PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.08G010800.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family E2F/DP
Protein Properties Length: 357aa    MW: 39122.5 Da    PI: 6.4428
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.08G010800.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.42.1e-27102185271
              E2F_TDP   2 keksLrlltqkflklleksee.givtlnevakeLvse.................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          ++++Lr++++k   ++ek+e+ g++t+neva+eLv+e                 d+kn+rRR+YD+lNVL+al++i+k +k+ei+wkg
  Manes.08G010800.1.p 102 SGRGLRQFSMK---VCEKVESkGTTTYNEVADELVAEfadpsnsvsspdqqqqyDEKNIRRRVYDALNVLMALDIISK-DKKEIQWKG 185
                          689********...*****999********************************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0094042.3E-1341356IPR015648Transcription factor DP
Gene3DG3DSA:1.10.10.101.7E-4597191IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.7E-35101185IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.8E-25103185IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.21E-20104186IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd144581.63E-44190293IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440747.85E-43192304No hitNo description
SMARTSM011383.9E-75192354IPR014889Transcription factor DP, C-terminal
PfamPF087811.1E-41193304IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 357 aa     Download sequence    Send to blast
MVTGGTHQDD GDKNHPPATT VSRAGTTRSW GNTTVSGQSV STSGSVGSPS SRSEHAMPTP  60
ASDSTFLRLN HLDIHADDAA TQDAAANKKK KRGQRATGAD KSGRGLRQFS MKVCEKVESK  120
GTTTYNEVAD ELVAEFADPS NSVSSPDQQQ QYDEKNIRRR VYDALNVLMA LDIISKDKKE  180
IQWKGLPRTS LSDIEELKAE RLGLRNRIEK KTAYLQELEE QYIGLQNLIH RNEQLYSSGN  240
APSGGVSLPF ILVQTRPHAT VEVEISEDMQ LVHFDFNSTP FELHDDNYVL KAMKFCERPQ  300
SDDTAANLAN DGGEGCSMSN MIQQQILPNP GTSTPIRPPT SPPIPGIIKA RVKHEH*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B7e-3995190193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.08G010800.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021621224.10.0transcription factor-like protein DPB isoform X1
SwissprotQ9FNY21e-161DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A2C9VCD90.0A0A2C9VCD9_MANES; Uncharacterized protein
STRINGcassava4.1_010769m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33213366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.11e-137Transcription factor DP