PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MELO3C027075P1

Organism

Cucumis melo

Taxonomic ID

3656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 186aa MW: 21129.2 Da PI: 10.0568

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C027075P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	19	3.9e-06	74	96	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H MELO3C027075P1 74 FVCEICNKGFQRDQNLQLHRRGH 96 89*******************88 PP
2	zf-C2H2	14.9	7.7e-05	150	172	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k++ +s+ k H +t+ MELO3C027075P1 150 WKCDKCSKVYAVQSDWKAHSKTC 172 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	4.5E-6	73	96	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.96E-7	73	96	No hit	No description
Pfam	PF12171	2.2E-5	74	96	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.949	74	96	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	74	96	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	76	96	IPR007087	Zinc finger, C2H2
SMART	SM00355	280	115	145	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	4.6E-5	138	171	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.96E-7	145	170	No hit	No description
SMART	SM00355	130	150	170	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 186 aa Download sequence Send to blast
MSNSTSLSEE AASVSSTTRI HPDFTSLNPL LPSFSDIHHP PQKPKKKRSL PGNPDPDAEV 60 IALSPKTLLA TNRFVCEICN KGFQRDQNLQ LHRRGHNLPW KLKQRNNKEV KKKAYVCPEP 120 SCVHHHPSRA LGDLTGIKKH YCRKHGEKKW KCDKCSKVYA VQSDWKAHSK TCGTREYRCD 180 CGTLFS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	4e-21	146	186	3	43	Zinc finger protein JACKDAW
5b3h_F	4e-21	146	186	3	43	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000305}.
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681965	0.0	LN681965.1 Cucumis melo genomic scaffold, unanchored_scaffold00252.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008465513.1	1e-138	PREDICTED: protein indeterminate-domain 12-like
Refseq	XP_011659290.1	1e-136	PREDICTED: protein indeterminate-domain 9
Swissprot	O22759	1e-96	IDD12_ARATH; Protein indeterminate-domain 12
Swissprot	Q9SCQ6	3e-96	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A0A0K7A5	1e-135	A0A0A0K7A5_CUCSA; Uncharacterized protein
TrEMBL	A0A1S3CP21	1e-136	A0A1S3CP21_CUCME; protein indeterminate-domain 12-like
STRING	XP_008465513.1	1e-137	(Cucumis melo)
STRING	XP_004146996.1	1e-136	(Cucumis sativus)
STRING	XP_004171470.1	1e-136	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G02670.1	6e-99	indeterminate(ID)-domain 12

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]