PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C022282P1
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family MYB
Protein Properties Length: 167aa    MW: 19323.3 Da    PI: 10.7346
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C022282P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding409e-131459146
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                     +g+W  eEde l++ v+++G+++W++I ++  + Rt+k+c++rw +
   MELO3C022282P1 14 KGPWKLEEDEVLLNHVNRFGPRDWSSIRSKGLLQRTGKSCRLRWVN 59
                     79*************************8887799**********87 PP
2Myb_DNA-binding48.81.6e-1570109344
                      SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS
  Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 
                      ++T+eE++  +++ +q+G++ W++Ia +++ gRt++++k++w
   MELO3C022282P1  70 KFTAEEEKMVIELQAQFGNK-WAKIATYLP-GRTDNDVKNFW 109
                      79******************.*********.*********** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129413.463961IPR017930Myb domain
Gene3DG3DSA:1.10.10.604.9E-201062IPR009057Homeodomain-like
SMARTSM007174.5E-91363IPR001005SANT/Myb domain
SuperFamilySSF466891.73E-2813109IPR009057Homeodomain-like
PfamPF002496.7E-111459IPR001005SANT/Myb domain
CDDcd001675.64E-91661No hitNo description
PROSITE profilePS5129420.08862117IPR017930Myb domain
Gene3DG3DSA:1.10.10.601.2E-1963115IPR009057Homeodomain-like
SMARTSM007171.2E-1367115IPR001005SANT/Myb domain
PfamPF002495.9E-1470109IPR001005SANT/Myb domain
CDDcd001677.49E-1170109No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0048235Biological Processpollen sperm cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 167 aa     Download sequence    Send to blast
MEDRRSQSHE VLRKGPWKLE EDEVLLNHVN RFGPRDWSSI RSKGLLQRTG KSCRLRWVNK  60
LRPNLKNGCK FTAEEEKMVI ELQAQFGNKW AKIATYLPGR TDNDVKNFWS SRQKRLARLL  120
QTSPAPSKLQ RSAKKETPVD FDIPTMEVFS LLISSDILDL RFLAVL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C1e-281211525126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6819251e-167LN681925.1 Cucumis melo genomic scaffold, anchoredscaffold00052.
GenBankLN7132651e-167LN713265.1 Cucumis melo genomic chromosome, chr_11.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008459792.11e-104PREDICTED: myb-related protein 308-like
SwissprotA0A178VEK74e-69DUO1_ARATH; Transcription factor DUO1
TrEMBLA0A1S3CB011e-103A0A1S3CB01_CUCME; myb-related protein 308-like
STRINGXP_008459792.11e-104(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36933164
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.13e-71MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]