PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr4g066460.1

Common Name

MTR_4g066460, TSAR2

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

bHLH

Protein Properties

Length: 330aa MW: 37038 Da PI: 5.523

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr4g066460.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	34.7	3.3e-11	155	200	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 h ++Er+RR+++ ++f L l+P++ kK++K ++L +++Y+k+L Medtr4g066460.1 155 DHIMAERNRREKLTQSFIALAALVPNL-----KKMDKLSVLIDTIKYMKEL 200 599**********************.....9**************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.519	151	200	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	8.2E-15	155	217	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	9.68E-15	156	216	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.86E-11	156	205	No hit	No description
Pfam	PF00010	5.8E-9	156	200	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.3E-12	157	206	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 330 aa Download sequence Send to blast
MEEINNSAMK VSSSISSWLS DLEMDEYNIF AEECNLNFLD ADVGGFLSND ISNVFQEQNK 60 QQCLSLGSTF HETIDNSDKN NESLSPSFQF QVPSFDNPPN SSPTNSKENI ETIPLSPTDL 120 ENMNHSTETS KGSLENKKLE TKTSKSKRPR AHGRDHIMAE RNRREKLTQS FIALAALVPN 180 LKKMDKLSVL IDTIKYMKEL KNRLEDVEEQ NKKTKKKSST KPCLCSDEDS SSCEDNIECV 240 VGSPFQVEAR VLGKQVLIRI QCKEHKGLLV KIMVEIQKFQ LFVVNNSVLP FGDSTLDITI 300 IAQLGEGYNL SIKELVKNVR MALLKFTSS*

Function -- GeneRIF ? help Back to Top
The bHLH transcription factors TSAR1 and TSAR2 regulate triterpene saponin biosynthesis. [PMID: 26589673]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr4g066460.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KR349466	0.0	KR349466.1 Medicago truncatula triterpene saponin activating regulator 2 (TSAR2) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013456259.1	0.0	transcription factor bHLH18
TrEMBL	A0A072UWR1	0.0	A0A072UWR1_MEDTR; Basic helix loop helix (BHLH) DNA-binding family protein
STRING	AES90810	1e-103	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF11069	12	38

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37850.1	6e-36	bHLH family protein

Link Out ? help Back to Top
Phytozome	Medtr4g066460.1
Entrez Gene	25492635

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Mertens J, et al. The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula. Plant Physiol., 2016. 170(1): p. 194-210 [PMID:26589673]