PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.05G022000.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family bHLH
Protein Properties Length: 612aa    MW: 67097.2 Da    PI: 6.4597
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.05G022000.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.55.1e-13442488455
                          HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                  HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                          +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  Manes.05G022000.1.p 442 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 488
                          799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.1E-5552240IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474593.93E-18437501IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088817.047438487IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.33E-15441492No hitNo description
Gene3DG3DSA:4.10.280.105.8E-18442501IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-10442488IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.3E-16444493IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 612 aa     Download sequence    Send to blast
MKIEIGMGGG AWNDEDRAMV AAVLGTNALN YLISNSVSNE NLLMAIGSDE NLQNKLSDLV  60
DNPNAWNFSW NYAIFWQISC SKSGDCVLGW GDGSCREPKE GEESEGTRIL NLRFQDETQQ  120
RMRKRVLQKL HTLSGESDDD NYALGLDRVT DTEMFFLASM YFSFASGEGG PGKCLASGKH  180
VWIADALKSG NDYCVRSFLA KSAGIQTIVL VPTDAGVVEL GSVRSVYESM DIVQSIRSTF  240
STNSTVIRAK SMVPVAAPAL PVVNTKKDDN SLFSNVGIVE RVEGIPKIFG QELNHGHGQG  300
YREKLAVRKM EERPSWDVYQ NGNRLAFSGN RNGLHGSSWP HGFGLKQGSP VEVYGSQATT  360
NNIQDLVNGA RNQFQPQKQV QMQIDFSGAT SGPSVIGLPV SVESEHSDVE ASCKEERPGT  420
AEDRRPRKRG RKPANGREEP LNHVEAERQR REKLNQRFYA LRAVVPNISK MDKASLLGDA  480
IAYINELQAK LKLMEAEREK FGSTSRESSA LEVNSNGKNH CQTSEVDIQA SHDEVIVRVS  540
CPLDSHPASR VIKAFKEAQV SVIDSKLAAA NDTVFHTFVI KSQGSEQLTK EKLMAAFSHE  600
SNSLQQVSSV G*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-29436498264Transcription factor MYC2
5gnj_B2e-29436498264Transcription factor MYC2
5gnj_E2e-29436498264Transcription factor MYC2
5gnj_F2e-29436498264Transcription factor MYC2
5gnj_G2e-29436498264Transcription factor MYC2
5gnj_I2e-29436498264Transcription factor MYC2
5gnj_M2e-29436498264Transcription factor MYC2
5gnj_N2e-29436498264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1423431RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.05G022000.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021613223.10.0transcription factor bHLH13-like
RefseqXP_021613224.10.0transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A2C9VUS10.0A0A2C9VUS1_MANES; Uncharacterized protein
STRINGcassava4.1_003856m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]