PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MLOC_66134.4
Organism
Hordeum vulgare
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
Family WRKY
Protein Properties Length: 76aa    MW: 9056.19 Da    PI: 9.6789
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MLOC_66134.4genomeIBSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY64.81.4e-202975144
                  ---SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSS CS
          WRKY  1 ldDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaed 44
                  ldDg++WrKYGqKe+++s+++r+Y+rCt++    C ++++v+r+++d
  MLOC_66134.4 29 LDDGHAWRKYGQKEIHNSKHSRAYFRCTHKydqLCAAQRQVQRCDDD 75
                  59***************************98878**********987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.0E-191575IPR003657WRKY domain
SuperFamilySSF1182903.92E-182375IPR003657WRKY domain
PROSITE profilePS5081116.2492476IPR003657WRKY domain
SMARTSM007744.2E-182976IPR003657WRKY domain
PfamPF031064.9E-173075IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009862Biological Processsystemic acquired resistance, salicylic acid mediated signaling pathway
GO:0009864Biological Processinduced systemic resistance, jasmonic acid mediated signaling pathway
GO:0010200Biological Processresponse to chitin
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0050832Biological Processdefense response to fungus
GO:1900056Biological Processnegative regulation of leaf senescence
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 76 aa     Download sequence    Send to blast
MFAKFAPPFW RCSRTQQSSV VFTKSIKSLD DGHAWRKYGQ KEIHNSKHSR AYFRCTHKYD  60
QLCAAQRQVQ RCDDDE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ir8_A2e-272675554OsWRKY45
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the regulation of osmotic stress responses and stomatal movement (PubMed:24773321). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora (PubMed:22316300). Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2 (PubMed:22325892). Together with WRKY54 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847). {ECO:0000250, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321, ECO:0000269|PubMed:28576847}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00408DAPTransfer from AT3G56400Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMLOC_66134.4
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by drought, salt and hydrogen peroxide treatments (PubMed:24773321). Induced by salicylic acid (SA) (PubMed:22268143, PubMed:22325892). Up-regulated by E.amylovora (PubMed:22316300). Triggered by P.syringae (PubMed:22325892). {ECO:0000269|PubMed:22268143, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEU6654404e-76EU665440.1 Triticum aestivum WRKY11 transcription factor mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020148215.17e-33probable WRKY transcription factor 70
SwissprotQ9SKD93e-18WRK46_ARATH; Probable WRKY transcription factor 46
TrEMBLA0A287X4F83e-50A0A287X4F8_HORVV; Uncharacterized protein
STRINGMLOC_66134.29e-40(Hordeum vulgare)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G46400.11e-20WRKY DNA-binding protein 46
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Sheikh AH, et al.
    Regulation of WRKY46 Transcription Factor Function by Mitogen-Activated Protein Kinases in Arabidopsis thaliana.
    Front Plant Sci, 2016. 7: p. 61
    [PMID:26870073]
  3. Yan JY, et al.
    A WRKY Transcription Factor Regulates Fe Translocation under Fe Deficiency.
    Plant Physiol., 2016. 171(3): p. 2017-27
    [PMID:27208259]
  4. Chen J, et al.
    Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses.
    Plant Cell, 2017. 29(6): p. 1425-1439
    [PMID:28576847]
  5. Ma J, et al.
    Overexpression of TaWRKY146 Increases Drought Tolerance through Inducing Stomatal Closure in Arabidopsis thaliana.
    Front Plant Sci, 2017. 8: p. 2036
    [PMID:29225611]