PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.01G199900.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family bHLH
Protein Properties Length: 504aa    MW: 55617.9 Da    PI: 5.5774
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.01G199900.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.78.8e-13356402455
                          HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                  HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                          +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  Manes.01G199900.1.p 356 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAITYITDLQ 402
                          799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142156.3E-4248229IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.831352401IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000837.07E-14355406No hitNo description
SuperFamilySSF474591.83E-18355421IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.9E-10356402IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.5E-18356420IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003535.4E-14358407IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS516719.048437503IPR002912ACT domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 504 aa     Download sequence    Send to blast
MGEKFLLNEE KAMVESLLGM EACEFLIASA SNNVMADLVS PPSNLGVQQG LCQLVDCSNW  60
NYAILWYASS LKSGGSILSW GDGVCRNPQG GGAGEGRDSK FEAAEKREEV KKIVLQKLHA  120
CFNMSDGDNY AASLDGVSDV ELFYLISMYF TFRCDSSYTP AESYKSGRSI WASDVVSCLE  180
QYQLRSVLAR SAGLQTVVFL PVKCGVVELG SIKSIPEEHN LVERAKTIFG VSNAVQARAC  240
PKIFGHELSL GGTKSRSISI NFSPKVEDDL VFASESYAEA IGTNPVYGST SNGCTGDANE  300
AKLFPHLNQM NLSGFNAETM VTGLEQPKDD LSPQLDERKP RKRGRKPANG REEPLNHVEA  360
ERQRREKLNQ RFYALRAVVP NISKMDKASL LGDAITYITD LQMKIRVLET EKEMTNNRRK  420
QPSVPEIDFQ SRQEDAVVRL SCPLDAHPVS RILETFQEHQ ITAQECNVST TTENDKIIHT  480
FSIRTQSGVA EQLKEKLETA LSK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-28350418270Transcription factor MYC2
5gnj_B2e-28350418270Transcription factor MYC2
5gnj_E2e-28350418270Transcription factor MYC2
5gnj_F2e-28350418270Transcription factor MYC2
5gnj_G2e-28350418270Transcription factor MYC2
5gnj_I2e-28350418270Transcription factor MYC2
5gnj_M2e-28350418270Transcription factor MYC2
5gnj_N2e-28350418270Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1337345RKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00099PBMTransfer from AT4G16430Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.01G199900.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021606989.10.0transcription factor bHLH3
SwissprotA0A3Q7H2160.0MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A2C9WPT10.0A0A2C9WPT1_MANES; Uncharacterized protein
STRINGcassava4.1_006027m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF82633445
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-179bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]