PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr4g073100.2

Common Name

MTR_4g073100

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

bZIP

Protein Properties

Length: 268aa MW: 29030.5 Da PI: 6.5906

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr4g073100.2	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	24.4	6.4e-08	91	135	7	51
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 7 errkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkelee 51 +r N+eA r++R++Kka+ + Le++v +L a N+ L +l+ Medtr4g073100.2 91 KKRPVGNKEAVRKYREKKKARAASLEDEVMKLRALNQHLMRKLQG 135 466778*********************************999874 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	4.3E-7	83	152	IPR004827	Basic-leucine zipper domain
Gene3D	G3DSA:1.20.5.170	1.6E-12	84	153	No hit	No description
Pfam	PF07716	5.4E-12	88	142	IPR004827	Basic-leucine zipper domain
CDD	cd14686	1.32E-10	91	144	No hit	No description
SuperFamily	SSF57959	1.5E-6	92	135	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0071294	Biological Process	cellular response to zinc ion
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 268 aa Download sequence Send to blast
MEDGELDFSN QDVFSSPNMG EFQTSGSMDS FFDELLKDTH ACTHTHTCNP PGPDFSHTHT 60 CYHVHTKIVP AEDDQVGTDD TAESAEKKSS KKRPVGNKEA VRKYREKKKA RAASLEDEVM 120 KLRALNQHLM RKLQGQAALE AEVARLKCLL VDIRGRIEGE IGSFPYQKPA NVNPAMNMPG 180 SHVMNPCNVQ CDDRAYCLRP DGKIAAEVAS PNEEGFDGCE FESLQCMGGQ NLGLKDLRGC 240 GGGPALSNVN SQASSKRKGG SRAAKAG*

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.6963	0.0	leaf\| root

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the response to zinc ion deficiency. Binds to the consensus sequence 5'-[AG]TGTCGACA[CT]-3' also called zinc deficiency response element (ZDRE). The ZDRE sequence is conserved in the plant kingdom and present in the promoters of genes that constitute the primary response to zinc deficiency, comprising additional ZIP metal transporter genes (PubMed:20479230, PubMed:26306426). Required for zinc accumulation in roots. Mediates the expression of the zinc transporters ZIP3, ZIP4, ZIP5 and ZIP9 during growth in zinc-deficient conditions. ZIP9 transporter is involved in zinc uptake in roots (PubMed:26306426). {ECO:0000269\|PubMed:20479230, ECO:0000269\|PubMed:26306426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr4g073100.2

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by zinc deficiency. {ECO:0000269\|PubMed:20479230}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT051934	0.0	BT051934.1 Medicago truncatula clone MTYF5_F6_F7_F81G-B-24 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003607180.1	0.0	basic leucine zipper 23
Swissprot	Q8VY76	1e-111	BZP19_ARATH; Basic leucine zipper 19
TrEMBL	B7FIL7	0.0	B7FIL7_MEDTR; BZIP transcription factor
STRING	AES89377	0.0	(Medicago truncatula)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G16770.1	1e-95	bZIP family protein

Link Out ? help Back to Top
Phytozome	Medtr4g073100.2
Entrez Gene	11438735

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Azevedo H, et al. Transcriptomic profiling of Arabidopsis gene expression in response to varying micronutrient zinc supply. Genom Data, 2016. 7: p. 256-8 [PMID:26981422] Castro PH, et al. Phylogenetic analysis of F-bZIP transcription factors indicates conservation of the zinc deficiency response across land plants. Sci Rep, 2017. 7(1): p. 3806 [PMID:28630437] Henriques AR,Farias DDR,Costa de Oliveira A Identification and characterization of the bZIP transcription factor involved in zinc homeostasis in cereals. Genet. Mol. Res., 2017. [PMID:28671251] Nazri AZ,Griffin JHC,Peaston KA,Alexander-Webber DGA,Williams LE F-group bZIPs in barley-a role in Zn deficiency. Plant Cell Environ., 2017. 40(11): p. 2754-2770 [PMID:28763829] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]