PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.02G082500.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family ARF
Protein Properties Length: 739aa    MW: 83013.2 Da    PI: 6.2664
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.02G082500.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.91.9e-2344145199
                          EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEE CS
                   B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFk 83 
                          f+k+lt sd++++g +++p++ ae+        +++++  ++l+ +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F 
  Manes.02G082500.1.p  44 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfsQQPPA--QELIARDLHDVEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDSVLFI 131
                          99*****************************8544444..48************************************************ PP

                          E-SSSEE..EEEEE-S CS
                   B3  84 ldgrsefelvvkvfrk 99 
                            ++++ +l+++++r+
  Manes.02G082500.1.p 132 --WNEKNQLLLGIRRA 145
                          ..8899999****997 PP
2Auxin_resp120.11.7e-39170253183
           Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                          aahaa+t+s F+v+YnPras+seFv++++k++ka+  ++vsvGmRf+m fete+ss rr++Gt++g+sdldpvrWpnS+Wrs+k
  Manes.02G082500.1.p 170 AAHAAATNSCFTVFYNPRASPSEFVIPLSKYVKAVFhTRVSVGMRFRMLFETEESSVRRYMGTITGISDLDPVRWPNSHWRSVK 253
                          79********************************87599******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.83E-4928173IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.106.0E-4237159IPR015300DNA-binding pseudobarrel domain
CDDcd100171.98E-2143144No hitNo description
SMARTSM010191.1E-2344146IPR003340B3 DNA binding domain
PROSITE profilePS5086312.33744146IPR003340B3 DNA binding domain
PfamPF023621.1E-2144145IPR003340B3 DNA binding domain
PfamPF065071.5E-34170253IPR010525Auxin response factor
SuperFamilySSF542772.21E-7627707No hitNo description
PfamPF023091.3E-7630717IPR033389AUX/IAA domain
PROSITE profilePS5174524.455633717IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 739 aa     Download sequence    Send to blast
MHADVETDEV YAQMTLQPLT PQEQKDTFLP MELGMPSKQP TNYFCKTLTA SDTSTHGGFS  60
VPRRAAEKVF PPLDFSQQPP AQELIARDLH DVEWKFRHIF RGQPKRHLLT TGWSVFVSAK  120
RLVAGDSVLF IWNEKNQLLL GIRRATRPQT VMPSSVLSSD SMHIGLLAAA AHAAATNSCF  180
TVFYNPRASP SEFVIPLSKY VKAVFHTRVS VGMRFRMLFE TEESSVRRYM GTITGISDLD  240
PVRWPNSHWR SVKVGWDEST AGERQPRVSL WEIEPLTTFP MYPSLFPLRL RRPWHPGPSS  300
LLDNRDEAGN GLMWLRGGTG EQGLHSLNFQ AVNMFPWTQQ RLDPALLGND QNQWYQAMLA  360
SGLGDPLRQQ FMQFQQPFQY LQQSSNHYPL LQLQQQQQAI QQSTSHNILQ AQNQISTESL  420
PRHLLQQQLN NQPDDQAQQQ QHNYHDALQI QGEQLKRQQS NLPSPSFSKT DFMDSSTKFS  480
ASTTPMQNML GSLCAEGSGN LLDFTRTGQS PLTTLTEQLP QQSWVPKYAH SQVNAFTNAV  540
SLPRPYPEKD HAVEPENCSL DAQNATNFGV NIDSSGLLLP TTLPRYATST VDSDVSSMPL  600
GDPGFQSSMY GGVQDSSELL PSAGQVDPPT PSRTFVKVYK SGSVGRSLDI SRFSSYHELR  660
EELAQMFGIE GKLENPHRSG WQLVFVDREN DVLLLGDDPW EAFVNNVWYI KILSPGDVQK  720
MGEQGLESFS PNVGQRIE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1241274115388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.02G082500.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021603558.10.0auxin response factor 8-like isoform X1
RefseqXP_021603560.10.0auxin response factor 8-like isoform X3
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A2C9WEB50.0A0A2C9WEB5_MANES; Auxin response factor
STRINGcassava4.1_001769m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF49582850
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]