PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MLOC_14619.1
Organism
Hordeum vulgare
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
Family EIL
Protein Properties Length: 651aa    MW: 71782.4 Da    PI: 4.8622
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MLOC_14619.1genomeIBSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3506.61.2e-154814691354
                   XXXXXXXXXXXXXXXXXXXXXXX..XXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
          EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaa....tgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasdsLra 93 
                   eel++rmw+d+m+lkrlke ++++ +++ a      +  k ++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv+gasd+Lra
  MLOC_14619.1  81 EELERRMWRDRMKLKRLKELQQSRGKEQAAGgggvGDGLKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPVSGASDNLRA 177
                   8*********************9875555558888788899******************************************************** PP

                   XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHHHHHT--TT- CS
          EIN3  94 WWkekvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelwwgelglskdq 190
                   WWkekv+fdrngpaai+kyqa+n+++++es+l + +++++hsl+elqDTtlgSLLsalmqhcdppqrrfplekg++pPWWP+G+e+ww+elg++kdq
  MLOC_14619.1 178 WWKEKVRFDRNGPAAIAKYQADNAVPGSESELAS-GTASPHSLQELQDTTLGSLLSALMQHCDPPQRRFPLEKGISPPWWPSGDEEWWPELGIPKDQ 273
                   ********************************66.************************************************************** PP

                   -.-----GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXXXX....XXXX....XXXXXXXXXX CS
          EIN3 191 gtppykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsahss....slrk....qspkvtlsce 279
                   g+ppykkphdlkkawkvsvLtavikhmsp+ie+ir+l+rqsk+lqdkm+ake  ++l+v++qee+++ ++++  +            ++ ++++s+ 
  MLOC_14619.1 274 GPPPYKKPHDLKKAWKVSVLTAVIKHMSPDIEKIRRLVRQSKCLQDKMTAKEISTWLAVVKQEEELFMRLHPGARppatA--AggiaSAISFNASS- 367
                   ************************************************************************94434441..23332555555555. PP

                   XXXXXXXXXXXX.XXXXXXXXXX............................XXXXXXXXXXXXXXXXXXXXX......XXXXXXX.XXXXXXXXXXX CS
          EIN3 280 qkedvegkkeskikhvqavktta............................gfpvvrkrkkkpsesakvsskevsrtcqssqfrgsetelifadkns 348
                   +++dv++ ++ k  ++ ++k ++                            +++ v+kr +  +e++ + +++v + c++ q+++s++  +f d+n+
  MLOC_14619.1 368 SEYDVDVADDCKGDEAGTHKMAMadptafnlgaailndkflmqapmkeetaDMEYVQKRSAVAAEPELMLNNRV-YICNNVQCPHSDYGYGFLDRNA 463
                   599***7777777777766666578888******************************************9976.********************** PP

                   XXXXXX CS
          EIN3 349 isqney 354
                   +++++y
  MLOC_14619.1 464 RNSHQY 469
                   ****98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048731.0E-13181337No hitNo description
Gene3DG3DSA:1.10.3180.105.9E-74211345IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167681.23E-60216341IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0009873Biological Processethylene-activated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 651 aa     Download sequence    Send to blast
MMGGGGGLLM DQGMAFPGVH NFVDLLQQNG NDKNLGFGSL MPQTSSGDQC VMGEGDLVDP  60
PTDNFPDAGE DDSDDDVDDI EELERRMWRD RMKLKRLKEL QQSRGKEQAA GGGGVGDGLK  120
PRQSQEQARR KKMSRAQDGI LKYMLKMMEV CRAQGFVYGI IPEKGKPVSG ASDNLRAWWK  180
EKVRFDRNGP AAIAKYQADN AVPGSESELA SGTASPHSLQ ELQDTTLGSL LSALMQHCDP  240
PQRRFPLEKG ISPPWWPSGD EEWWPELGIP KDQGPPPYKK PHDLKKAWKV SVLTAVIKHM  300
SPDIEKIRRL VRQSKCLQDK MTAKEISTWL AVVKQEEELF MRLHPGARPP ATAAGGIASA  360
ISFNASSSEY DVDVADDCKG DEAGTHKMAM ADPTAFNLGA AILNDKFLMQ APMKEETADM  420
EYVQKRSAVA AEPELMLNNR VYICNNVQCP HSDYGYGFLD RNARNSHQYT CKYNDALPPS  480
AENKAAPPAP PQVFPAAAYN QQNHGLNNLD FGLPMDGQRS IAELMNMYDT AFPANKNMGN  540
DDVTIIERPN SLTPGTQMDE GFFGQGNGIG GNGDSMFSDV SNMMQQQQQQ QPQQQQQAPA  600
QQQFFIRDET PQFGNQMGGI SGASDFRFGS GFNMSGAVDY PQKNDGPNWY Y
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A6e-742143451132Protein ETHYLENE INSENSITIVE 3
4zds_B6e-742143451132Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as a positive regulator in the ethylene response pathway (PubMed:16786297, PubMed:28829777, PubMed:27701783, PubMed:25995326). Required for the inhibition of root growth by ethylene in etiolated seedlings (PubMed:25995326, PubMed:28829777). Functions upstream of the auxin biosynthetic gene YUCCA8 and directly activates its expression (PubMed:28829777). Functions downstream of the ethylene signaling factor EIN2 in disease resistance against the rice blast fungus (Magnaporthe oryzae) (PubMed:27701783). Binds directly to the promoters of the NADPH oxidases RBOHA and RBOHB, and the jasmonate biosynthetic gene OPR4 to activate their expression during fungal infection (PubMed:27701783). May enhance disease resistance by facilitating reactive oxygen species (ROS) generation and jasmonate biosynthesis with subsequent phytoalexin accumulation during Magnaporthe oryzae infection (PubMed:27701783). Acts as negative regulator of salt tolerance (PubMed:25995326). During salt stress, activates the cation transporter HKT1, which mediates increased sodium uptake in roots, and contributes to sodium accumulation and salt toxicity (PubMed:25995326). Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253). Possesses transactivation activity in protoplasts (PubMed:25995326). {ECO:0000269|PubMed:16786297, ECO:0000269|PubMed:25995326, ECO:0000269|PubMed:27701783, ECO:0000269|PubMed:28829777, ECO:0000269|PubMed:30002253}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00367DAPTransfer from AT3G20770Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMLOC_14619.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the fungal pathogen Magnaporthe oryzae. {ECO:0000269|PubMed:27701783}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2483110.0AK248311.1 Hordeum vulgare subsp. vulgare cDNA clone: FLbaf51m23, mRNA sequence.
GenBankAK3638910.0AK363891.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2019M20.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020198090.10.0ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotQ10M410.0EIL1A_ORYSJ; Protein ETHYLENE-INSENSITIVE 3-like 1a
TrEMBLF2DJ230.0F2DJ23_HORVV; Predicted protein
STRINGMLOC_14619.10.0(Hordeum vulgare)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP63838168
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27050.11e-158ETHYLENE-INSENSITIVE3-like 1
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  3. Yang C, et al.
    Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice.
    Plant J., 2017. 89(2): p. 338-353
    [PMID:27701783]
  4. Qin H, et al.
    The activation of OsEIL1 on YUC8 transcription and auxin biosynthesis is required for ethylene-inhibited root elongation in rice early seedling development.
    PLoS Genet., 2017. 13(8): p. e1006955
    [PMID:28829777]
  5. Kuroha T, et al.
    Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding.
    Science, 2018. 361(6398): p. 181-186
    [PMID:30002253]