PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.04G041700.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family ARF
Protein Properties Length: 321aa    MW: 36117 Da    PI: 7.0347
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.04G041700.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B371.51.1e-22127227198
                          EEEE-..-HHHHTT-EE--HHH.HTT.....---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE- CS
                   B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.....ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkld 85 
                          f k+lt sd+++ g l++ k++aee+     +++++  ++l+ +d++g+ W++++i+r++++r++lt+GW++Fv++++L  gD++vF +d
  Manes.04G041700.1.p 127 FSKKLTASDTSTYGGLSVLKRHAEEClppldMSSEPVMRELIAKDLHGNDWRFQHIFRGQPKRHLLTSGWSGFVSSKRLVPGDTFVFLRD 216
                          88****************************9666666779************************************************65 PP

                          SSSEE..EEEEE- CS
                   B3  86 grsefelvvkvfr 98 
                          +  ++   v+v+r
  Manes.04G041700.1.p 217 D--NGGIGVGVRR 227
                          4..4445677776 PP
2Auxin_resp27.21.7e-102612885683
           Auxin_resp  56 errlsGtvvgvsdldpvrWpnSkWrsLk 83 
                          + r++Gt++ ++d+dp+rW++SkWr+L+
  Manes.04G041700.1.p 261 RPRFTGTIMRIEDIDPLRWRESKWRCLE 288
                          5689**********************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.104.2E-33124230IPR015300DNA-binding pseudobarrel domain
CDDcd100174.09E-19125217No hitNo description
SuperFamilySSF1019361.31E-28125238IPR015300DNA-binding pseudobarrel domain
SMARTSM010191.6E-19127229IPR003340B3 DNA binding domain
PfamPF023627.4E-20127227IPR003340B3 DNA binding domain
PROSITE profilePS5086311.561127229IPR003340B3 DNA binding domain
PfamPF065071.3E-6261287IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 321 aa     Download sequence    Send to blast
MEVHHNGHAA SSTAVRDTET ALYTALWHAC AGPFVTVPRA GELVFYFPQG HIEQVEASEN  60
QAVGQQRPIY NIPWKILCRV INVQLKVDPG TDEVFAQVTL FPQSNQDENT VEYEPPPPPP  120
RFHVRSFSKK LTASDTSTYG GLSVLKRHAE ECLPPLDMSS EPVMRELIAK DLHGNDWRFQ  180
HIFRGQPKRH LLTSGWSGFV SSKRLVPGDT FVFLRDDNGG IGVGVRRGMI EQSNDPIHLN  240
GVATAWEAIS SGSTLFTVHH RPRFTGTIMR IEDIDPLRWR ESKWRCLEVR WDENCGMPLP  300
HRVSPWSIKP IATPMQVDTV *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldy_A1e-1082131618360Auxin response factor 1
4ldy_B1e-1082131618360Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor (PubMed:26959229, PubMed:26716451, PubMed:27645097, PubMed:28167023). Involved in the control of fruit ripening process (PubMed:26959229, PubMed:26716451, PubMed:28167023). Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26959229, PubMed:26716451). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). Regulates vegetative growth, lateral root formation and flower organ senescence, possibly partially by regulating gene expression of auxin and ethylene response factor (ERF) genes (PubMed:28167023). Plays a negative role in axillary shoot meristem formation (PubMed:27645097). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.04G041700.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression in tomato fruits is up-regulated by exogenous application of ethylene and down-regulated by inhibition of ethylene receptors with 1-methylcyclopropene (1-MCP) (PubMed:26959229, PubMed:26716451). Up-regulated by plant hormone abscisic acid (ABA) in tomato fruits (PubMed:26959229). Expression is not up-regulated by plant hormone auxin in tomato fruits (PubMed:26716451). Up-regulated by auxin and gibberellic acid (GA), and down-regulated by ethylene in seedlings (PubMed:28167023). Down-regulated during decapitation-induced axillary shoot development and by excision of immature leaves. Down-regulation is inhibited by the application of auxin on the cut surface (PubMed:27645097). {ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004297494.11e-142PREDICTED: auxin response factor 2
RefseqXP_012090598.21e-146auxin response factor 2
RefseqXP_021911560.11e-145auxin response factor 2, partial
SwissprotQ2LAJ31e-142ARF2A_SOLLC; Auxin response factor 2A
TrEMBLA0A2C9W0R90.0A0A2C9W0R9_MANES; Auxin response factor
STRINGevm.TU.contig_31756.11e-144(Carica papaya)
STRINGXP_004297494.11e-142(Fragaria vesca)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.31e-125auxin response factor 2
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]
  3. Xu T, et al.
    SlARF2a plays a negative role in mediating axillary shoot formation.
    Sci Rep, 2016. 6: p. 33728
    [PMID:27645097]
  4. Ren Z,Liu R,Gu W,Dong X
    The Solanum lycopersicum auxin response factor SlARF2 participates in regulating lateral root formation and flower organ senescence.
    Plant Sci., 2017. 256: p. 103-111
    [PMID:28167023]