PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MLOC_14619.2
Organism
Hordeum vulgare
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
Family EIL
Protein Properties Length: 487aa    MW: 53579.5 Da    PI: 4.4724
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MLOC_14619.2genomeIBSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3184.59.8e-57811961112
                   XXXXXXXXXXXXXXXXXXXXXXX..XXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
          EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaa....tgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasdsLra 93 
                   eel++rmw+d+m+lkrlke ++++ +++ a      +  k ++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv+gasd+Lra
  MLOC_14619.2  81 EELERRMWRDRMKLKRLKELQQSRGKEQAAGgggvGDGLKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPVSGASDNLRA 177
                   8*********************9875555558888788899******************************************************** PP

                   XXXXXXXXXXXXXXXXXXX CS
          EIN3  94 WWkekvefdrngpaaisky 112
                   WWkekv+fdrngpaai++ 
  MLOC_14619.2 178 WWKEKVRFDRNGPAAIANA 196
                   *****************96 PP
2EIN329.31.5e-09203305279354
                   XXXXXXXXXXXXX.XXXXXXXXXX............................XXXXXXXXXXXXXXXXXXXXX......XXXXXXX.XXXXXXXXXX CS
          EIN3 279 eqkedvegkkeskikhvqavktta............................gfpvvrkrkkkpsesakvsskevsrtcqssqfrgsetelifadkn 347
                   ++++dv++ ++ k  ++ ++k ++                            +++ v+kr +  +e++ + +++v + c++ q+++s++  +f d+n
  MLOC_14619.2 203 SSEYDVDVADDCKGDEAGTHKMAMadptafnlgaailndkflmqapmkeetaDMEYVQKRSAVAAEPELMLNNRV-YICNNVQCPHSDYGYGFLDRN 298
                   5578888666666555555555446666788888888888888888888888*******************9976.********************* PP

                   XXXXXXX CS
          EIN3 348 sisqney 354
                   ++++++y
  MLOC_14619.2 299 ARNSHQY 305
                   *****98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048739.3E-5481198No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0009873Biological Processethylene-activated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 487 aa     Download sequence    Send to blast
MMGGGGGLLM DQGMAFPGVH NFVDLLQQNG NDKNLGFGSL MPQTSSGDQC VMGEGDLVDP  60
PTDNFPDAGE DDSDDDVDDI EELERRMWRD RMKLKRLKEL QQSRGKEQAA GGGGVGDGLK  120
PRQSQEQARR KKMSRAQDGI LKYMLKMMEV CRAQGFVYGI IPEKGKPVSG ASDNLRAWWK  180
EKVRFDRNGP AAIANAISFN ASSSEYDVDV ADDCKGDEAG THKMAMADPT AFNLGAAILN  240
DKFLMQAPMK EETADMEYVQ KRSAVAAEPE LMLNNRVYIC NNVQCPHSDY GYGFLDRNAR  300
NSHQYTCKYN DALPPSAENK AAPPAPPQVF PAAAYNQQNH GLNNLDFGLP MDGQRSIAEL  360
MNMYDTAFPA NKNMGNDDVT IIERPNSLTP GTQMDEGFFG QGNGIGGNGD SMFSDVSNMM  420
QQQQQQQPQQ QQQAPAQQQF FIRDETPQFG NQMGGISGAS DFRFGSGFNM SGAVDYPQKN  480
DGPNWYY
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as a positive regulator in the ethylene response pathway (PubMed:16786297, PubMed:28829777, PubMed:27701783, PubMed:25995326). Required for the inhibition of root growth by ethylene in etiolated seedlings (PubMed:25995326, PubMed:28829777). Functions upstream of the auxin biosynthetic gene YUCCA8 and directly activates its expression (PubMed:28829777). Functions downstream of the ethylene signaling factor EIN2 in disease resistance against the rice blast fungus (Magnaporthe oryzae) (PubMed:27701783). Binds directly to the promoters of the NADPH oxidases RBOHA and RBOHB, and the jasmonate biosynthetic gene OPR4 to activate their expression during fungal infection (PubMed:27701783). May enhance disease resistance by facilitating reactive oxygen species (ROS) generation and jasmonate biosynthesis with subsequent phytoalexin accumulation during Magnaporthe oryzae infection (PubMed:27701783). Acts as negative regulator of salt tolerance (PubMed:25995326). During salt stress, activates the cation transporter HKT1, which mediates increased sodium uptake in roots, and contributes to sodium accumulation and salt toxicity (PubMed:25995326). Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253). Possesses transactivation activity in protoplasts (PubMed:25995326). {ECO:0000269|PubMed:16786297, ECO:0000269|PubMed:25995326, ECO:0000269|PubMed:27701783, ECO:0000269|PubMed:28829777, ECO:0000269|PubMed:30002253}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00367DAPTransfer from AT3G20770Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMLOC_14619.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the fungal pathogen Magnaporthe oryzae. {ECO:0000269|PubMed:27701783}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2483110.0AK248311.1 Hordeum vulgare subsp. vulgare cDNA clone: FLbaf51m23, mRNA sequence.
GenBankAK3638910.0AK363891.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2019M20.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020198090.11e-170ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotQ10M411e-126EIL1A_ORYSJ; Protein ETHYLENE-INSENSITIVE 3-like 1a
TrEMBLA0A446S4Y80.0A0A446S4Y8_TRITD; Uncharacterized protein
STRINGMLOC_14619.10.0(Hordeum vulgare)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27050.13e-46ETHYLENE-INSENSITIVE3-like 1
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  3. Yang C, et al.
    Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice.
    Plant J., 2017. 89(2): p. 338-353
    [PMID:27701783]
  4. Qin H, et al.
    The activation of OsEIL1 on YUC8 transcription and auxin biosynthesis is required for ethylene-inhibited root elongation in rice early seedling development.
    PLoS Genet., 2017. 13(8): p. e1006955
    [PMID:28829777]
  5. Kuroha T, et al.
    Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding.
    Science, 2018. 361(6398): p. 181-186
    [PMID:30002253]