PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.02G049700.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family WRKY
Protein Properties Length: 529aa    MW: 57833.1 Da    PI: 7.1849
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.02G049700.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY106.41.5e-33235291259
                          --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                          dDgynWrKYGqK++kgse+prsYY+Ct+ +Cpvkkkvers+ d++++ei+Y+g Hnhe
  Manes.02G049700.1.p 235 DDGYNWRKYGQKPIKGSEYPRSYYKCTHLNCPVKKKVERSS-DGQITEIIYKGLHNHE 291
                          8****************************************.***************8 PP
2WRKY107.28.4e-34414472159
                          ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                          ldDgy+WrKYGqK+vkg+++prsYY+CtsagC+v+k+ver+a dpk+v++tYeg+Hnh+
  Manes.02G049700.1.p 414 LDDGYRWRKYGQKVVKGNPHPRSYYKCTSAGCNVRKHVERAAADPKAVITTYEGKHNHD 472
                          59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.808.4E-30225293IPR003657WRKY domain
PROSITE profilePS5081124.432229293IPR003657WRKY domain
SuperFamilySSF1182909.15E-27233293IPR003657WRKY domain
SMARTSM007742.0E-38234292IPR003657WRKY domain
PfamPF031067.3E-26235291IPR003657WRKY domain
Gene3DG3DSA:2.20.25.803.2E-37399474IPR003657WRKY domain
SuperFamilySSF1182901.44E-29406474IPR003657WRKY domain
PROSITE profilePS5081138.733409474IPR003657WRKY domain
SMARTSM007744.5E-40414473IPR003657WRKY domain
PfamPF031062.1E-26415472IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 529 aa     Download sequence    Send to blast
MAEKQKSATM TTTPRPTILL PPRPSMDTFF TGGLSPGPMT LVSSFFSDNY PDSDCRSFSQ  60
LLAGAMASPI ARPAFFTDTS VPNGNTSSVK QDGAENNTYL GFKQSRPMNL LVAPSPLFTV  120
PPGLSPSGLL NSPAFFSPPQ SPFGMSHQQA LAQVTAQAAL AAQSHMHMQA QYQPAPVTDS  180
TELLTHHQSF TTGEASQQQM LPSTSELPSS MVESSDLSHS DRKQQQPLAV DKPSDDGYNW  240
RKYGQKPIKG SEYPRSYYKC THLNCPVKKK VERSSDGQIT EIIYKGLHNH EQPPSNKRAK  300
DNNDLNGGTN SQAKPELSSQ VPSGDMNKRE TIPSHSVHGR EQESNQADPI ELPGSSDSEE  360
AGDGTTRADG RDDDDEPNPK RRHTDVGTSE AALPHKTVTE PKIIVQTRSE VDLLDDGYRW  420
RKYGQKVVKG NPHPRSYYKC TSAGCNVRKH VERAAADPKA VITTYEGKHN HDVPAARNSS  480
HNSANNSAPQ LKPQKVVTEK HPLLEGMDFG NSDQRPVLLR LKEEEITV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A3e-40235475878Probable WRKY transcription factor 4
2lex_A3e-40235475878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.02G049700.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKT8275790.0KT827579.1 Manihot esculenta WRKY transcription factor 4 mRNA, complete cds.
GenBankKT8275880.0KT827588.1 Manihot esculenta WRKY transcription factor 13 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021604686.10.0probable WRKY transcription factor 4
SwissprotQ9XI901e-152WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A2C9WAZ10.0A0A2C9WAZ1_MANES; Uncharacterized protein
STRINGcassava4.1_005605m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF154534100
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G13960.11e-122WRKY DNA-binding protein 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Wei Y, et al.
    Genome-Wide Identification and Expression Analysis of the WRKY Gene Family in Cassava.
    Front Plant Sci, 2016. 7: p. 25
    [PMID:26904033]
  4. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]