PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr2g014340.1
Common NameMTR_2g014340
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family ERF
Protein Properties Length: 201aa    MW: 22077.6 Da    PI: 8.2341
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr2g014340.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2643.1e-201867255
              AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                     +++GVr ++ +gr++AeIrdp   gk+ r++lg+f+taeeAa+a++ a+++++g
  Medtr2g014340.1 18 HFRGVRKRP-WGRYAAEIRDP---GKKSRVWLGTFDTAEEAARAYDSAARQFRG 67
                     69*******.**********8...557************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000181.57E-311775No hitNo description
PROSITE profilePS5103223.7491875IPR001471AP2/ERF domain
SMARTSM003802.9E-381881IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.5E-321875IPR001471AP2/ERF domain
SuperFamilySSF541711.37E-221876IPR016177DNA-binding domain
PfamPF008475.6E-141867IPR001471AP2/ERF domain
PRINTSPR003673.7E-111930IPR001471AP2/ERF domain
PRINTSPR003673.7E-114157IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 201 aa     Download sequence    Send to blast
MAPKVVKNGG VNGVKEAHFR GVRKRPWGRY AAEIRDPGKK SRVWLGTFDT AEEAARAYDS  60
AARQFRGPKA KTNFPFPIEN IKIHSPSQSS TVESSSRDRD AAADSSPLDL NLAPAFQHRF  120
TPMPAVNQTF CFDPVLRAGM VNSRSCYGYG FEYNPSMEAS GFHATVGAQS DSDSSSVIDL  180
NHHGRSFDFD LNYPPLEDML *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A1e-211578266ATERF1
3gcc_A1e-211578266ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.149250.0leaf| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, in cultured cells and at low levels in buds and leaves. Highly expressed in cell culture, especially during the exponential phase. {ECO:0000269|PubMed:11440157, ECO:0000269|PubMed:7756828}.
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional repressor. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase/phosphatase cascade, and to be influenced by methyl-jasmonate. May regulate other AtERFs (By similarity). {ECO:0000250, ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:10792818, ECO:0000269|PubMed:12654868, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr2g014340.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Strongly induced by ethephon (ethylene-releasing compound) in buds and to lower extent in leaves. Strongly induced by cycloheximide and mechanical stimuli. Wounding leads to a both local and systemical transient expression, independently of ethylene, and through a de-novo-protein-synthesis-independent regulation. Not influenced by methyl-jasmonate. Induction by purified xylanase from Trichoderma viride (TvX) and another elicitor from Phytophthora infestans (PiE), that appears to be mediated by a protein kinase cascade, and to be negatively regulated by protein phosphatases. {ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:12090623, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1551570.0AC155157.1 Medicago truncatula chromosome 2 BAC clone mth2-53f22, complete sequence.
GenBankBT1379670.0BT137967.1 Medicago truncatula clone JCVI-FLMt-2J8 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003593630.11e-149ethylene-responsive transcription factor 4
SwissprotQ404772e-46ERF4_TOBAC; Ethylene-responsive transcription factor 4
TrEMBLA0A396J6951e-147A0A396J695_MEDTR; Putative transcription factor AP2-EREBP family
TrEMBLG7ISE81e-147G7ISE8_MEDTR; Ethylene response factor
STRINGAES638811e-148(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33034189
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G44210.11e-27erf domain protein 9
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Ogata T, et al.
    Involvement of NtERF3 in the cell death signalling pathway mediated by SIPK/WIPK and WRKY1 in tobacco plants.
    Plant Biol (Stuttg), 2015. 17(5): p. 962-72
    [PMID:25996234]