PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr3g080100.2

Common Name

MTR_3g080100

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

HD-ZIP

Protein Properties

Length: 217aa MW: 25222.3 Da PI: 4.8711

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr3g080100.2	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	55.9	7.3e-18	23	73	6	56
S--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 6 tftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 ++ +q+++Le+ Fe ++++ e++ +LA+ lgL+ rqV++WFqNrRa+ k Medtr3g080100.2 23 RLGYDQVKALEKSFELDNKLEPERKVKLAEDLGLQPRQVSIWFQNRRARTK 73 56679********************************************98 PP
2	HD-ZIP_I/II	124.6	4.7e-40	19	111	1	93
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 ekkrrl +qvk+LE+sFe ++kLeperKv+la++Lglqprqv +WFqnrRARtktkqlE+dy++Lk+++d lk e ++L++e+e+L+++l+e Medtr3g080100.2 19 EKKRRLGYDQVKALEKSFELDNKLEPERKVKLAEDLGLQPRQVSIWFQNRRARTKTKQLERDYSVLKSNFDVLKVEYTNLQQENETLTRKLRE 111 69**************************************************************************************99986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	16.73	15	75	IPR001356	Homeobox domain
SMART	SM00389	5.7E-16	18	79	IPR001356	Homeobox domain
SuperFamily	SSF46689	9.41E-18	20	86	IPR009057	Homeodomain-like
CDD	cd00086	1.00E-13	20	76	No hit	No description
Pfam	PF00046	3.8E-15	22	73	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	2.4E-18	24	82	IPR009057	Homeodomain-like
PRINTS	PR00031	7.0E-6	46	55	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	50	73	IPR017970	Homeobox, conserved site
PRINTS	PR00031	7.0E-6	55	71	IPR000047	Helix-turn-helix motif
Pfam	PF02183	1.2E-14	75	116	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 217 aa Download sequence Send to blast
MLDRLEQEDS YEDGSPMLEK KRRLGYDQVK ALEKSFELDN KLEPERKVKL AEDLGLQPRQ 60 VSIWFQNRRA RTKTKQLERD YSVLKSNFDV LKVEYTNLQQ ENETLTRKLR ELKAKLLRVE 120 SNELEKEVEC PISRGIERGG SESNSSGIIK EESNVDSPMC FNGSLPSSMI NLVHYYDSRG 180 SQENVFQNQF MRMEEQNFLS NSELFSFFSV DQSPTL*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	67	75	RRARTKTKQ

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Localized primarily to the hypocotyl of germinating seedlings. {ECO:0000269\|PubMed:12678559}.
Uniprot	TISSUE SPECIFICITY: Widely expressed. {ECO:0000269\|PubMed:16055682}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that acts as a positive regulator of ABA-responsiveness, mediating the inhibitory effect of ABA on growth during seedling establishment. Binds to the DNA sequence 5'-CAATNATTG-3'. {ECO:0000269\|PubMed:12678559}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr3g080100.2

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by abscisic acid (ABA) and by salt stress. {ECO:0000269\|PubMed:12678559, ECO:0000269\|PubMed:16055682}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	CU024864	0.0	CU024864.5 M.truncatula DNA sequence from clone MTH2-9F11 on chromosome 3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003601381.1	1e-157	homeobox-leucine zipper protein ATHB-5
Swissprot	P46667	4e-46	ATHB5_ARATH; Homeobox-leucine zipper protein ATHB-5
TrEMBL	G7J6Q0	1e-155	G7J6Q0_MEDTR; Homeobox associated leucine zipper protein
STRING	AES71632	1e-156	(Medicago truncatula)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G65310.1	1e-43	homeobox protein 5

Link Out ? help Back to Top
Phytozome	Medtr3g080100.2
Entrez Gene	11429040

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Cassan-Wang H, et al. Identification of novel transcription factors regulating secondary cell wall formation in Arabidopsis. Front Plant Sci, 2013. 4: p. 189 [PMID:23781226] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Song L, et al. A transcription factor hierarchy defines an environmental stress response network. Science, 2017. [PMID:27811239] Stamm P, et al. The Transcription Factor ATHB5 Affects GA-Mediated Plasticity in Hypocotyl Cell Growth during Seed Germination. Plant Physiol., 2017. 173(1): p. 907-917 [PMID:27872245]