hit	No description
Pfam	PF02373	1.6E-35	41	160	IPR003347	JmjC domain
SMART	SM00355	27	1076	1098	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	8.09E-6	1098	1136	No hit	No description
SMART	SM00355	0.51	1099	1123	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	12.009	1099	1128	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	2.2E-4	1100	1127	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	1101	1123	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	5.0E-10	1128	1153	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.0016	1129	1153	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	11.946	1129	1158	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	1131	1153	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.34E-10	1139	1181	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.4E-11	1154	1182	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.27	1159	1185	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	1159	1190	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	1161	1185	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009741	Biological Process	response to brassinosteroid
GO:0009826	Biological Process	unidimensional cell growth
GO:0033169	Biological Process	histone H3-K9 demethylation
GO:0048577	Biological Process	negative regulation of short-day photoperiodism, flowering
GO:0048579	Biological Process	negative regulation of long-day photoperiodism, flowering
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 1192 aa Download sequence Send to blast
MEGTAGWRLS NSPWNLQVIA RSPGSLTRYM PDDIPGVTSP MVYIGMLFSW FAWHVEDHEL 60 HSMNFLHVGS PKTWYSIPGD QAFAFEEVVR TQAYGGSVDH LAALTLLGEK TTLLSPEIVI 120 ASGIPCCRLI QNPGEFVVTF PRAYHVGFSH GFNCGEAANF GTPQWLSVAK DAAVRRAAMN 180 YLPMLSHQQL LYLLTMSFVS RVPRSLLPGV RSSRLRDRQK EERELMVKKG FVEDILRENN 240 MLSVLLEKES SCRAVLWNPD MLSYSSNSQV ANTNSAVATS PRENVSCNHV ESLDNKVKNM 300 QNFIDEMTLD LETMNDIYLE SDDLSCDFQV DSGTLACVAC GILGFPFMSV VQPSEKASKE 360 LYVDHLAIHK RGGDFGSKDA HCSSVPDVTC LSENLSVASV PKFENGWNAF SKFLRPRSFC 420 LQHAVDIVEL LQKKGGANIL VICHSDYHKI KANAVAIAEE IGNNFVYNDV RLDIASEEDL 480 RLIDLAVDED RDECREDWTS RLGINLRHCI KVRKSSPTKQ VQHALALGGL FLTRDQGFNL 540 SALNWLSKRS RSKKMNHLQH RKPFQSMPLK DEVGREKSDC RIVKSEEKFF RYYRRNKKLG 600 GSTGVGSVTQ PASSGDSSDL CNVRSVRSNT AESVIPDSSG TSSQQDVVLQ DKSEPNKKTV 660 LPSDTNNGPL VNAIDISSDM HQEQEIIESC NKTNQERDIT SEGQSHAGAD VCLDEVNLAE 720 SSGLHSSNHP ESSKAMCNED IKSSCGEACD DMAEDGNVGE EIEIANRIKD KEEDSCISIP 780 IKLQHCSAIP IHSQFSHLDD RTEREMNSTS RSNGSEPILT NTGTPDVATS NSRDRTPEVS 840 KVVCEATNLC NAVTSNEAEV EILSVSGVDV QLKAHHSSCL ADEKSIKYLG SQEDRDGFSD 900 TLIPSTRVED TPTEPRSPMN EPVSNTCILG ESCPMDVEAS GEACDRENLT GEKTSDDDIE 960 CADMSINRHI ENLPIQSETG DSTEICSSKH KSRLDVVKKR KRKREEELLI ENEFSSFDFI 1020 RSPCEGLRPR VVKNLTNRSG TDVNVAVQEK PERNRVKKRS DSVTPKPKKE TKKGSCKCDL 1080 EGCRMSFKTK AELTLHKRNQ CPHEGCGKRF SSHKYAMFHQ RVHDDDRPLK CPWKGCSMSF 1140 KWAWARTEHI RVHTGERPYK CKIEGCGLSF RFVSDYSRHR RKTGHYVDQP A*

