PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr2g093740.2
Common NameMTR_2g093740
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family ARF
Protein Properties Length: 824aa    MW: 91729.6 Da    PI: 7.2349
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr2g093740.2genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B368.96.7e-22168282199
                      EEEE-..-HHHHTT-EE--HHH.HTT...................---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT-- CS
               B3   1 ffkvltpsdvlksgrlvlpkkfaeeh...................ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLk 75 
                      f+k+lt sd++++g +++p++ ae++                   + +++ s++l+ +d++g  W++++iyr++++r++lt+GW+ Fv++++L 
  Medtr2g093740.2 168 FCKTLTASDTSTHGGFSVPRRAAEDCfpplvqhyepvwiclfedyK-QQRPSQELVAKDLHGVGWKFRHIYRGQPRRHLLTTGWSIFVSQKNLV 260
                      99******************************99999999999863.3345679**************************************** PP

                      TT-EEEEEE-SSSEE..EEEEE-S CS
               B3  76 egDfvvFkldgrsefelvvkvfrk 99 
                      +gD v+F   + +++el+++++r+
  Medtr2g093740.2 261 SGDAVLFL--RGENGELRLGIRRA 282
                      ********..4499999****996 PP
2Auxin_resp119.33e-39307389182
       Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrl.sGtvvgvsdldpvrWpnSkWrsL 82 
                      +a+a+s ks+F+v+Y+Pras+++Fvv+++k+ k+++++v++G+Rfkm+fe+++s+err+ sG+v+g+sdldp++Wp+SkWr+L
  Medtr2g093740.2 307 VANAISAKSMFHVFYSPRASHADFVVPYQKYAKSIRNPVTIGTRFKMKFEMDESPERRCsSGIVTGMSDLDPYKWPKSKWRCL 389
                      689********************************************************9**********************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.35E-39164291IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.102.0E-36165293IPR015300DNA-binding pseudobarrel domain
CDDcd100171.13E-19166281No hitNo description
PROSITE profilePS5086311.843168283IPR003340B3 DNA binding domain
SMARTSM010198.8E-21168283IPR003340B3 DNA binding domain
PfamPF023624.3E-20168282IPR003340B3 DNA binding domain
PfamPF065073.4E-33307389IPR010525Auxin response factor
PROSITE profilePS5174522.209695779IPR000270PB1 domain
SuperFamilySSF542771.49E-10698774No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009734Biological Processauxin-activated signaling pathway
GO:0010050Biological Processvegetative phase change
GO:0010158Biological Processabaxial cell fate specification
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 824 aa     Download sequence    Send to blast
MEIDLNDSIT EVKKNVCSNG KCEKSVCCVC TLSSSSSPTC SSSSSTSAIV SSSYLELWHA  60
CAGPLTSLPK KGNVVVYFPQ GHLEQVASLS LFSSLEIPTY GLQPQILCRV VNVQLLANKE  120
NDEVYTQVAL LPQAELAGMC LDDKEPEGLE ADDEGNGRSP TKLASHMFCK TLTASDTSTH  180
GGFSVPRRAA EDCFPPLVQH YEPVWICLFE DYKQQRPSQE LVAKDLHGVG WKFRHIYRGQ  240
PRRHLLTTGW SIFVSQKNLV SGDAVLFLRG ENGELRLGIR RAARPRNGLP ESIIGNQSCS  300
PSFLSSVANA ISAKSMFHVF YSPRASHADF VVPYQKYAKS IRNPVTIGTR FKMKFEMDES  360
PERRCSSGIV TGMSDLDPYK WPKSKWRCLM VRWDEDIGAN HQDRVSPWEI DPSTSLPPLN  420
IQSSRRLKKL RTGLHVESPS HFITAGDSGF MDFDESIRSS KVLQGQEKTS FMSLYYGCDT  480
VTKQKEFDIN SLRHTNLASN GARKITSSEF TRIQPSSYAD FTEMNRFPRV LQAQEIYPLR  540
SLTGKVDLNL NSWGKTNVSY TKYNLHNATK LNFHSLGSEV LQNSSFPYGD IHKVGQGSSM  600
LCSKPTNFQL GNVSFNTPSS QIGALRNEVG LSSFKIRNEQ KLQNDISAAT SLDANIRISN  660
DENFKEMVNP CKLFGFSLSA AAETTSQNLQ NSAKRSCTKV HKQGSLVGRA IDLSRLSSYN  720
DLVSELERLF GMEGLLRDPD KGWRILYTDS ENDIMVVGDD PWHEFCDMVS KIHIYTQEEV  780
EKMTIGMMND DNQSCLEQTP LIMEASKSSS VGQPDSSTTV VRI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldy_A1e-1165641522357Auxin response factor 1
4ldy_B1e-1165641522357Auxin response factor 1
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269|PubMed:10476078}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr2g093740.2
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1508910.0AC150891.3 Medicago truncatula chromosome 2 clone mth2-76a9, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013465277.10.0auxin response factor 4 isoform X1
SwissprotQ9ZTX90.0ARFD_ARATH; Auxin response factor 4
TrEMBLA0A072VC050.0A0A072VC05_MEDTR; Auxin response factor
STRINGAES674420.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF52363252
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60450.10.0auxin response factor 4
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY
    TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors.
    Mol. Gen. Mikrobiol. Virusol., 2013.
    [PMID:24003511]
  3. Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y
    The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis.
    Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71
    [PMID:26108442]
  4. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  5. Matsumura Y, et al.
    A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis.
    Biol Open, 2016. 5(7): p. 942-54
    [PMID:27334696]
  6. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  7. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]