PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g077803.1
Common NameMTR_4g077803
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family E2F/DP
Protein Properties Length: 345aa    MW: 37887.1 Da    PI: 5.4937
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g077803.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP87.21.2e-2793175271
          E2F_TDP   2 keksLrlltqkflklleksee.givtlnevakeLvse................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                      ++++Lr++++k   ++ek+e+ g++t+neva+eLv+e                d+kn+rRR+YD+lNVL+a+++i+k +k+ei+wkg
  Medtr4g077803.1  93 SGRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfadpinsvltpdkqqyDEKNIRRRVYDALNVLMAMDIISK-DKKEIQWKG 175
                      689********...*****999*******************************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0094041.5E-1292344IPR015648Transcription factor DP
Gene3DG3DSA:1.10.10.107.1E-4688180IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.1E-3492175IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.1E-2594175IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.04E-2195176IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd144581.72E-43180283IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440741.46E-41181292No hitNo description
SMARTSM011387.2E-70182342IPR014889Transcription factor DP, C-terminal
PfamPF087819.2E-41183297IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 345 aa     Download sequence    Send to blast
MGTRSQQSCV DEDEEEFIGC GTTISGQSGS TSRSAGGLAS SRSEQTIGTA AGDNTALRLN  60
HLDIQDDDAA SQGVVASKKK KRGQQRATGG DKSGRGLRQF SMKVCEKVES KGRTTYNEVA  120
DELVAEFADP INSVLTPDKQ QYDEKNIRRR VYDALNVLMA MDIISKDKKE IQWKGLPRTS  180
LNDIEELKTE RLGLRNRIER KSSYLQELEE QFVGLQNLVK RNEQLYSSGN PPSGGVSLPF  240
ILVQTRPHAT VEVEISEDMQ LVHFDFNSTP FELHDDNYVL KAMEFGDRTQ SDIVTHNVTD  300
GGEGSSMSGM HQSQVPPSAS SVSTRPPTSP PLPGILKARV KQEH*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B5e-3986180193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during the whole cell cycle. {ECO:0000269|PubMed:11669580}.
UniprotTISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g077803.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013456630.10.0transcription factor-like protein DPB isoform X1
SwissprotQ9FNY21e-150DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A072UMP70.0A0A072UMP7_MEDTR; Putative transcription factor E2F-DP family
STRINGXP_004505604.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33213366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.11e-144Transcription factor DP
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]