Sequence ? help Back to Top

Protein Sequence Length: 1192 aa Download sequence Send to blast

MEGTAGWRLS NSPWNLQVIA RSPGSLTRYM PDDIPGVTSP MVYIGMLFSW FAWHVEDHEL  60
HSMNFLHVGS PKTWYSIPGD QAFAFEEVVR TQAYGGSVDH LAALTLLGEK TTLLSPEIVI  120
ASGIPCCRLI QNPGEFVVTF PRAYHVGFSH GFNCGEAANF GTPQWLSVAK DAAVRRAAMN  180
YLPMLSHQQL LYLLTMSFVS RVPRSLLPGV RSSRLRDRQK EERELMVKKG FVEDILRENN  240
MLSVLLEKES SCRAVLWNPD MLSYSSNSQV ANTNSAVATS PRENVSCNHV ESLDNKVKNM  300
QNFIDEMTLD LETMNDIYLE SDDLSCDFQV DSGTLACVAC GILGFPFMSV VQPSEKASKE  360
LYVDHLAIHK RGGDFGSKDA HCSSVPDVTC LSENLSVASV PKFENGWNAF SKFLRPRSFC  420
LQHAVDIVEL LQKKGGANIL VICHSDYHKI KANAVAIAEE IGNNFVYNDV RLDIASEEDL  480
RLIDLAVDED RDECREDWTS RLGINLRHCI KVRKSSPTKQ VQHALALGGL FLTRDQGFNL  540
SALNWLSKRS RSKKMNHLQH RKPFQSMPLK DEVGREKSDC RIVKSEEKFF RYYRRNKKLG  600
GSTGVGSVTQ PASSGDSSDL CNVRSVRSNT AESVIPDSSG TSSQQDVVLQ DKSEPNKKTV  660
LPSDTNNGPL VNAIDISSDM HQEQEIIESC NKTNQERDIT SEGQSHAGAD VCLDEVNLAE  720
SSGLHSSNHP ESSKAMCNED IKSSCGEACD DMAEDGNVGE EIEIANRIKD KEEDSCISIP  780
IKLQHCSAIP IHSQFSHLDD RTEREMNSTS RSNGSEPILT NTGTPDVATS NSRDRTPEVS  840
KVVCEATNLC NAVTSNEAEV EILSVSGVDV QLKAHHSSCL ADEKSIKYLG SQEDRDGFSD  900
TLIPSTRVED TPTEPRSPMN EPVSNTCILG ESCPMDVEAS GEACDRENLT GEKTSDDDIE  960
CADMSINRHI ENLPIQSETG DSTEICSSKH KSRLDVVKKR KRKREEELLI ENEFSSFDFI  1020
RSPCEGLRPR VVKNLTNRSG TDVNVAVQEK PERNRVKKRS DSVTPKPKKE TKKGSCKCDL  1080
EGCRMSFKTK AELTLHKRNQ CPHEGCGKRF SSHKYAMFHQ RVHDDDRPLK CPWKGCSMSF  1140
KWAWARTEHI RVHTGERPYK CKIEGCGLSF RFVSDYSRHR RKTGHYVDQP A*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6ip0_A	6e-55	9	191	160	346	Transcription factor jumonji (Jmj) family protein
6ip4_A	6e-55	9	191	160	346	Arabidopsis JMJ13
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	997	1002	KKRKRK
2	997	1003	KKRKRKR

Functional Description ? help Back to Top
Source	Description
UniProt	Acts probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269\|PubMed:15377760, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19946624}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681821	0.0	LN681821.1 Cucumis melo genomic scaffold, anchoredscaffold00040.
GenBank	LN713257	0.0	LN713257.1 Cucumis melo genomic chromosome, chr_3.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008456505.1	0.0	PREDICTED: probable lysine-specific demethylase ELF6
Swissprot	Q6BDA0	0.0	ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBL	A0A1S3C4P0	0.0	A0A1S3C4P0_CUCME; probable lysine-specific demethylase ELF6
STRING	XP_008456504.1	0.0	(Cucumis melo)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G04240.1	0.0	C2H2 family protein

Publications ? help Back to Top
Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A. PLoS ONE, 2013. 8(7): p. e67987 [PMID:23976921] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Crevillén P, et al. Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state. Nature, 2014. 515(7528): p. 587-90 [PMID:25219852] Yang H,Howard M,Dean C Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74 [PMID:27482092]