PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr2g089000.1

Common Name

MTR_2g089000

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

bHLH

Protein Properties

Length: 261aa MW: 29373.1 Da PI: 5.2576

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr2g089000.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.8	2.5e-10	111	156	6	54
HHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 6 nerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 rE+ RRd++N++f eL ++l ++ + +K +K++ L Av+ + +L Medtr2g089000.1 111 AGREKVRRDKLNDRFMELSSVLEPD---TLPKTDKVSLLNDAVRVVTQL 156 569********************...9*************99988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	8.77E-13	96	172	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	12.163	105	156	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	8.4E-8	110	156	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.8E-7	111	162	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.1E-12	113	178	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.24E-7	113	161	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 261 aa Download sequence Send to blast
MDMDSTGGSS IWLYDYGYDD ISISAADFMA SDSSAAASTF TWMPQPQSQT QIINPPSSHM 60 SLEMDYSLDS TVMESNPSKR MEMEYSLDST VLENGPSKRL RTESYASSSK AGREKVRRDK 120 LNDRFMELSS VLEPDTLPKT DKVSLLNDAV RVVTQLRNEA ERLKERNDEL REKVKELKAE 180 KKELRDEKNK LKLDKEKLEQ QVKLASVQSN FLSNAMAAKG QTANHKLMPF IGYPGISMWQ 240 FMSPATVDTS QDHLLRPPVA *

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.5764	0.0	root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269\|PubMed:17028341}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr2g089000.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT142086	0.0	BT142086.1 Medicago truncatula clone JCVI-FLMt-5A23 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003597042.1	0.0	transcription factor bHLH115
Swissprot	Q9FH37	1e-64	ILR3_ARATH; Transcription factor ILR3
TrEMBL	G7IKM3	0.0	G7IKM3_MEDTR; BHLH domain class transcription factor
STRING	AES67293	0.0	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF14916	12	14

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	4e-43	bHLH family protein

Link Out ? help Back to Top
Phytozome	Medtr2g089000.1
Entrez Gene	11408870

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]