PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr1g094740.1
Common NameMTR_1g094740
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family C2H2
Protein Properties Length: 1482aa    MW: 165007 Da    PI: 6.0184
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr1g094740.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.90.0003313661391123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
          zf-C2H2    1 ykCp..dCgksFsrksnLkrHirt.H 23  
                       +kC   +C +sF++k +L+ H r+ +
  Medtr1g094740.1 1366 HKCDldNCRMSFTTKAELQLHKRNlC 1391
                       799999****************9876 PP
2zf-C2H211.60.0008514491475123
                       EEET..TTTEEESSHHHHHHHHHH..T CS
          zf-C2H2    1 ykCp..dCgksFsrksnLkrHirt..H 23  
                       y+C+   Cg sF+  s++ rH r+  H
  Medtr1g094740.1 1449 YQCKveGCGLSFRFISDFSRHRRKtgH 1475
                       99*********************9777 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM005454.8E-141555IPR003349JmjN domain
PROSITE profilePS5118314.2711657IPR003349JmjN domain
PfamPF023751.5E-141750IPR003349JmjN domain
SMARTSM005585.3E-47291460IPR003347JmjC domain
PROSITE profilePS5118436.772291460IPR003347JmjC domain
SuperFamilySSF511976.59E-27292456No hitNo description
PfamPF023731.9E-35325443IPR003347JmjC domain
Gene3DG3DSA:3.30.160.602.7E-513581388IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003551413661388IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.63513891418IPR007087Zinc finger, C2H2
SMARTSM003550.5913891413IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028013911413IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.6E-613911418IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.25E-1014071447No hitNo description
SMARTSM003550.001914191443IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.04814191448IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.8E-1214191443IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS00028014211443IPR007087Zinc finger, C2H2
SuperFamilySSF576675.35E-914371471No hitNo description
Gene3DG3DSA:3.30.160.603.0E-1114441472IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.3414491475IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.55414491480IPR007087Zinc finger, C2H2
PROSITE patternPS00028014511475IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009741Biological Processresponse to brassinosteroid
GO:0009826Biological Processunidimensional cell growth
GO:0032259Biological Processmethylation
GO:0033169Biological Processhistone H3-K9 demethylation
GO:0048577Biological Processnegative regulation of short-day photoperiodism, flowering
GO:0048579Biological Processnegative regulation of long-day photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0008168Molecular Functionmethyltransferase activity
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 1482 aa     Download sequence    Send to blast
MGNVEIPNWL EGLPLAPEFR PTDTEFSDPI AYISKIEQKA GKFGICKIIP PLPKPSKKYV  60
FSNLNKSLLK RPELGPDGSS LGAGNSWKMG SGDSGNDGES RALFTTRQQE VGQNVKKSKG  120
VVQKSMACVH KQVWQSGEVY TIEQFESKSK TFSRSVLGTA KDVSPLVVES MFWKAASEKP  180
IYVEYANDVP GSAFGESQGQ FYRSHRRQRK RTDYKSRVDS SVCKETEMGG VNDTHNNESN  240
GIASPSHAES CLETSKSAMT LSTSTPNEVS QPSKEMISDA DNDMQGTAGW KLSNSPWNLQ  300
VIPRASGSLT RFMPDDIPGV TSPMIYIGML FSWFAWHVED HELHSLNFLH TGSSKTWYSI  360
PGNYAFAFEE VIRTEGYGGD VDQLAALKLL GEKTTLLSPE VVVASGIPCC RLVQNPGEFV  420
VTFPRAYHVG FSHGFNCGEA ANFGTPQWLG IAKEAAVRRA TMNHLPMLSH QQLLYLLTMS  480
FISSVPRTLL PGVRSSRLRD RQKEEREILV KQAFIEDMLH ENKLLSILLG KEATKEVVLW  540
NVDLLPDSGK YRQLPDLAST SGTYMADMSN DNISSADKSS HCLLDEMSLY MENLTDSDVG  600
YDDLPCHFQT DSGALVCVGC GILGFPFMTL IQPTEKLIME LPDNHLVEDS SLNSVGSFHS  660
AVSRDLSVSE LACAKYSPDQ SLNECNKCWN TSSTFLKPRI FCLEHAVQVV EMLQSKGGAN  720
VLIICHSDYP KIKAHARAVA EEIQGDFDYN EVPMDIASPE NLALIDLAID GKELDECEDW  780
TSKLGLNLRF CVNNINKSPC KQVPFTLALG MQFYDKRPGL SLNWHSQKAR SKRSNRLAQS  840
KPDDIQRKKD DQLQERIDGS TAEKKLLQYS RRKFKPKQSC FSVAITVCEC ESHEKSKNVS  900
AVLSAEHYKC VSKDELDTDN FRSDCALSRG SASAAMSPLH NEIQNAEAPT SMSLNTSVSE  960
KCSKENQNCQ NNKYSGSLSN GIDKNVDVFG NNQITEAIAI GSKCDSLDLV GEGYQEQQSA  1020
CKSNSEAVLS TASLVNQTAL ATVDGSFESP INNQAEERVS NSMSLKETIE RESKSLNEMD  1080
KEPLNDDKEI SEHAPTADIC EVPRELYASA NFHNTVDLDA MQQERQVGES GEQEIIQSTH  1140
ISAKQLYEST SGEYAEGLHN EVILESSKQC QIQNENITIE EHVSNYVAKG DNRSITISEI  1200
SCSDVSAETC PEKDSCIQFV SNTEKEMEIQ PIHRVDEELS ISIQECSQTE KKTCGRENVN  1260
GSEVDLSQDD GELESCELTT EVPRSNAGKK KRRKMEDTEN NQFDCYDFIR SPCERLRPRT  1320
GKTATGKSVG DNSQNDEENR VAKRTRKPAE ASIPRKDKKS NVKRPHKCDL DNCRMSFTTK  1380
AELQLHKRNL CPHEGCGKKF SSHKYALIHQ RVHEDDRPFK CTWKGCSMSF KWSWARTEHL  1440
RVHTGEKPYQ CKVEGCGLSF RFISDFSRHR RKTGHCVKSP A*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ip0_A8e-56275474142346Transcription factor jumonji (Jmj) family protein
6ip4_A8e-56275474142346Arabidopsis JMJ13
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
112881292KKKRR
212881293KKKRRK
312891293KKRRK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.237160.0root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed at low levels in cotyledons and leaves. Detected in inflorescences, stems, roots and siliques but not in shoot apical meristems or root tips. {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18713399}.
Functional Description ? help Back to Top
Source Description
UniProtActs probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:19946624}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr1g094740.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1449280.0AC144928.17 Medicago truncatula clone mth2-8a18, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003591873.20.0probable lysine-specific demethylase ELF6
SwissprotQ6BDA00.0ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBLG7I5110.0G7I511_MEDTR; Lysine-specific demethylase ELF6-like protein, putative
STRINGXP_004496256.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF80313034
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G04240.10.0C2H2 family protein
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C
    Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A.
    PLoS ONE, 2013. 8(7): p. e67987
    [PMID:23976921]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Crevillén P, et al.
    Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state.
    Nature, 2014. 515(7528): p. 587-90
    [PMID:25219852]
  5. Yang H,Howard M,Dean C
    Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74
    [PMID:27482092]