PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MLOC_76689.2

Organism

Hordeum vulgare

Taxonomic ID

4513

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum

Family

AP2

Protein Properties

Length: 161aa MW: 18182.5 Da PI: 8.0051

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MLOC_76689.2	genome	IBSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	23.3	1.6e-07	8	34	29	55
AP2 29 krfslgkfgtaeeAakaaiaarkkleg 55 ++++lg+++t+++Aa+a++ a++k++g MLOC_76689.2 8 ASVYLGSYDTEQKAARAYDVAALKYWG 34 789*****99***********97 PP
2	AP2	50.7	4.3e-16	77	128	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s y+GV+++ k+grW A+I g ++ ++lg+f t+eeAa+a++ a+ +++g MLOC_76689.2 77 SIYRGVTRRQKDGRWQARIGLiA---G-TRDIYLGTFKTEEEAAEAYDIAAIEIRG 128 57**************88832...2.5***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	12.154	1	42	IPR001471	AP2/ERF domain
SMART	SM00380	3.8E-5	4	48	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.47E-11	5	44	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	5.2E-11	7	42	IPR001471	AP2/ERF domain
Pfam	PF00847	7.8E-5	8	34	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.84E-18	77	138	IPR016177	DNA-binding domain
Pfam	PF00847	3.5E-10	77	128	IPR001471	AP2/ERF domain
CDD	cd00018	1.11E-22	77	136	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.0E-19	78	137	IPR001471	AP2/ERF domain
SMART	SM00380	2.7E-27	78	142	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	18.624	78	136	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-6	79	90	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-6	118	138	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 161 aa Download sequence Send to blast
MVFQYGGASV YLGSYDTEQK AARAYDVAAL KYWGLNTKLN FSISEYEKEL ADIQDMSPEE 60 CVTYLRRRSS CFSRGASIYR GVTRRQKDGR WQARIGLIAG TRDIYLGTFK TEEEAAEAYD 120 IAAIEIRGKN AVTNFDRSNY MDRGMHCIEG AGLKLLATKP E

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	65	86	RRRSSCFSRGASIYRGVTRRQK

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
UniProt	Transcription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269\|PubMed:10528263, ECO:0000269\|PubMed:10639184, ECO:0000269\|PubMed:10948255, ECO:0000269\|PubMed:11041883, ECO:0000269\|PubMed:12183381, ECO:0000269\|PubMed:12271029, ECO:0000269\|PubMed:12655002, ECO:0000269\|PubMed:8742706, ECO:0000269\|PubMed:8742707, ECO:0000269\|PubMed:9001406, ECO:0000269\|PubMed:9093862, ECO:0000269\|PubMed:9118807}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	MLOC_76689.2

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK252982	0.0	AK252982.1 Hordeum vulgare subsp. vulgare cDNA clone: FLbaf180b05, mRNA sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020153211.1	1e-107	AP2-like ethylene-responsive transcription factor BBM1
Refseq	XP_020174447.1	1e-107	AP2-like ethylene-responsive transcription factor BBM1
Swissprot	Q1PFE1	1e-58	AIL1_ARATH; AP2-like ethylene-responsive transcription factor AIL1
Swissprot	Q38914	1e-57	ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBL	A0A446VN99	1e-114	A0A446VN99_TRITD; Uncharacterized protein
STRING	Traes_6BL_340C2A897.1	1e-106	(Triticum aestivum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G72570.1	1e-49	AP2 family protein

Publications ? help Back to Top
Todd J,Post-Beittenmiller D,Jaworski JG KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana. Plant J., 1999. 17(2): p. 119-30 [PMID:10074711] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Horstman A,Willemsen V,Boutilier K,Heidstra R AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks. Trends Plant Sci., 2014. 19(3): p. 146-57 [PMID:24280109] Li C, et al. Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis. PLoS ONE, 2014. 9(4): p. e94830 [PMID:24756087] Wynn AN,Seaman AA,Jones AL,Franks RG Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development. Front Plant Sci, 2014. 5: p. 130 [PMID:24778638] Randall RS, et al. AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins. Biol Open, 2015. 4(10): p. 1229-36 [PMID:26340943] Meng LS,Wang ZB,Yao SQ,Liu A The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis. J. Cell. Sci., 2015. 128(21): p. 3922-32 [PMID:26395398] Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis. Plant Physiol., 2016. 170(1): p. 283-93 [PMID:26537561] Krizek BA, et al. RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways. Plant Physiol., 2016. 171(3): p. 2069-84 [PMID:27208279] Han H,Krizek BA AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels. Plant Mol. Biol., 2016. 92(4-5): p. 597-612 [PMID:27605095] Karpinska B,Alomrani SO,Foyer CH Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018. [PMID:28808105] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]