PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr3g080100.1
Common NameMTR_3g080100
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family HD-ZIP
Protein Properties Length: 256aa    MW: 29767.3 Da    PI: 4.7863
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr3g080100.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox55.59.6e-1862112656
                      S--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
         Homeobox   6 tftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                      ++  +q+++Le+ Fe ++++  e++ +LA+ lgL+ rqV++WFqNrRa+ k
  Medtr3g080100.1  62 RLGYDQVKALEKSFELDNKLEPERKVKLAEDLGLQPRQVSIWFQNRRARTK 112
                      56679********************************************98 PP
2HD-ZIP_I/II124.16.8e-4058150193
      HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 
                      ekkrrl  +qvk+LE+sFe ++kLeperKv+la++Lglqprqv +WFqnrRARtktkqlE+dy++Lk+++d lk e ++L++e+e+L+++l+e
  Medtr3g080100.1  58 EKKRRLGYDQVKALEKSFELDNKLEPERKVKLAEDLGLQPRQVSIWFQNRRARTKTKQLERDYSVLKSNFDVLKVEYTNLQQENETLTRKLRE 150
                      69**************************************************************************************99986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007116.7354114IPR001356Homeobox domain
SMARTSM003895.7E-1657118IPR001356Homeobox domain
CDDcd000861.62E-1359115No hitNo description
SuperFamilySSF466891.28E-1759125IPR009057Homeodomain-like
PfamPF000465.1E-1561112IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.603.3E-1864121IPR009057Homeodomain-like
PRINTSPR000319.0E-68594IPR000047Helix-turn-helix motif
PROSITE patternPS00027089112IPR017970Homeobox, conserved site
PRINTSPR000319.0E-694110IPR000047Helix-turn-helix motif
PfamPF021831.6E-14114155IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 256 aa     Download sequence    Send to blast
MKRFNNSETM ASLLSMYQSK EVDVDQRNEA KGYSEEFQAM LDRLEQEDSY EDGSPMLEKK  60
RRLGYDQVKA LEKSFELDNK LEPERKVKLA EDLGLQPRQV SIWFQNRRAR TKTKQLERDY  120
SVLKSNFDVL KVEYTNLQQE NETLTRKLRE LKAKLLRVES NELEKEVECP ISRGIERGGS  180
ESNSSGIIKE ESNVDSPMCF NGSLPSSMIN LVHYYDSRGS QENVFQNQFM RMEEQNFLSN  240
SELFSFFSVD QSPTL*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1106114RRARTKTKQ
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Localized primarily to the hypocotyl of germinating seedlings. {ECO:0000269|PubMed:12678559}.
UniprotTISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16055682}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that acts as a positive regulator of ABA-responsiveness, mediating the inhibitory effect of ABA on growth during seedling establishment. Binds to the DNA sequence 5'-CAATNATTG-3'. {ECO:0000269|PubMed:12678559}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr3g080100.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by abscisic acid (ABA) and by salt stress. {ECO:0000269|PubMed:12678559, ECO:0000269|PubMed:16055682}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCU0248640.0CU024864.5 M.truncatula DNA sequence from clone MTH2-9F11 on chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003601381.10.0homeobox-leucine zipper protein ATHB-5
SwissprotP466677e-47ATHB5_ARATH; Homeobox-leucine zipper protein ATHB-5
TrEMBLG7J6Q00.0G7J6Q0_MEDTR; Homeobox associated leucine zipper protein
STRINGAES716320.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF18683489
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G65310.12e-44homeobox protein 5
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Cassan-Wang H, et al.
    Identification of novel transcription factors regulating secondary cell wall formation in Arabidopsis.
    Front Plant Sci, 2013. 4: p. 189
    [PMID:23781226]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Song L, et al.
    A transcription factor hierarchy defines an environmental stress response network.
    Science, 2017.
    [PMID:27811239]
  5. Stamm P, et al.
    The Transcription Factor ATHB5 Affects GA-Mediated Plasticity in Hypocotyl Cell Growth during Seed Germination.
    Plant Physiol., 2017. 173(1): p. 907-917
    [PMID:27872245]